Therapeutic Cancer Vaccination with Ex Vivo RNA-Transfected Dendritic Cells—An Update

por Dörrie, Jan, Schaft, Niels, Schuler, Gerold, Schuler-Thurner, Beatrice
Publicado 2020

Immunogenic and tolerogenic effects of the chimeric IL-2-diphtheria toxin cytocidal agent Ontak(®) on CD25(+) cells

por Lutz, Manfred B, Baur, Andreas S, Schuler-Thurner, Beatrice, Schuler, Gerold
Publicado 2014

Arming T Cells with a gp100-Specific TCR and a CSPG4-Specific CAR Using Combined DNA- and RNA-Based Receptor Transfer

por Simon, Bianca, Harrer, Dennis C., Schuler-Thurner, Beatrice, Schuler, Gerold, Uslu, Ugur
Publicado 2019

Blood Eosinophilia Is an on-Treatment Biomarker in Patients with Solid Tumors Undergoing Dendritic Cell Vaccination with Autologous Tumor-RNA

por Moreira, Alvaro, Erdmann, Michael, Uslu, Ugur, Vass, Verona, Schuler, Gerold, Schuler-Thurner, Beatrice
Publicado 2020

Clinical-Scale Production of CAR-T Cells for the Treatment of Melanoma Patients by mRNA Transfection of a CSPG4-Specific CAR under Full GMP Compliance

por Wiesinger, Manuel, März, Johannes, Kummer, Mirko, Schuler, Gerold, Dörrie, Jan, Schuler-Thurner, Beatrice, Schaft, Niels
Publicado 2019

A One-Armed Phase I Dose Escalation Trial Design: Personalized Vaccination with IKKβ-Matured, RNA-Loaded Dendritic Cells for Metastatic Uveal Melanoma

por Koch, Elias A. T., Schaft, Niels, Kummer, Mirko, Berking, Carola, Schuler, Gerold, Hasumi, Kenichiro, Dörrie, Jan, Schuler-Thurner, Beatrice
Publicado 2022

The Generation of CAR-Transfected Natural Killer T Cells for the Immunotherapy of Melanoma

por Simon, Bianca, Wiesinger, Manuel, März, Johannes, Wistuba-Hamprecht, Kilian, Weide, Benjamin, Schuler-Thurner, Beatrice, Schuler, Gerold, Dörrie, Jan, Uslu, Ugur
Publicado 2018

The future of affordable cancer immunotherapy

por Schaft, Niels, Dörrie, Jan, Schuler, Gerold, Schuler-Thurner, Beatrice, Sallam, Husam, Klein, Shiri, Eisenberg, Galit, Frankenburg, Shoshana, Lotem, Michal, Khatib, Areej
Publicado 2023

Hypertonicity-enforced BCL-2 addiction unleashes the cytotoxic potential of death receptors

por Sirtl, Simon, Knoll, Gertrud, Trinh, Dieu Thuy, Lang, Isabell, Siegmund, Daniela, Gross, Stefanie, Schuler-Thurner, Beatrice, Neubert, Patrick, Jantsch, Jonathan, Wajant, Harald, Ehrenschwender, Martin
Publicado 2018

Rapid Induction of Tumor-specific Type 1 T Helper Cells in Metastatic Melanoma Patients by Vaccination with Mature, Cryopreserved, Peptide-loaded Monocyte-derived Dendritic Cells

por Schuler-Thurner, Beatrice, Schultz, Erwin S., Berger, Thomas G., Weinlich, Georg, Ebner, Susanne, Woerl, Petra, Bender, Armin, Feuerstein, Bernadette, Fritsch, Peter O., Romani, Nikolaus, Schuler, Gerold
Publicado 2002

Preclinical evaluation of NF-κB-triggered dendritic cells expressing the viral oncogenic driver of Merkel cell carcinoma for therapeutic vaccination

por Gerer, Kerstin F., Erdmann, Michael, Hadrup, Sine R., Lyngaa, Rikke, Martin, Lena-Marie, Voll, Reinhard E., Schuler-Thurner, Beatrice, Schuler, Gerold, Schaft, Niels, Hoyer, Stefanie, Dörrie, Jan
Publicado 2017

Conventional and three-dimensional photography as a tool to map distribution patterns of in-transit melanoma metastases on the lower extremity

por Müller, Kilian, Berking, Carola, Voskens, Caroline, Heppt, Markus V., Heinzerling, Lucie, Koch, Elias A. T., Kramer, Rafaela, Merkel, Susanne, Schuler-Thurner, Beatrice, Schellerer, Vera, Steeb, Theresa, Wessely, Anja, Erdmann, Michael
Publicado 2023

Good Manufacturing Practice-Compliant Production and Lot-Release of Ex Vivo Expanded Regulatory T Cells As Basis for Treatment of Patients with Autoimmune and Inflammatory Disorder...

