Combined 3D-QSAR and Docking Modelling Study on Indolocarbazole Series Compounds as Tie-2 Inhibitors

por Tian, Yuanxin, Xu, Jian, Li, Zhonghuang, Zhu, Zhengguang, Zhang, Jiajie, Wu, Shuguang
Publicado 2011

Probing the Behaviour of Cas1-Cas2 upon Protospacer Binding in CRISPR-Cas Systems using Molecular Dynamics Simulations

por Wan, Hua, Li, Jianming, Chang, Shan, Lin, Shuoxin, Tian, Yuanxin, Tian, Xuhong, Wang, Meihua, Hu, Jianping
Publicado 2019

Mutation in Transmembrane Domain 8 of Human Urate Transporter 1 Disrupts Uric Acid Recognition and Transport

por Lan, Qunsheng, Zhao, Ze’an, Liao, Hui, Zheng, Fengxin, Chen, Yongjun, Wu, Ting, Tian, Yuanxin, Pang, Jianxin
Publicado 2022

N-Substituted Pyrrole Derivative 12m Inhibits HIV-1 Entry by Targeting Gp41 of HIV-1 Envelope Glycoprotein

por Qiu, Jiayin, Liang, Taizhen, Wu, Junyan, Yu, Fei, He, Xiaoyang, Tian, Yuanxin, Xie, Lan, Jiang, Shibo, Liu, Shuwen, Li, Lin
Publicado 2019

Discovery of novel 2-aminopyridine derivatives as ROS1 and ALK dual inhibitors to combat drug-resistant mutants including ROS1(G2032R) and ALK(G1202R)

por Liu, Siming, Huang, Chuan, Huang, Chunhui, Huang, Yaqi, Yu, Yonghuan, Wu, Guowu, Guo, Fengqiu, Jiang, Ying, Wan, Shanhe, Zhu, Zhengguang, Tian, Yuanxin, Zhu, Jianghua, Zhang, Jiajie
Publicado 2023

Structural Insights into the Atomistic Mechanisms of Uric Acid Recognition and Translocation of Human Urate Anion Transporter 1

por Zhao, Ze’an, Jiang, Yu, Li, Lu, Chen, Yanyu, Li, Yongmei, Lan, Qunsheng, Wu, Ting, Lin, Cuiting, Cao, Ying, Nandakumar, Kutty Selva, Zhou, Pingzheng, Tian, Yuanxin, Pang, Jianxin
Publicado 2020

The gut microbial metabolite, 3,4-dihydroxyphenylpropionic acid, alleviates hepatic ischemia/reperfusion injury via mitigation of macrophage pro-inflammatory activity in mice

por Li, Rui, Xie, Li, Li, Lei, Chen, Xiaojiao, Yao, Tong, Tian, Yuanxin, Li, Qingping, Wang, Kai, Huang, Chenyang, Li, Cui, Li, Yifan, Zhou, Hongwei, Kaplowitz, Neil, Jiang, Yong, Chen, Peng
Publicado 2022