Novel Germline Mutations in a Cohort of Men with Familial Prostate Cancer

por Mondschein, Romy, Bolton, Damien, Clouston, David, Dowty, James, Kavanagh, Liam, Murphy, Declan, Scott, Prudence, Taylor, Renea A., Thorne, Heather
Publicado 2022

Multifactorial Likelihood Assessment of BRCA1 and BRCA2 Missense Variants Confirms That BRCA1:c.122A>G(p.His41Arg) Is a Pathogenic Mutation

por Whiley, Phillip J., Parsons, Michael T., Leary, Jennifer, Tucker, Kathy, Warwick, Linda, Dopita, Belinda, Thorne, Heather, Lakhani, Sunil R., Goldgar, David E., Brown, Melissa A., Spurdle, Amanda B.
Publicado 2014

The intronic G13964C variant in p53 is not a high-risk mutation in familial breast cancer in Australia

por Marsh, Anna, Spurdle, Amanda B, Turner, Bruce C, Fereday, Sian, Thorne, Heather, Pupo, Gulietta M, Mann, Graham J, Hopper, John L, Sambrook, Joseph F, Chenevix-Trench, Georgia
Publicado 2001

Weight is More Informative than Body Mass Index for Predicting Postmenopausal Breast Cancer Risk: Prospective Family Study Cohort (ProF-SC)

por Ye, Zhoufeng, Li, Shuai, Dite, Gillian S., Nguyen, Tuong L., MacInnis, Robert J., Andrulis, Irene L., Buys, Saundra S., Daly, Mary B., John, Esther M., Kurian, Allison W., Genkinger, Jeanine M., Chung, Wendy K., Phillips, Kelly-Anne, Thorne, Heather, Thorne, Heather, Winship, Ingrid M., Milne, Roger L., Dugué, Pierre-Antoine, Southey, Melissa C., Giles, Graham G., Terry, Mary Beth, Hopper, John L.
Publicado 2022

Multiple ABCB1 transcriptional fusions in drug resistant high-grade serous ovarian and breast cancer

por Christie, Elizabeth L., Pattnaik, Swetansu, Beach, Jessica, Copeland, Anthony, Rashoo, Nineveh, Fereday, Sian, Hendley, Joy, Alsop, Kathryn, Brady, Samuel L., Lamb, Greg, Pandey, Ahwan, deFazio, Anna, Thorne, Heather, Bild, Andrea, Bowtell, David D. L.
Publicado 2019

“Cancer 2015”: A Prospective, Population-Based Cancer Cohort—Phase 1: Feasibility of Genomics-Guided Precision Medicine in the Clinic

por Parisot, John P., Thorne, Heather, Fellowes, Andrew, Doig, Ken, Lucas, Mark, McNeil, John J., Doble, Brett, Dobrovic, Alexander, John, Thomas, James, Paul A., Lipton, Lara, Ashley, David, Hayes, Theresa, McMurrick, Paul, Richardson, Gary, Lorgelly, Paula, Fox, Stephen B., Thomas, David M.
Publicado 2015

Exome Sequencing Identifies Rare Deleterious Mutations in DNA Repair Genes FANCC and BLM as Potential Breast Cancer Susceptibility Alleles

por Thompson, Ella R., Doyle, Maria A., Ryland, Georgina L., Rowley, Simone M., Choong, David Y. H., Tothill, Richard W., Thorne, Heather, Barnes, Daniel R., Li, Jason, Ellul, Jason, Philip, Gayle K., Antill, Yoland C., James, Paul A., Trainer, Alison H., Mitchell, Gillian, Campbell, Ian G.
Publicado 2012

The Subclonal Architecture of Metastatic Breast Cancer: Results from a Prospective Community-Based Rapid Autopsy Program “CASCADE”

por Savas, Peter, Teo, Zhi Ling, Lefevre, Christophe, Flensburg, Christoffer, Caramia, Franco, Alsop, Kathryn, Mansour, Mariam, Francis, Prudence A., Thorne, Heather A., Silva, Maria Joao, Kanu, Nnennaya, Dietzen, Michelle, Rowan, Andrew, Kschischo, Maik, Fox, Stephen, Bowtell, David D., Dawson, Sarah-Jane, Speed, Terence P., Swanton, Charles, Loi, Sherene
Publicado 2016

Correction: The Subclonal Architecture of Metastatic Breast Cancer: Results from a Prospective Community-Based Rapid Autopsy Program "CASCADE"

por Savas, Peter, Teo, Zhi Ling, Lefevre, Christophe, Flensburg, Christoffer, Caramia, Franco, Alsop, Kathryn, Mansour, Mariam, Francis, Prudence A., Thorne, Heather A., Silva, Maria Joao, Kanu, Nnennaya, Dietzen, Michelle, Rowan, Andrew, Kschischo, Maik, Fox, Stephen, Bowtell, David D., Dawson, Sarah-Jane, Speed, Terence P., Swanton, Charles, Loi, Sherene
Publicado 2017

