Potential Tumor Suppressor Role for the c-Myb Oncogene in Luminal Breast Cancer

por Thorner, Aaron R., Parker, Joel S., Hoadley, Katherine A., Perou, Charles M.
Publicado 2010

Ultrasensitive profiling of UV-induced mutations identifies thousands of subclinical facial tumors in tuberous sclerosis complex

por Klonowska, Katarzyna, Grevelink, Joannes M., Giannikou, Krinio, Ogorek, Barbara A., Herbert, Zachary T., Thorner, Aaron R., Darling, Thomas N., Moss, Joel, Kwiatkowski, David J.
Publicado 2022

Blood collection in cell-stabilizing tubes does not impact germline DNA quality for pediatric patients

por Wollison, Bruce M., Thai, Edwin, Mckinney, Aimee, Ward, Abigail, Clapp, Andrea, Clinton, Catherine, Nag, Anwesha, Thorner, Aaron R., Gastier-Foster, Julie M., Crompton, Brian D.
Publicado 2017

Genomic Evolution in a Patient With Lung Adenocarcinoma With a Germline EGFR T790M Mutation

por Mäkinen, Netta, Zhou, Meng, Bemus, Meredith, Nevin, Julius, Nag, Anwesha, Chen, Ruthia, Colson, Yolonda L., Thorner, Aaron R., Oxnard, Geoffrey R., Meyerson, Matthew, Sholl, Lynette M.
Publicado 2021

MUC1-C integrates aerobic glycolysis with suppression of oxidative phosphorylation in triple-negative breast cancer stem cells

por Yamashita, Nami, Withers, Henry, Morimoto, Yoshihiro, Bhattacharya, Atrayee, Haratake, Naoki, Daimon, Tatsuaki, Fushimi, Atsushi, Nakashoji, Ayako, Thorner, Aaron R., Isenhart, Emily, Rosario, Spencer, Long, Mark D., Kufe, Donald
Publicado 2023

Spatial Heterogeneity in Large Resected Diffuse Large B-Cell Lymphoma Bulks Analysed by Massively Parallel Sequencing of Multiple Synchronous Biopsies

por Magnes, Teresa, Wagner, Sandro, Thorner, Aaron R., Neureiter, Daniel, Klieser, Eckhard, Rinnerthaler, Gabriel, Weiss, Lukas, Huemer, Florian, Schlick, Konstantin, Zaborsky, Nadja, Steiner, Markus, Greil, Richard, Egle, Alexander, Melchardt, Thomas
Publicado 2021

Src Mutation Induces Acquired Lapatinib Resistance in ERBB2-Amplified Human Gastroesophageal Adenocarcinoma Models

por Hong, Yong Sang, Kim, Jihun, Pectasides, Eirini, Fox, Cameron, Hong, Seung-Woo, Ma, Qiuping, Wong, Gabrielle S., Peng, Shouyong, Stachler, Matthew D., Thorner, Aaron R., Van Hummelen, Paul, Bass, Adam J.
Publicado 2014

Mosaic and Intronic Mutations in TSC1/TSC2 Explain the Majority of TSC Patients with No Mutation Identified by Conventional Testing

por Tyburczy, Magdalena E., Dies, Kira A., Glass, Jennifer, Camposano, Susana, Chekaluk, Yvonne, Thorner, Aaron R., Lin, Ling, Krueger, Darcy, Franz, David N., Thiele, Elizabeth A., Sahin, Mustafa, Kwiatkowski, David J.
Publicado 2015

Circulating Tumor DNA Is Associated with Response and Survival in Patients with Advanced Leiomyosarcoma

por Madanat-Harjuoja, Laura M., Klega, Kelly, Lu, Yao, Shulman, David S., Thorner, Aaron R., Nag, Anwesha, Tap, William D., Reinke, Denise K., Diller, Lisa, Ballman, Karla V., George, Suzanne, Crompton, Brian D.
Publicado 2022

Circulating Tumor DNA as a Biomarker in Patients With Stage III and IV Wilms Tumor: Analysis From a Children's Oncology Group Trial, AREN0533

por Madanat-Harjuoja, Laura M., Renfro, Lindsay A., Klega, Kelly, Tornwall, Brett, Thorner, Aaron R., Nag, Anwesha, Dix, David, Dome, Jeffrey S., Diller, Lisa R., Fernandez, Conrad V., Mullen, Elizabeth A., Crompton, Brian D.
Publicado 2022

Unique, dual-indexed sequencing adapters with UMIs effectively eliminate index cross-talk and significantly improve sensitivity of massively parallel sequencing

por MacConaill, Laura E., Burns, Robert T., Nag, Anwesha, Coleman, Haley A., Slevin, Michael K., Giorda, Kristina, Light, Madelyn, Lai, Kevin, Jarosz, Mirna, McNeill, Matthew S., Ducar, Matthew D., Meyerson, Matthew, Thorner, Aaron R.
Publicado 2018

