Broadening our understanding of the genetics of Juvenile Idiopathic Arthritis (JIA): Interrogation of three dimensional chromatin structures and genetic regulatory elements within...

por Jiang, Kaiyu, Kessler, Haeja, Park, Yungki, Sudman, Marc, Thompson, Susan D., Jarvis, James N.
Publicado 2020

Association of SLCO1B1 *14 Allele with Poor Response to Methotrexate in Juvenile Idiopathic Arthritis Patients

por Ramsey, Laura B., Moncrieffe, Halima, Smith, Chelsey N., Sudman, Marc, Marion, Miranda C., Langefeld, Carl D., Becker, Mara L., Thompson, Susan D.
Publicado 2019

4277 Functional consequences of the juvenile idiopathic arthritis risk variant at 1q24.3

por Moncrieffe, Halima, Dunn, Katelyn, Huang, Yongbo, Chen, Xiaoting, Langefeld, Carl D., Weirauch, Matthew T., Harley, John B., Kottyan, Leah C., Thompson, Susan D.
Publicado 2020

Association of the IL2RA/CD25 Gene With Juvenile Idiopathic Arthritis

por Hinks, Anne, Ke, Xiayi, Barton, Anne, Eyre, Steve, Bowes, John, Worthington, Jane, Thompson, Susan D, Langefeld, Carl D, Glass, David N, Thomson, Wendy
Publicado 2009

Association of the 5-aminoimidazole-4-carboxamide ribonucleotide transformylase gene with response to methotrexate in juvenile idiopathic arthritis

por Hinks, Anne, Moncrieffe, Halima, Martin, Paul, Ursu, Simona, Lal, Sham, Kassoumeri, Laura, Weiler, Tracey, Glass, David N, Thompson, Susan D, Wedderburn, Lucy R, Thomson, Wendy
Publicado 2011

Autoinflammatory gene polymorphisms and susceptibility to UK juvenile idiopathic arthritis

por Hinks, Anne, Martin, Paul, Thompson, Susan D, Sudman, Marc, Stock, Carmel J, Thomson, Wendy, Day, Thomas G, Packham, Jon, Ramanan, Athimalaipet V, Donn, Rachelle P
Publicado 2013

Familial autoimmunity in the childhood arthritis and rheumatology research alliance registry

por Prahalad, Sampath, McCracken, Courtney E., Ponder, Lori A., Angeles-Han, Sheila T., Rouster Stevens, Kelly A., Vogler, Larry B., Langefeld, Carl D., Thompson, Susan D.
Publicado 2016

Tapasin gene polymorphism in systemic onset juvenile rheumatoid arthritis: a family-based case–control study

por Bukulmez, Hulya, Fife, Mark, Tsoras, Monica, Thompson, Susan D, Twine, Natalie A, Woo, Patricia, Olson, Jane M, Elston, Robert C, Glass, David N, Colbert, Robert A
Publicado 2005

Investigation of rheumatoid arthritis susceptibility loci in juvenile idiopathic arthritis confirms high degree of overlap

por Hinks, Anne, Cobb, Joanna, Sudman, Marc, Eyre, Stephen, Martin, Paul, Flynn, Edward, Packham, Jonathon, Barton, Anne, Worthington, Jane, Langefeld, Carl D, Glass, David N, Thompson, Susan D, Thomson, Wendy
Publicado 2012

Elevated serum complement levels and higher gene copy number of complement C4B are associated with hypertension and effective response to statin therapy in childhood-onset systemic...

por Mulvihill, Evan, Ardoin, Stacy, Thompson, Susan D, Zhou, Bi, Yu, Gakit Richard, King, Emily, Singer, Nora, Levy, D M, Brunner, Hermine, Wu, Yee Ling, Nagaraja, Haikady N, Schanberg, Laura Eve, Yu, Chack-Yung
Publicado 2019

Platelet Glycoprotein Ib α‐Chain as a Putative Therapeutic Target for Juvenile Idiopathic Arthritis: A Mendelian Randomization Study

por Luo, Shan, Clarke, Sarah L. N., Ramanan, Athimalaipet V., Thompson, Susan D., Langefeld, Carl D., Marion, Miranda C., Grom, Alexei A., Schooling, C. Mary, Gaunt, Tom R., Yeung, Shiu Lun Au, Zheng, Jie
Publicado 2021

Immature cell populations and an erythropoiesis gene-expression signature in systemic juvenile idiopathic arthritis: implications for pathogenesis

por Hinze, Claas H, Fall, Ndate, Thornton, Sherry, Mo, Jun Q, Aronow, Bruce J, Layh-Schmitt, Gerlinde, Griffin, Thomas A, Thompson, Susan D, Colbert, Robert A, Glass, David N, Barnes, Michael G, Grom, Alexei A
Publicado 2010

Juvenile idiopathic arthritis is associated with potentially pathogenic glycosylation of IgG

por Ercan, Altan, Hazen, Melissa, Son, Mary Beth, Kim, Susan, Dedeoglu, Fatma, Sundel, Robert P, Fuhlbrigge, Robert C, Cui, Jing, Shadick, Nancy A, Weinblatt, Michael E, Spigarelli, Michael, Glass, David N, Thompson, Susan D, Nigrovic, Peter A
Publicado 2012