Clinical Outcome of Prostate Cancer Patients with Germline DNA Repair Mutations: Retrospective Analysis from an International Study

por Mateo, Joaquin, Cheng, Heather H., Beltran, Himisha, Dolling, David, Xu, Wen, Pritchard, Colin C., Mossop, Helen, Rescigno, Pasquale, Perez-Lopez, Raquel, Sailer, Verena, Kolinsky, Michael, Balasopoulou, Ada, Bertan, Claudia, Nanus, David M., Tagawa, Scott T., Thorne, Heather, Montgomery, Bruce, Carreira, Suzanne, Sandhu, Shahneen, Rubin, Mark A., Nelson, Peter S., de Bono, Johann S.
Publicado 2018

Tumor immune microenvironment of primary prostate cancer with and without germline mutations in homologous recombination repair genes

por Trigos, Anna Sofia, Pasam, Anupama, Banks, Patricia, Wallace, Roslyn, Guo, Christina, Keam, Simon, Thorne, Heather, Mitchell, Catherine, Lade, Stephen, Clouston, David, Hakansson, Alexander, Liu, Yang, Blyth, Benjamin, Murphy, Declan, Lawrentschuk, Nathan, Bolton, Damien, Moon, Daniel, Darcy, Phil, Haupt, Ygal, Williams, Scott G, Castro, Elena, Olmos, David, Goode, David, Neeson, Paul, Sandhu, Shahneen
Publicado 2022

Breast cancer risk prediction using a polygenic risk score in the familial setting: a prospective study from the Breast Cancer Family Registry and kConFab

por Li, Hongyan, Feng, Bingjian, Miron, Alexander, Chen, Xiaoqing, Beesley, Jonathan, Bimeh, Emmanuella, Barrowdale, Daniel, John, Esther M., Daly, Mary B., Andrulis, Irene L., Buys, Saundra S., Kraft, Peter, Thorne, Heather, Chenevix-Trench, Georgia, Southey, Melissa, Antoniou, Antonis C., James, Paul A., Terry, Mary Beth, Phillips, Kelly-Anne, Hopper, John L., Mitchell, Gillian, Goldgar, David E.
Publicado 2016

Targeting MDM4 as a Novel Therapeutic Approach in Prostate Cancer Independent of p53 Status

por Mejía-Hernández, Javier Octavio, Raghu, Dinesh, Caramia, Franco, Clemons, Nicholas, Fujihara, Kenji, Riseborough, Thomas, Teunisse, Amina, Jochemsen, Aart G., Abrahmsén, Lars, Blandino, Giovanni, Russo, Andrea, Gamell, Cristina, Fox, Stephen B., Mitchell, Catherine, Takano, Elena A., Byrne, David, Miranda, Panimaya Jeffreena, Saleh, Reem, Thorne, Heather, Sandhu, Shahneen, Williams, Scott G., Keam, Simon P., Haupt, Ygal, Haupt, Sue
Publicado 2022

Value of the loss of heterozygosity to BRCA1 variant classification

por Santana dos Santos, Elizabeth, Spurdle, Amanda B., Carraro, Dirce M., Briaux, Adrien, Southey, Melissa, Torrezan, Giovana, Petitalot, Ambre, Leman, Raphael, Lafitte, Philippe, Meseure, Didier, Driouch, Keltouma, Side, Lucy, Brewer, Carole, Beck, Sarah, Melville, Athalie, Callaway, Alison, Revillion, Françoise, Folgueira, Maria A. A. Koike, Parsons, Michael T., Thorne, Heather, Vincent-Salomon, Anne, Stoppa-Lyonnet, Dominique, Bieche, Ivan, Caputo, Sandrine M., Rouleau, Etienne
Publicado 2022

Analysis of cancer risk and BRCA1 and BRCA2 mutation prevalence in the kConFab familial breast cancer resource

por Mann, Graham J, Thorne, Heather, Balleine, Rosemary L, Butow, Phyllis N, Clarke, Christine L, Edkins, Edward, Evans, Gerda M, Fereday, Sián, Haan, Eric, Gattas, Michael, Giles, Graham G, Goldblatt, Jack, Hopper, John L, Kirk, Judy, Leary, Jennifer A, Lindeman, Geoffrey, Niedermayr, Eveline, Phillips, Kelly-Anne, Picken, Sandra, Pupo, Gulietta M, Saunders, Christobel, Scott, Clare L, Spurdle, Amanda B, Suthers, Graeme, Tucker, Kathy, Chenevix-Trench, Georgia
Publicado 2006

