The double-edge sword of CRISPR application for in vivo studies

por Thomsen, Martin K.
Publicado 2023

Application of CRISPR for In Vivo Mouse Cancer Studies

por Thomsen, Martin K.
Publicado 2022

Pre-Clinical Models to Study Human Prostate Cancer

por Thomsen, Martin K., Busk, Morten
Publicado 2023

β-Catenin Is Required for Prostate Development and Cooperates with Pten Loss to Drive Invasive Carcinoma

por Francis, Jeffrey C., Thomsen, Martin K., Taketo, Makoto M., Swain, Amanda
Publicado 2013

Brca2 and Trp53 Deficiency Cooperate in the Progression of Mouse Prostate Tumourigenesis

por Francis, Jeffrey C., McCarthy, Afshan, Thomsen, Martin K., Ashworth, Alan, Swain, Amanda
Publicado 2010

Targeting AP-1 transcription factors by CRISPR in the prostate

por Riedel, Maria, Cai, Huiqiang, Stoltze, Iben C., Vendelbo, Mikkel H., Wagner, Erwin F., Bakiri, Latifa, Thomsen, Martin K.
Publicado 2021

In Vivo Application of CRISPR/Cas9 Revealed Implication of Foxa1 and Foxp1 in Prostate Cancer Proliferation and Epithelial Plasticity

por Cai, Huiqiang, Agersnap, Simon N., Sjøgren, Amalie, Simonsen, Mikkel K., Blaavand, Mathilde S., Jensen, Ulrikke V., Thomsen, Martin K.
Publicado 2022

STING agonists enable antiviral cross-talk between human cells and confer protection against genital herpes in mice

por Skouboe, Morten K., Knudsen, Alice, Reinert, Line S., Boularan, Cedric, Lioux, Thierry, Perouzel, Eric, Thomsen, Martin K., Paludan, Søren R.
Publicado 2018

Comparative Analysis of Stk11/Lkb1 versus Pten Deficiency in Lung Adenocarcinoma Induced by CRISPR/Cas9

por Berthelsen, Martin F., Leknes, Siv L., Riedel, Maria, Pedersen, Mette A., Joseph, Justin V., Hager, Henrik, Vendelbo, Mikkel H., Thomsen, Martin K.
Publicado 2021

ER stress induces caspase‐2‐tBID‐GSDME‐dependent cell death in neurons lytically infected with herpes simplex virus type 2

por Ren, Fanghui, Narita, Ryo, Rashidi, Ahmad S, Fruhwürth, Stefanie, Gao, Zongliang, Bak, Rasmus O, Thomsen, Martin K, Verjans, Georges MGM, Reinert, Line S, Paludan, Søren R
Publicado 2023

Liver carcinogenesis by FOS-dependent inflammation and cholesterol dysregulation

por Bakiri, Latifa, Hamacher, Rainer, Graña, Osvaldo, Guío-Carrión, Ana, Campos-Olivas, Ramón, Martinez, Lola, Dienes, Hans P., Thomsen, Martin K., Hasenfuss, Sebastian C., Wagner, Erwin F.
Publicado 2017

In vivo CRISPR inactivation of Fospromotes prostate cancer progression by altering the associated AP-1 subunit Jun

por Riedel, Maria, Berthelsen, Martin F., Cai, Huiqiang, Haldrup, Jakob, Borre, Michael, Paludan, S⌀ren R., Hager, Henrik, Vendelbo, Mikkel H., Wagner, Erwin F., Bakiri, Latifa, Thomsen, Martin K.
Publicado 2021

Sensing of HSV-1 by the cGAS–STING pathway in microglia orchestrates antiviral defence in the CNS

por Reinert, Line S., Lopušná, Katarína, Winther, Henriette, Sun, Chenglong, Thomsen, Martin K., Nandakumar, Ramya, Mogensen, Trine H., Meyer, Morten, Vægter, Christian, Nyengaard, Jens R., Fitzgerald, Katherine A., Paludan, Søren R.
Publicado 2016

Engineered lentivirus-derived nanoparticles (LVNPs) for delivery of CRISPR/Cas ribonucleoprotein complexes supporting base editing, prime editing and in vivo gene modification

por Haldrup, Jakob, Andersen, Sofie, Labial, Alexander Rafael LaVilla, Wolff, Jonas Holst, Frandsen, Frederik Plum, Skov, Thomas Wisbech, Rovsing, Anne Bruun, Nielsen, Ian, Jakobsen, Thomas Stax, Askou, Anne Louise, Thomsen, Martin K, Corydon, Thomas J, Thomsen, Emil Aagaard, Mikkelsen, Jacob Giehm
Publicado 2023

