Comparative analysis of N-terminal cysteine dioxygenation and prolyl-hydroxylation as oxygen-sensing pathways in mammalian cells

por Tian, Ya-Min, Holdship, Philip, To, Trang Quynh, Ratcliffe, Peter J., Keeley, Thomas P.
Publicado 2023

Heterogeneous Effects of Direct Hypoxia Pathway Activation in Kidney Cancer

por Salama, Rafik, Masson, Norma, Simpson, Peter, Sciesielski, Lina Katrin, Sun, Min, Tian, Ya-Min, Ratcliffe, Peter John, Mole, David Robert
Publicado 2015

The FIH hydroxylase is a cellular peroxide sensor that modulates HIF transcriptional activity

por Masson, Norma, Singleton, Rachelle S, Sekirnik, Rok, Trudgian, David C, Ambrose, Lucy J, Miranda, Melroy X, Tian, Ya-Min, Kessler, Benedikt M, Schofield, Christopher J, Ratcliffe, Peter J
Publicado 2012

Lack of activity of recombinant HIF prolyl hydroxylases (PHDs) on reported non-HIF substrates

por Cockman, Matthew E, Lippl, Kerstin, Tian, Ya-Min, Pegg, Hamish B, Figg, William D, Abboud, Martine I, Heilig, Raphael, Fischer, Roman, Myllyharju, Johanna, Schofield, Christopher J, Ratcliffe, Peter J
Publicado 2019

Differential Sensitivity of Hypoxia Inducible Factor Hydroxylation Sites to Hypoxia and Hydroxylase Inhibitors

por Tian, Ya-Min, Yeoh, Kar Kheng, Lee, Myung Kyu, Eriksson, Tuula, Kessler, Benedikt M., Kramer, Holger B., Edelmann, Mariola J., Willam, Carsten, Pugh, Christopher W., Schofield, Christopher J., Ratcliffe, Peter J.
Publicado 2011

Integrated analysis of microRNA and mRNA expression and association with HIF binding reveals the complexity of microRNA expression regulation under hypoxia

por Camps, Carme, Saini, Harpreet K, Mole, David R, Choudhry, Hani, Reczko, Martin, Guerra-Assunção, José Afonso, Tian, Ya-Min, Buffa, Francesca M, Harris, Adrian L, Hatzigeorgiou, Artemis G, Enright, Anton J, Ragoussis, Jiannis
Publicado 2014

Structural basis for oxygen degradation domain selectivity of the HIF prolyl hydroxylases

por Chowdhury, Rasheduzzaman, Leung, Ivanhoe K. H., Tian, Ya-Min, Abboud, Martine I., Ge, Wei, Domene, Carmen, Cantrelle, François-Xavier, Landrieu, Isabelle, Hardy, Adam P., Pugh, Christopher W., Ratcliffe, Peter J., Claridge, Timothy D. W., Schofield, Christopher J.
Publicado 2016

Potent and Selective Triazole-Based Inhibitors of the Hypoxia-Inducible Factor Prolyl-Hydroxylases with Activity in the Murine Brain

por Chan, Mun Chiang, Atasoylu, Onur, Hodson, Emma, Tumber, Anthony, Leung, Ivanhoe K. H., Chowdhury, Rasheduzzaman, Gómez-Pérez, Verónica, Demetriades, Marina, Rydzik, Anna M., Holt-Martyn, James, Tian, Ya-Min, Bishop, Tammie, Claridge, Timothy D. W., Kawamura, Akane, Pugh, Christopher W., Ratcliffe, Peter J., Schofield, Christopher J.
Publicado 2015

Evaluation of orelabrutinib monotherapy in patients with relapsed or refractory Waldenström's macroglobulinemia in a single-arm, multicenter, open-label, phase 2 study

por Cao, Xin-xin, Jin, Jie, Fu, Cheng-cheng, Yi, Shu-hua, Zhao, Wei-li, Sun, Zi-min, Yang, Wei, Li, Deng-ju, Cui, Guo-hui, Hu, Jian-da, Liu, Ting, Song, Yong-ping, Xu, Bing, Zhu, Zun-min, Xu, Wei, Zhang, Ming-zhi, Tian, Ya-min, Zhang, Bin, Zhao, Ren-bin, Zhou, Dao-bin
Publicado 2022

Orelabrutinib for the treatment of relapsed or refractory MCL: a phase 1/2, open-label, multicenter, single-arm study

por Deng, Li-Juan, Zhou, Ke-Shu, Liu, Li-Hong, Zhang, Ming-Zhi, Li, Zhi-Ming, Ji, Chun-Yan, Xu, Wei, Liu, Ting, Xu, Bing, Wang, Xin, Gao, Su-Jun, Zhang, Hui-Lai, Hu, Yu, Li, Yan, Cheng, Ying, Yang, Hai-Yan, Cao, Jun-Ning, Zhu, Zun-Min, Hu, Jian-Da, Zhang, Wei, Jing, Hong-Mei, Ding, Kai-Yang, Zhang, Xiang-Yang, Zhao, Ren-Bin, Zhang, Bin, Tian, Ya-Min, Song, Yong-Ping, Song, Yu-Qin, Zhu, Jun
Publicado 2023