Cell-free cloning of highly expanded CTG repeats by amplification of dimerized expanded repeats

por Osborne, Robert J., Thornton, Charles A.
Publicado 2008

Sex-Related Differences in Gene Expression in Human Skeletal Muscle

por Welle, Stephen, Tawil, Rabi, Thornton, Charles A.
Publicado 2008

Computational method for reducing variance with Affymetrix microarrays

por Welle, Stephen, Brooks, Andrew I, Thornton, Charles A
Publicado 2002

Targeted splice sequencing reveals RNA toxicity and therapeutic response in myotonic dystrophy

por Tanner, Matthew K, Tang, Zhenzhi, Thornton, Charles A
Publicado 2021

Benefits of aerobic exercise in myotonic dystrophy type 1

por Mackenzie, Samuel J., Hamel, Johanna, Thornton, Charles A.
Publicado 2022

Muscle Chloride Channel Dysfunction in Two Mouse Models of Myotonic Dystrophy

por Lueck, John D., Mankodi, Ami, Swanson, Maurice S., Thornton, Charles A., Dirksen, Robert T.
Publicado 2007

Detection of expanded RNA repeats using thermostable group II intron reverse transcriptase

por Carrell, Samuel T, Tang, Zhenzhi, Mohr, Sabine, Lambowitz, Alan M, Thornton, Charles A
Publicado 2018

From dynamic combinatorial ‘hit’ to lead: in vitro and in vivo activity of compounds targeting the pathogenic RNAs that cause myotonic dystrophy

por Ofori, Leslie O., Hoskins, Jason, Nakamori, Masayuki, Thornton, Charles A., Miller, Benjamin L.
Publicado 2012

Biophysical mechanisms for QRS- and QTc-interval prolongation in mice with cardiac expression of expanded CUG-repeat RNA

por Tylock, Kevin M., Auerbach, David S., Tang, Zhen Zhi, Thornton, Charles A., Dirksen, Robert T.
Publicado 2020

Combinatorial chloride and calcium channelopathy in myotonic dystrophy

por Cisco, Lily A., Sipple, Matthew T., Edwards, Katherine M., Thornton, Charles A., Lueck, John D.
Publicado 2023

Sarcolemmal-restricted localization of functional ClC-1 channels in mouse skeletal muscle

por Lueck, John D., Rossi, Ann E., Thornton, Charles A., Campbell, Kevin P., Dirksen, Robert T.
Publicado 2010

Response to the letter: “On the localization of ClC-1 in skeletal muscle fibers”

por Lueck, John D., Rossi, Ann E., Thornton, Charles A., Campbell, Kevin P., Dirksen, Robert T.
Publicado 2011

Detection of Slipped-DNAs at the Trinucleotide Repeats of the Myotonic Dystrophy Type I Disease Locus in Patient Tissues

por Axford, Michelle M., Wang, Yuh-Hwa, Nakamori, Masayuki, Zannis-Hadjopoulos, Maria, Thornton, Charles A., Pearson, Christopher E.
Publicado 2013

Muscleblind-like 1 interacts with RNA hairpins in splicing target and pathogenic RNAs

por Yuan, Yuan, Compton, Sarah A., Sobczak, Krzysztof, Stenberg, Myrna G., Thornton, Charles A., Griffith, Jack D., Swanson, Maurice S.
Publicado 2007

Short antisense-locked nucleic acids (all-LNAs) correct alternative splicing abnormalities in myotonic dystrophy

por Wojtkowiak-Szlachcic, Agnieszka, Taylor, Katarzyna, Stepniak-Konieczna, Ewa, Sznajder, Lukasz J., Mykowska, Agnieszka, Sroka, Joanna, Thornton, Charles A., Sobczak, Krzysztof
Publicado 2015

Dose-Dependent Regulation of Alternative Splicing by MBNL Proteins Reveals Biomarkers for Myotonic Dystrophy

por Wagner, Stacey D., Struck, Adam J., Gupta, Riti, Farnsworth, Dylan R., Mahady, Amy E., Eichinger, Katy, Thornton, Charles A., Wang, Eric T., Berglund, J. Andrew
Publicado 2016

Targeting nuclear RNA for in vivo correction of myotonic dystrophy

por Wheeler, Thurman M., Leger, Andrew J., Pandey, Sanjay K., MacLeod, A. Robert, Nakamori, Masayuki, Cheng, Seng H., Wentworth, Bruce M., Bennett, C. Frank, Thornton, Charles A.
Publicado 2012

Transcriptome alterations in myotonic dystrophy frontal cortex

por Otero, Brittney A., Poukalov, Kiril, Hildebrandt, Ryan P., Thornton, Charles A., Jinnai, Kenji, Fujimura, Harutoshi, Kimura, Takashi, Hagerman, Katharine A., Sampson, Jacinda B., Day, John W., Wang, Eric T.
Publicado 2021

Targeting DMPK with Antisense Oligonucleotide Improves Muscle Strength in Myotonic Dystrophy Type 1 Mice

por Jauvin, Dominic, Chrétien, Jessina, Pandey, Sanjay K., Martineau, Laurie, Revillod, Lucille, Bassez, Guillaume, Lachon, Aline, McLeod, A. Robert, Gourdon, Geneviève, Wheeler, Thurman M., Thornton, Charles A., Bennett, C. Frank, Puymirat, Jack
Publicado 2017

Towards development of a statistical framework to evaluate myotonic dystrophy type 1 mRNA biomarkers in the context of a clinical trial

por Kurkiewicz, Adam, Cooper, Anneli, McIlwaine, Emily, Cumming, Sarah A., Adam, Berit, Krahe, Ralf, Puymirat, Jack, Schoser, Benedikt, Timchenko, Lubov, Ashizawa, Tetsuo, Thornton, Charles A., Rogers, Simon, McClure, John D., Monckton, Darren G.
Publicado 2020