Intracellular bacteria engage a STING-TBK1-MVB12b pathway to enable paracrine cGAS-STING signaling

por Nandakumar, Ramya, Tschismarov, Roland, Meissner, Felix, Prabakaran, Thaneas, Krissanaprasit, Abhichart, Farahani, Ensieh, Zhang, Bao-cun, Assil, Sonia, Martin, Amandine, Bertrams, Wilhelm, Holm, Christian K, Ablasser, Andrea, Klause, Tanja, Thomsen, Martin K, Schmeck, Bernd, Howard, Kenneth A, Henry, Thomas, Gothelf, Kurt V, Decker, Thomas, Paludan, Søren R
Publicado 2019

A genetically inducible porcine model of intestinal cancer

por Callesen, Morten M., Árnadóttir, Sigrid S., Lyskjær, Iben, Ørntoft, Mai‐Britt W., Høyer, Søren, Dagnæs‐Hansen, Frederik, Liu, Ying, Li, Rong, Callesen, Henrik, Rasmussen, Mads H., Berthelsen, Martin F., Thomsen, Martin K., Schweiger, Pawel J., Jensen, Kim B., Laurberg, Søren, Ørntoft, Torben F., Elverløv‐Jakobsen, Jannik E., Andersen, Claus L.
Publicado 2017

Influenza A virus targets a cGAS-independent STING pathway that controls enveloped RNA viruses

por Holm, Christian K., Rahbek, Stine H., Gad, Hans Henrik, Bak, Rasmus O., Jakobsen, Martin R., Jiang, Zhaozaho, Hansen, Anne Louise, Jensen, Simon K., Sun, Chenglong, Thomsen, Martin K., Laustsen, Anders, Nielsen, Camilla G., Severinsen, Kasper, Xiong, Yingluo, Burdette, Dara L., Hornung, Veit, Lebbink, Robert Jan, Duch, Mogens, Fitzgerald, Katherine A., Bahrami, Shervin, Mikkelsen, Jakob Giehm, Hartmann, Rune, Paludan, Søren R.
Publicado 2016

STEEP mediates STING ER exit and activation of signaling

por Zhang, Bao-cun, Nandakumar, Ramya, Reinert, Line S, Huang, Jinrong, Laustsen, Anders, Gao, Zong-liang, Sun, Cheng-long, Jensen, Søren Beck, Troldborg, Anne, Assil, Sonia, Berthelsen, Martin F., Scavenius, Carsten, Zhang, Yan, Windross, Samuel J, Olagnier, David, Prabakaran, Thaneas, Bodda, Chiranjeevi, Narita, Ryo, Cai, Yujia, Zhang, Cong-gang, Stenmark, Harald, Doucet, Christine M, Noda, Takeshi, Guo, Zheng, Goldbach-Mansky, Raphaela, Hartmann, Rune, Chen, Zhijian J, Enghild, Jan J, Bak, Rasmus O, Thomsen, Martin K., Paludan, Søren R
Publicado 2020

Life-threatening viral disease in a novel form of autosomal recessive IFNAR2 deficiency in the Arctic

por Duncan, Christopher J.A., Skouboe, Morten K., Howarth, Sophie, Hollensen, Anne K., Chen, Rui, Børresen, Malene L., Thompson, Benjamin J., Stremenova Spegarova, Jarmila, Hatton, Catherine F., Stæger, Frederik F., Andersen, Mette K., Whittaker, John, Paludan, Søren R., Jørgensen, Sofie E., Thomsen, Martin K., Mikkelsen, Jacob G., Heilmann, Carsten, Buhas, Daniela, Øbro, Nina F., Bay, Jakob T., Marquart, Hanne V., de la Morena, M. Teresa, Klejka, Joseph A., Hirschfeld, Matthew, Borgwardt, Line, Forss, Isabel, Masmas, Tania, Poulsen, Anja, Noya, Francisco, Rouleau, Guy, Hansen, Torben, Zhou, Sirui, Albrechtsen, Anders, Alizadehfar, Reza, Allenspach, Eric J., Hambleton, Sophie, Mogensen, Trine H.
Publicado 2022