BreaKmer: detection of structural variation in targeted massively parallel sequencing data using kmers

por Abo, Ryan P., Ducar, Matthew, Garcia, Elizabeth P., Thorner, Aaron R., Rojas-Rudilla, Vanesa, Lin, Ling, Sholl, Lynette M., Hahn, William C., Meyerson, Matthew, Lindeman, Neal I., Van Hummelen, Paul, MacConaill, Laura E.
Publicado 2015

Adverse prognostic impact of the loss of STAG2 protein expression in patients with newly diagnosed localised Ewing sarcoma: A report from the Children’s Oncology Group

por Shulman, David S., Chen, Sonja, Hall, David, Nag, Anwesha, Thorner, Aaron R., Lessnick, Stephen L., Stegmaier, Kimberly, Janeway, Katherine A., DuBois, Steven G., Krailo, Mark D., Barkauskas, Donald A., Church, Alanna J., Crompton, Brian D.
Publicado 2022

Cas9 activates the p53 pathway and selects for p53-inactivating mutations

por Enache, Oana M., Rendo, Veronica, Abdusamad, Mai, Lam, Daniel, Davison, Desiree, Pal, Sangita, Currimjee, Naomi, Hess, Julian, Pantel, Sasha, Nag, Anwesha, Thorner, Aaron R., Doench, John G., Vazquez, Francisca, Beroukhim, Rameen, Golub, Todd R., Ben-David, Uri
Publicado 2020

Clinical and molecular characterization of virus-positive and virus-negative Merkel cell carcinoma

por Starrett, Gabriel J., Thakuria, Manisha, Chen, Tianqi, Marcelus, Christina, Cheng, Jingwei, Nomburg, Jason, Thorner, Aaron R., Slevin, Michael K., Powers, Winslow, Burns, Robert T., Perry, Caitlin, Piris, Adriano, Kuo, Frank C., Rabinowits, Guilherme, Giobbie-Hurder, Anita, MacConaill, Laura E., DeCaprio, James A.
Publicado 2020

Angiomatous meningiomas have a distinct genetic profile with multiple chromosomal polysomies including polysomy of chromosome 5

por Abedalthagafi, Malak S., Merrill, Parker H., Bi, Wenya Linda, Jones, Robert T., Listewnik, Marc L., Ramkissoon, Shakti H., Thorner, Aaron R., Dunn, Ian F., Beroukhim, Rameen, Alexander, Brian M., Brastianos, Priscilla K., Francis, Joshua M., Folkerth, Rebecca D., Ligon, Keith L., Hummelen, Paul Van, Ligon, Azra H., Santagata, Sandro
Publicado 2014

Acquired resistance to combined BET and CDK4/6 inhibition in triple-negative breast cancer

por Ge, Jennifer Y., Shu, Shaokun, Kwon, Mijung, Jovanović, Bojana, Murphy, Katherine, Gulvady, Anushree, Fassl, Anne, Trinh, Anne, Kuang, Yanan, Heavey, Grace A., Luoma, Adrienne, Paweletz, Cloud, Thorner, Aaron R., Wucherpfennig, Kai W., Qi, Jun, Brown, Myles, Sicinski, Piotr, McDonald, Thomas O., Pellman, David, Michor, Franziska, Polyak, Kornelia
Publicado 2020

Hedgehog pathway mutations drive oncogenic transformation in high-risk T-cell acute lymphoblastic leukemia

por Burns, Melissa A., Liao, Zi Wei, Yamagata, Natsuko, Pouliot, Gayle P., Stevenson, Kristen E., Neuberg, Donna S., Thorner, Aaron R., Ducar, Matthew, Silverman, Emily A., Hunger, Stephen P., Loh, Mignon L., Winter, Stuart S., Dunsmore, Kimberly P., Wood, Brent, Devidas, Meenakshi, Harris, Marian H., Silverman, Lewis B., Sallan, Stephen E., Gutierrez, Alejandro
Publicado 2018

BRAF alteration status and the histone H3F3A gene K27M mutation segregate spinal cord astrocytoma histology

por Shankar, Ganesh M., Lelic, Nina, Gill, Corey M., Thorner, Aaron R., Van Hummelen, Paul, Wisoff, Jeffrey H., Loeffler, Jay S., Brastianos, Priscilla K., Shin, John H., Borges, Lawrence F., Butler, William E., Zagzag, David, Brody, Rachel I., Duhaime, Ann-Christine, Taylor, Michael D., Hawkins, Cynthia E., Louis, David N., Cahill, Daniel P., Curry, William T., Meyerson, Matthew
Publicado 2015

Genomic landscape of high-grade meningiomas

por Bi, Wenya Linda, Greenwald, Noah F., Abedalthagafi, Malak, Wala, Jeremiah, Gibson, Will J., Agarwalla, Pankaj K., Horowitz, Peleg, Schumacher, Steven E., Esaulova, Ekaterina, Mei, Yu, Chevalier, Aaron, A. Ducar, Matthew, Thorner, Aaron R., van Hummelen, Paul, O. Stemmer-Rachamimov, Anat, Artyomov, Maksym, Al-Mefty, Ossama, Dunn, Gavin P., Santagata, Sandro, Dunn, Ian F., Beroukhim, Rameen
Publicado 2017