Germline BRCA2 mutations drive prostate cancers with distinct evolutionary trajectories

por Taylor, Renea A., Fraser, Michael, Livingstone, Julie, Espiritu, Shadrielle Melijah G., Thorne, Heather, Huang, Vincent, Lo, Winnie, Shiah, Yu-Jia, Yamaguchi, Takafumi N., Sliwinski, Ania, Horsburgh, Sheri, Meng, Alice, Heisler, Lawrence E., Yu, Nancy, Yousif, Fouad, Papargiris, Melissa, Lawrence, Mitchell G., Timms, Lee, Murphy, Declan G., Frydenberg, Mark, Hopkins, Julia F., Bolton, Damien, Clouston, David, McPherson, John D., van der Kwast, Theodorus, Boutros, Paul C., Risbridger, Gail P., Bristow, Robert G.
Publicado 2017

Evolution of late-stage metastatic melanoma is dominated by aneuploidy and whole genome doubling

por Vergara, Ismael A., Mintoff, Christopher P., Sandhu, Shahneen, McIntosh, Lachlan, Young, Richard J., Wong, Stephen Q., Colebatch, Andrew, Cameron, Daniel L., Kwon, Julia Lai, Wolfe, Rory, Peng, Angela, Ellul, Jason, Dou, Xuelin, Fedele, Clare, Boyle, Samantha, Arnau, Gisela Mir, Raleigh, Jeanette, Hatzimihalis, Athena, Szeto, Pacman, Mooi, Jennifer, Widmer, Daniel S., Cheng, Phil F., Amann, Valerie, Dummer, Reinhard, Hayward, Nicholas, Wilmott, James, Scolyer, Richard A., Cho, Raymond J., Bowtell, David, Thorne, Heather, Alsop, Kathryn, Cordner, Stephen, Woodford, Noel, Leditschke, Jodie, O’Brien, Patricia, Dawson, Sarah-Jane, McArthur, Grant A., Mann, Graham J., Levesque, Mitchell P., Papenfuss, Anthony T., Shackleton, Mark
Publicado 2021

The MURAL collection of prostate cancer patient-derived xenografts enables discovery through preclinical models of uro-oncology

por Risbridger, Gail P., Clark, Ashlee K., Porter, Laura H., Toivanen, Roxanne, Bakshi, Andrew, Lister, Natalie L., Pook, David, Pezaro, Carmel J., Sandhu, Shahneen, Keerthikumar, Shivakumar, Quezada Urban, Rosalia, Papargiris, Melissa, Kraska, Jenna, Madsen, Heather B., Wang, Hong, Richards, Michelle G., Niranjan, Birunthi, O’Dea, Samantha, Teng, Linda, Wheelahan, William, Li, Zhuoer, Choo, Nicholas, Ouyang, John F., Thorne, Heather, Devereux, Lisa, Hicks, Rodney J., Sengupta, Shomik, Harewood, Laurence, Iddawala, Mahesh, Azad, Arun A., Goad, Jeremy, Grummet, Jeremy, Kourambas, John, Kwan, Edmond M., Moon, Daniel, Murphy, Declan G., Pedersen, John, Clouston, David, Norden, Sam, Ryan, Andrew, Furic, Luc, Goode, David L., Frydenberg, Mark, Lawrence, Mitchell G., Taylor, Renea A.
Publicado 2021

Pathology of Tumors Associated With Pathogenic Germline Variants in 9 Breast Cancer Susceptibility Genes

