Design of high avidity and low affinity antibodies for in situ control of antibody drug conjugate targeting

por Evans, Reginald, Thurber, Greg M.
Publicado 2022

Quantitative pharmacology in antibody-drug conjugate development: armed antibodies or targeted small molecules?

por Nessler, Ian, Khera, Eshita, Thurber, Greg M.
Publicado 2018

Practical Guide for Quantification of In Vivo Degradation Rates for Therapeutic Proteins with Single-Cell Resolution Using Fluorescence Ratio Imaging

por Nessler, Ian, Cilliers, Cornelius, Thurber, Greg M.
Publicado 2020

Multicolor Fluorescent Intravital Live Microscopy (FILM) for Surgical Tumor Resection in a Mouse Xenograft Model

por Thurber, Greg M., Figueiredo, Jose L., Weissleder, Ralph
Publicado 2009

Mechanistic and quantitative insight into cell surface targeted molecular imaging agent design

por Zhang, Liang, Bhatnagar, Sumit, Deschenes, Emily, Thurber, Greg M.
Publicado 2016

Tracking Antibody Distribution with Near-Infrared Fluorescent Dyes: Impact of Dye Structure and Degree of Labeling on Plasma Clearance

por Cilliers, Cornelius, Nessler, Ian, Christodolu, Nikolas, Thurber, Greg M.
Publicado 2017

Predictive Simulations in Preclinical Oncology to Guide the Translation of Biologics

por Dong, Shujun, Nessler, Ian, Kopp, Anna, Rubahamya, Baron, Thurber, Greg M.
Publicado 2022

Efficient (18)F-Labeling of Synthetic Exendin-4 Analogues for Imaging Beta Cells

por Keliher, Edmund J, Reiner, Thomas, Thurber, Greg M, Upadhyay, Rabi, Weissleder, Ralph
Publicado 2012

Antibody–Drug Conjugate Sacituzumab Govitecan Drives Efficient Tissue Penetration and Rapid Intracellular Drug Release

por Kopp, Anna, Hofsess, Scott, Cardillo, Thomas M., Govindan, Serengulam V., Donnell, Jennifer, Thurber, Greg M.
Publicado 2023

Oral and Subcutaneous Administration of a Near-Infrared Fluorescent Molecular Imaging Agent Detects Inflammation in a Mouse Model of Rheumatoid Arthritis

por Bhatnagar, Sumit, Khera, Eshita, Liao, Jianshan, Eniola, Victoria, Hu, Yongjun, Smith, David E., Thurber, Greg M.
Publicado 2019

Oral Administration and Detection of a Near-Infrared Molecular Imaging Agent in an Orthotopic Mouse Model for Breast Cancer Screening

por Bhatnagar, Sumit, Verma, Kirti Dhingra, Hu, Yongjun, Khera, Eshita, Priluck, Aaron, Smith, David E., Thurber, Greg M.
Publicado 2018

Generation of DAR1 Antibody-Drug Conjugates for Ultrapotent Payloads Using Tailored GlycoConnect Technology

por de Bever, Laureen, Popal, Sorraya, van Schaik, Jord, Rubahamya, Baron, van Delft, Floris L., Thurber, Greg M., van Berkel, Sander S.
Publicado 2023

Co-administered antibody improves penetration of antibody–dye conjugate into human cancers with implications for antibody–drug conjugates

por Lu, Guolan, Nishio, Naoki, van den Berg, Nynke S., Martin, Brock A., Fakurnejad, Shayan, van Keulen, Stan, Colevas, Alexander D., Thurber, Greg M., Rosenthal, Eben L.
Publicado 2020

Quantifying ADC bystander payload penetration with cellular resolution using pharmacodynamic mapping

por Khera, Eshita, Cilliers, Cornelius, Smith, Michael D., Ganno, Michelle L., Lai, Katharine C., Keating, Thomas A., Kopp, Anna, Nessler, Ian, Abu-Yousif, Adnan O., Thurber, Greg M.
Publicado 2020

Tumor Drug Penetration Measurements Could Be the Neglected Piece of the Personalized Cancer Treatment Puzzle

por Bartelink, Imke H., Jones, Ella F., Shahidi‐Latham, Sheerin K., Lee, Pei Rong Evelyn, Zheng, Yanan, Vicini, Paolo, van ‘t Veer, Laura, Wolf, Denise, Iagaru, Andrei, Kroetz, Deanna L., Prideaux, Brendan, Cilliers, Cornelius, Thurber, Greg M., Wimana, Zena, Gebhart, Geraldine
Publicado 2018