por Wiesinger, Manuel, Stoica, Diane, Roessner, Susanne, Lorenz, Carmen, Fischer, Anika, Atreya, Raja, Neufert, Clemens F., Atreya, Imke, Scheffold, Alexander, Schuler-Thurner, Beatrice, Neurath, Markus F., Schuler, Gerold, Voskens, Caroline J.
Publicado 2017

Generation of an Oncolytic Herpes Simplex Virus 1 Expressing Human MelanA

por Boscheinen, Jan B., Thomann, Sabrina, Knipe, David M., DeLuca, Neal, Schuler-Thurner, Beatrice, Gross, Stefanie, Dörrie, Jan, Schaft, Niels, Bach, Christian, Rohrhofer, Anette, Werner-Klein, Melanie, Schmidt, Barbara, Schuster, Philipp
Publicado 2019

Safety and tolerability of a single infusion of autologous ex vivo expanded regulatory T cells in adults with ulcerative colitis (ER-TREG 01): protocol of a phase 1, open-label, fa...

por Voskens, Caroline J, Stoica, Diane, Roessner, Susanne, Vitali, Francesco, Zundler, Sebastian, Rosenberg, Marita, Wiesinger, Manuel, Wunder, Jutta, Siegmund, Britta, Schuler-Thurner, Beatrice, Schuler, Gerold, Berking, Carola, Atreya, Raja, Neurath, Markus F
Publicado 2021

Vaccination with Mage-3a1 Peptide–Pulsed Mature, Monocyte-Derived Dendritic Cells Expands Specific Cytotoxic T Cells and Induces Regression of Some Metastases in Advanced Stage IV...

por Thurner, Beatrice, Haendle, Ina, Röder, Claudia, Dieckmann, Detlef, Keikavoussi, Petra, Jonuleit, Helmut, Bender, Armin, Maczek, Christian, Schreiner, Doris, von den Driesch, Peter, Bröcker, Eva B., Steinman, Ralph M., Enk, Alexander, Kämpgen, Eckhart, Schuler, Gerold
Publicado 1999

Nectin-1 Expression Correlates with the Susceptibility of Malignant Melanoma to Oncolytic Herpes Simplex Virus In Vitro and In Vivo

por Schwertner, Barbara, Lindner, Georg, Toledo Stauner, Camila, Klapproth, Elisa, Magnus, Clara, Rohrhofer, Anette, Gross, Stefanie, Schuler-Thurner, Beatrice, Öttl, Veronika, Feichtgruber, Nicole, Drexler, Konstantin, Evert, Katja, Krahn, Michael P., Berneburg, Mark, Schmidt, Barbara, Schuster, Philipp, Haferkamp, Sebastian
Publicado 2021

Autologous regulatory T-cell transfer in refractory ulcerative colitis with concomitant primary sclerosing cholangitis

por Voskens, Caroline, Stoica, Diane, Rosenberg, Marita, Vitali, Francesco, Zundler, Sebastian, Ganslmayer, Marion, Knott, Heike, Wiesinger, Manuel, Wunder, Jutta, Kummer, Mirko, Siegmund, Britta, Schnoy, Elisabeth, Rath, Timo, Hartmann, Arndt, Hackstein, Holger, Schuler-Thurner, Beatrice, Berking, Carola, Schuler, Gerold, Atreya, Raja, Neurath, Markus F
Publicado 2023

Clinical determinants of long-term survival in metastatic uveal melanoma

por Koch, Elias A. T., Petzold, Anne, Wessely, Anja, Dippel, Edgar, Erdmann, Michael, Heinzerling, Lucie, Hohberger, Bettina, Knorr, Harald, Leiter, Ulrike, Meier, Friedegund, Mohr, Peter, Rahimi, Farnaz, Schell, Beatrice, Schlaak, Max, Terheyden, Patrick, Schuler-Thurner, Beatrice, Ugurel, Selma, Utikal, Jochen, Vera, Julio, Weichenthal, Michael, Ziller, Fabian, Berking, Carola, Heppt, Markus V.
Publicado 2021

Survival of metastatic melanoma patients after dendritic cell vaccination correlates with expression of leukocyte phosphatidylethanolamine-binding protein 1/Raf kinase inhibitory p...

por Buschow, Sonja I., Ramazzotti, Matteo, Reinieren-Beeren, Inge M.J., Heinzerling, Lucie M., Westdorp, Harm, Stefanini, Irene, Beltrame, Luca, Hato, Stanleyson V., Ellebaek, Eva, Gross, Stefanie, Nguyen, Van Anh, Weinlich, Georg, Ragoussis, Jiannis, Baban, Dilair, Schuler-Thurner, Beatrice, Svane, Inge M., Romani, Nikolaus, Austyn, Jonathan M., De Vries, I. Jolanda M., Schuler, Gerold, Cavalieri, Duccio, Figdor, Carl G.
Publicado 2017