por Mavaddat, Nasim, Dorling, Leila, Carvalho, Sara, Allen, Jamie, González-Neira, Anna, Keeman, Renske, Bolla, Manjeet K., Dennis, Joe, Wang, Qin, Ahearn, Thomas U., Andrulis, Irene L., Beckmann, Matthias W., Behrens, Sabine, Benitez, Javier, Bermisheva, Marina, Blomqvist, Carl, Bogdanova, Natalia V., Bojesen, Stig E., Briceno, Ignacio, Brüning, Thomas, Camp, Nicola J., Campbell, Archie, Castelao, Jose E., Chang-Claude, Jenny, Chanock, Stephen J., Chenevix-Trench, Georgia, Christiansen, Hans, Czene, Kamila, Dörk, Thilo, Eriksson, Mikael, Evans, D. Gareth, Fasching, Peter A., Figueroa, Jonine D., Flyger, Henrik, Gabrielson, Marike, Gago-Dominguez, Manuela, Geisler, Jürgen, Giles, Graham G., Guénel, Pascal, Hadjisavvas, Andreas, Hahnen, Eric, Hall, Per, Hamann, Ute, Hartikainen, Jaana M., Hartman, Mikael, Hoppe, Reiner, Howell, Anthony, Jakubowska, Anna, Jung, Audrey, Khusnutdinova, Elza K., Kristensen, Vessela N., Li, Jingmei, Lim, Swee Ho, Lindblom, Annika, Loizidou, Maria A., Lophatananon, Artitaya, Lubiński, Jan, Madsen, Michael J., Mannermaa, Arto, Manoochehri, Mehdi, Margolin, Sara, Mavroudis, Dimitrios, Milne, Roger L., Mohd Taib, Nur Aishah, Morra, Anna, Muir, Kenneth, Obi, Nadia, Osorio, Ana, Park-Simon, Tjoung-Won, Peterlongo, Paolo, Radice, Paolo, Saloustros, Emmanouil, Sawyer, Elinor J., Schmutzler, Rita K., Shah, Mitul, Sim, Xueling, Southey, Melissa C., Thorne, Heather, Tomlinson, Ian, Torres, Diana, Truong, Thérèse, Yip, Cheng Har, Spurdle, Amanda B., Vreeswijk, Maaike P.G., Dunning, Alison M., García-Closas, Montserrat, Pharoah, Paul D.P., Kvist, Anders, Muranen, Taru A., Nevanlinna, Heli, Teo, Soo Hwang, Devilee, Peter, Schmidt, Marjanka K., Easton, Douglas F.
Publicado 2022

Gene-Expression Profiling of Mucinous Ovarian Tumors and Comparison with Upper and Lower Gastrointestinal Tumors Identifies Markers Associated with Adverse Outcomes

por Meagher, Nicola S., Gorringe, Kylie L., Wakefield, Matthew, Bolithon, Adelyn, Pang, Chi Nam Ignatius, Chiu, Derek S., Anglesio, Michael S., Mallitt, Kylie-Ann, Doherty, Jennifer A., Harris, Holly R., Schildkraut, Joellen M., Berchuck, Andrew, Cushing-Haugen, Kara L., Chezar, Ksenia, Chou, Angela, Tan, Adeline, Alsop, Jennifer, Barlow, Ellen, Beckmann, Matthias W., Boros, Jessica, Bowtell, David D.L., Brand, Alison H., Brenton, James D., Campbell, Ian, Cheasley, Dane, Cohen, Joshua, Cybulski, Cezary, Elishaev, Esther, Erber, Ramona, Farrell, Rhonda, Fischer, Anna, Fu, Zhuxuan, Gilks, Blake, Gill, Anthony J., Gourley, Charlie, Grube, Marcel, Harnett, Paul R., Hartmann, Arndt, Hettiaratchi, Anusha, Høgdall, Claus K., Huzarski, Tomasz, Jakubowska, Anna, Jimenez-Linan, Mercedes, Kennedy, Catherine J., Kim, Byoung-Gie, Kim, Jae-Weon, Kim, Jae-Hoon, Klett, Kayla, Koziak, Jennifer M., Lai, Tiffany, Laslavic, Angela, Lester, Jenny, Leung, Yee, Li, Na, Liauw, Winston, Lim, Belle W.X., Linder, Anna, Lubiński, Jan, Mahale, Sakshi, Mateoiu, Constantina, McInerny, Simone, Menkiszak, Janusz, Minoo, Parham, Mittelstadt, Suzana, Morris, David, Orsulic, Sandra, Park, Sang-Yoon, Pearce, Celeste Leigh, Pearson, John V., Pike, Malcolm C., Quinn, Carmel M., Mohan, Ganendra Raj, Rao, Jianyu, Riggan, Marjorie J., Ruebner, Matthias, Salfinger, Stuart, Scott, Clare L., Shah, Mitul, Steed, Helen, Stewart, Colin J.R., Subramanian, Deepak, Sung, Soseul, Tang, Katrina, Timpson, Paul, Ward, Robyn L., Wiedenhoefer, Rebekka, Thorne, Heather, Cohen, Paul A., Crowe, Philip, Fasching, Peter A., Gronwald, Jacek, Hawkins, Nicholas J., Høgdall, Estrid, Huntsman, David G., James, Paul A., Karlan, Beth Y., Kelemen, Linda E., Kommoss, Stefan, Konecny, Gottfried E., Modugno, Francesmary, Park, Sue K., Staebler, Annette, Sundfeldt, Karin, Wu, Anna H., Talhouk, Aline, Pharoah, Paul D.P., Anderson, Lyndal, DeFazio, Anna, Köbel, Martin, Friedlander, Michael L., Ramus, Susan J.
Publicado 2022