A Novel Multiplexed, Image-Based Approach to Detect Phenotypes That Underlie Chromosome Instability in Human Cells

por Thompson, Laura L., McManus, Kirk J.
Publicado 2015

An Automated, Single Cell Quantitative Imaging Microscopy Approach to Assess Micronucleus Formation, Genotoxicity and Chromosome Instability

por Lepage, Chloe C., Thompson, Laura L., Larson, Bradley, McManus, Kirk J.
Publicado 2020

Reduced SKP1 Expression Induces Chromosome Instability through Aberrant Cyclin E1 Protein Turnover

por Thompson, Laura L., Baergen, Allison K., Lichtensztejn, Zelda, McManus, Kirk J.
Publicado 2020

The SCF Complex Is Essential to Maintain Genome and Chromosome Stability

por Thompson, Laura L., Rutherford, Kailee A., Lepage, Chloe C., McManus, Kirk J.
Publicado 2021

Aberrant SKP1 Expression: Diverse Mechanisms Impacting Genome and Chromosome Stability

por Thompson, Laura L., Rutherford, Kailee A., Lepage, Chloe C., McManus, Kirk J.
Publicado 2022

Evolving Therapeutic Strategies to Exploit Chromosome Instability in Cancer

por Thompson, Laura L., Jeusset, Lucile M-P., Lepage, Chloe C., McManus, Kirk J.
Publicado 2017

Reduced SKP2 Expression Adversely Impacts Genome Stability and Promotes Cellular Transformation in Colonic Epithelial Cells

por Neudorf, Nicole M., Thompson, Laura L., Lichtensztejn, Zelda, Razi, Tooba, McManus, Kirk J.
Publicado 2022

Mate-pair sequencing identifies a cryptic BMPR2 mutation in hereditary pulmonary arterial hypertension

por Chalmers, Sarah J., Murphy, Stephen J., Thompson, Laura L., Hoppman, Nicole L., Smadbeck, James B., Balcom, Jessica R., Harris, Faye R., Frantz, Robert P., Vasmatzis, George, E. Wylam, Mark
Publicado 2021