Phenome-wide association study (PheWAS) in EMR-linked pediatric cohorts, genetically links PLCL1 to speech language development and IL5-IL13 to Eosinophilic Esophagitis

por Namjou, Bahram, Marsolo, Keith, Caroll, Robert J., Denny, Joshua C., Ritchie, Marylyn D., Verma, Shefali S., Lingren, Todd, Porollo, Aleksey, Cobb, Beth L., Perry, Cassandra, Kottyan, Leah C., Rothenberg, Marc E., Thompson, Susan D., Holm, Ingrid A., Kohane, Isaac S., Harley, John B.
Publicado 2014

Combined genetic analysis of juvenile idiopathic arthritis clinical subtypes identifies novel risk loci, target genes and key regulatory mechanisms

por López-Isac, Elena, Smith, Samantha L, Marion, Miranda C, Wood, Abigail, Sudman, Marc, Yarwood, Annie, Shi, Chenfu, Gaddi, Vasanthi Priyadarshini, Martin, Paul, Prahalad, Sampath, Eyre, Stephen, Orozco, Gisela, Morris, Andrew P, Langefeld, Carl D, Thompson, Susan D, Thomson, Wendy, Bowes, John
Publicado 2021

Susceptibility to childhood onset rheumatoid arthritis: investigation of a weighted genetic risk score that integrates cumulative effects of five genetic risk variants

por Prahalad, Sampath, Brown, Milton, Thompson, Susan D, Zwick, Michael, Cutler, David, Ponder, Lori A, Prozonic, Jennifer, Angeles-Han, Sheila, Vogler, Larry B, Kennedy, Christine W, Wallace, Carol A, Wise, Carol, Punaro, Marilynn G, Reed, Ann M, Park, Jane L, Mellins, Elizabeth D, Bohnsack, John F, Glass, David N
Publicado 2012

Identification of a regulatory pathway governing TRAF1 via an arthritis-associated non-coding variant

por Wang, Qiang, Martínez-Bonet, Marta, Kim, Taehyeung, Sparks, Jeffrey A., Ishigaki, Kazuyoshi, Chen, Xiaoting, Sudman, Marc, Aguiar, Vitor, Sim, Sangwan, Hernandez, Marcos Chiñas, Chiu, Darren J., Wactor, Alexandra, Wauford, Brian, Marion, Miranda C., Gutierrez-Arcelus, Maria, Bowes, John, Eyre, Stephen, Nordal, Ellen, Prahalad, Sampath, Rygg, Marite, Videm, Vibeke, Raychaudhuri, Soumya, Weirauch, Matthew T., Langefeld, Carl D., Thompson, Susan D., Nigrovic, Peter A.
Publicado 2023

Identification of Novel Loci Shared by Juvenile Idiopathic Arthritis Subtypes Through Integrative Genetic Analysis

por Li, Jin, Li, Yun R., Glessner, Joseph T., Yang, Jie, March, Michael E., Kao, Charlly, Vaccaro, Courtney N., Bradfield, Jonathan P., Li, Junyi, Mentch, Frank D., Qu, Hui‐Qi, Qi, Xiaohui, Chang, Xiao, Hou, Cuiping, Abrams, Debra J., Qiu, Haijun, Wei, Zhi, Connolly, John J., Wang, Fengxiang, Snyder, James, Flatø, Berit, Thompson, Susan D., Langefeld, Carl D., Lie, Benedicte A., Munro, Jane E., Wise, Carol, Sleiman, Patrick M. A., Hakonarson, Hakon
Publicado 2022

Brief Report: The Genetic Profile of Rheumatoid Factor–Positive Polyarticular Juvenile Idiopathic Arthritis Resembles That of Adult Rheumatoid Arthritis

por Hinks, Anne, Marion, Miranda C., Cobb, Joanna, Comeau, Mary E., Sudman, Marc, Ainsworth, Hannah C., Bowes, John, Becker, Mara L., Bohnsack, John F., Haas, Johannes‐Peter, Lovell, Daniel J., Mellins, Elizabeth D., Nelson, J. Lee, Nordal, Ellen, Punaro, Marilynn, Reed, Ann M., Rose, Carlos D., Rosenberg, Alan M., Rygg, Marite, Smith, Samantha L., Stevens, Anne M., Videm, Vibeke, Wallace, Carol A., Wedderburn, Lucy R., Yarwood, Annie, Yeung, Rae S. M., Langefeld, Carl D., Thompson, Susan D., Thomson, Wendy, Prahalad, Sampath
Publicado 2018

Dissecting Allele Architecture of Early Onset IBD Using High-Density Genotyping

por Cutler, David J., Zwick, Michael E., Okou, David T., Prahalad, Sampath, Walters, Thomas, Guthery, Stephen L., Dubinsky, Marla, Baldassano, Robert, Crandall, Wallace V., Rosh, Joel, Markowitz, James, Stephens, Michael, Kellermayer, Richard, Pfefferkorn, Marian, Heyman, Melvin B., LeLeiko, Neal, Mack, David, Moulton, Dedrick, Kappelman, Michael D., Kumar, Archana, Prince, Jarod, Bose, Promita, Mondal, Kajari, Ramachandran, Dhanya, Bohnsack, John F., Griffiths, Anne M., Haberman, Yael, Essers, Jonah, Thompson, Susan D., Aronow, Bruce, Keljo, David J., Hyams, Jeffrey S., Denson, Lee A., Kugathasan, Subra
Publicado 2015