InVivo Loss of Function Screening Reveals Carbonic Anhydrase IX as a Key Modulator of Tumor Initiating Potential in Primary Pancreatic Tumors()()

por Pore, Nabendu, Jalla, Sanjoo, Liu, Zheng, Higgs, Brandon, Sorio, Claudio, Scarpa, Aldo, Hollingsworth, Robert, Tice, David A., Michelotti, Emil
Publicado 2015

Patient-derived xenograft (PDX) tumors increase growth rate with time

por Pearson, Alexander T., Finkel, Kelsey A., Warner, Kristy A., Nör, Felipe, Tice, David, Martins, Manoela D., Jackson, Trachette L., Nör, Jacques E.
Publicado 2016

MEDI3039, a novel highly potent tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) receptor 2 agonist, causes regression of orthotopic tumors and inhibits outgro...

por Greer, Yoshimi Endo, Gilbert, Samuel F., Gril, Brunilde, Narwal, Rajesh, Peacock Brooks, Danielle L., Tice, David A., Steeg, Patricia S., Lipkowitz, Stanley
Publicado 2019

Preclinical Efficacy of BCMA-Directed CAR T Cells Incorporating a Novel D Domain Antigen Recognition Domain

por Buonato, Janine M., Edwards, Justin P., Zaritskaya, Liubov, Witter, Alexandra R., Gupta, Ankit, LaFleur, David W., Tice, David A., Richman, Laura K., Hilbert, David M.
Publicado 2022

IL-6 Inhibition With MEDI5117 Decreases The Fraction of Head and Neck Cancer Stem Cells and Prevents Tumor Recurrence()()

por Finkel, Kelsey A., Warner, Kristy A., Kerk, Samuel, Bradford, Carol R., McLean, Scott A., Prince, Mark E., Zhong, Haihong, Hurt, Elaine M., Hollingsworth, Robert E., Wicha, Max S., Tice, David A., Nör, Jacques E.
Publicado 2016

Preclinical evaluation of a GFRA1 targeted antibody-drug conjugate in breast cancer

por Bosco, Emily E., Christie, R. James, Carrasco, Rosa, Sabol, Darrin, Zha, Jiping, DaCosta, Karma, Brown, Lee, Kennedy, Maureen, Meekin, John, Phipps, Sandrina, Ayriss, Joanne, Du, Qun, Bezabeh, Binyam, Chowdhury, Partha, Breen, Shannon, Chen, Cui, Reed, Molly, Hinrichs, MaryJane, Zhong, Haihong, Xiao, Zhan, Dixit, Rakesh, Herbst, Ronald, Tice, David A.
Publicado 2018

Functional Genomic Identification of Predictors of Sensitivity and Mechanisms of Resistance to Multivalent Second-Generation TRAIL-R2 Agonists

por Grinkevitch, Vera, Wappett, Mark, Crawford, Nyree, Price, Stacey, Lees, Andrea, McCann, Christopher, McAllister, Katherine, Prehn, Jochen, Young, Jamie, Bateson, Jess, Gallagher, Lewis, Michaut, Magali, Iyer, Vivek, Chatzipli, Aikaterini, Barthorpe, Syd, Ciznadija, Daniel, Sloma, Ido, Wesa, Amy, Tice, David A., Wessels, Lodewyk, Garnett, Mathew, Longley, Daniel B., McDermott, Ultan, McDade, Simon S.
Publicado 2022

Loss of functional BAP1 augments sensitivity to TRAIL in cancer cells

por Kolluri, Krishna Kalyan, Alifrangis, Constantine, Kumar, Neelam, Ishii, Yuki, Price, Stacey, Michaut, Magali, Williams, Steven, Barthorpe, Syd, Lightfoot, Howard, Busacca, Sara, Sharkey, Annabel, Yuan, Zhenqiang, Sage, Elizabeth K, Vallath, Sabarinath, Le Quesne, John, Tice, David A, Alrifai, Doraid, von Karstedt, Sylvia, Montinaro, Antonella, Guppy, Naomi, Waller, David A, Nakas, Apostolos, Good, Robert, Holmes, Alan, Walczak, Henning, Fennell, Dean A, Garnett, Mathew, Iorio, Francesco, Wessels, Lodewyk, McDermott, Ultan, Janes, Samuel M
Publicado 2018

Genomic Landscape Survey Identifies SRSF1 as a Key Oncodriver in Small Cell Lung Cancer

por Jiang, Liyan, Huang, Jiaqi, Higgs, Brandon W., Hu, Zhibin, Xiao, Zhan, Yao, Xin, Conley, Sarah, Zhong, Haihong, Liu, Zheng, Brohawn, Philip, Shen, Dong, Wu, Song, Ge, Xiaoxiao, Jiang, Yue, Zhao, Yizhuo, Lou, Yuqing, Morehouse, Chris, Zhu, Wei, Sebastian, Yinong, Czapiga, Meggan, Oganesyan, Vaheh, Fu, Haihua, Niu, Yanjie, Zhang, Wei, Streicher, Katie, Tice, David, Zhao, Heng, Zhu, Meng, Xu, Lin, Herbst, Ronald, Su, Xinying, Gu, Yi, Li, Shyoung, Huang, Lihua, Gu, Jianren, Han, Baohui, Jallal, Bahija, Shen, Hongbing, Yao, Yihong
Publicado 2016