Targeting human CALR‐mutated MPN progenitors with a neoepitope‐directed monoclonal antibody

por Tvorogov, Denis, Thompson‐Peach, Chloe A L, Foßelteder, Johannes, Dottore, Mara, Stomski, Frank, Onnesha, Suraiya A, Lim, Kelly, Moretti, Paul A B, Pitson, Stuart M, Ross, David M, Reinisch, Andreas, Thomas, Daniel, Lopez, Angel F
Publicado 2022

Dysregulated Lipid Synthesis by Oncogenic IDH1 Mutation Is a Targetable Synthetic Lethal Vulnerability

por Thomas, Daniel, Wu, Manhong, Nakauchi, Yusuke, Zheng, Ming, Thompson-Peach, Chloe A.L., Lim, Kelly, Landberg, Niklas, Köhnke, Thomas, Robinson, Nirmal, Kaur, Satinder, Kutyna, Monika, Stafford, Melissa, Hiwase, Devendra, Reinisch, Andreas, Peltz, Gary, Majeti, Ravindra
Publicado 2023

Ceramide-induced integrated stress response overcomes Bcl-2 inhibitor resistance in acute myeloid leukemia

por Lewis, Alexander C., Pope, Victoria S., Tea, Melinda N., Li, Manjun, Nwosu, Gus O., Nguyen, Thao M., Wallington-Beddoe, Craig T., Moretti, Paul A. B., Anderson, Dovile, Creek, Darren J., Costabile, Maurizio, Ali, Saira R., Thompson-Peach, Chloe A. L., Dredge, B. Kate, Bert, Andrew G., Goodall, Gregory J., Ekert, Paul G., Brown, Anna L., D’Andrea, Richard, Robinson, Nirmal, Pitman, Melissa R., Thomas, Daniel, Ross, David M., Gliddon, Briony L., Powell, Jason A., Pitson, Stuart M.
Publicado 2022