Improving the Human Hazard Characterization of Chemicals: A Tox21 Update

por Tice, Raymond R., Austin, Christopher P., Kavlock, Robert J., Bucher, John R.
Publicado 2013

Comparison of Points of Departure for Health Risk Assessment Based on High-Throughput Screening Data

por Sand, Salomon, Parham, Fred, Portier, Christopher J., Tice, Raymond R., Krewski, Daniel
Publicado 2016

Endocrine-Disrupting Chemicals (EDCs): In Vitro Mechanism of Estrogenic Activation and Differential Effects on ER Target Genes

por Li, Yin, Luh, Colin J., Burns, Katherine A., Arao, Yukitomo, Jiang, Zhongliang, Teng, Christina T., Tice, Raymond R., Korach, Kenneth S.
Publicado 2013

RNA-Seq Profiling Reveals Novel Hepatic Gene Expression Pattern in Aflatoxin B1 Treated Rats

por Merrick, B. Alex, Phadke, Dhiral P., Auerbach, Scott S., Mav, Deepak, Stiegelmeyer, Suzy M., Shah, Ruchir R., Tice, Raymond R.
Publicado 2013

Real-time cell toxicity profiling of Tox21 10K compounds reveals cytotoxicity dependent toxicity pathway linkage

por Hsieh, Jui-Hua, Huang, Ruili, Lin, Ja-An, Sedykh, Alexander, Zhao, Jinghua, Tice, Raymond R., Paules, Richard S., Xia, Menghang, Auerbach, Scott S.
Publicado 2017

Correction: Real-time cell toxicity profiling of Tox21 10K compounds reveals cytotoxicity dependent toxicity pathway linkage

por Hsieh, Jui-Hua, Huang, Ruili, Lin, Ja-An, Sedykh, Alexander, Zhao, Jinghua, Tice, Raymond R., Paules, Richard S., Xia, Menghang, Auerbach, Scott S.
Publicado 2017

Profiling of the Tox21 Chemical Collection for Mitochondrial Function to Identify Compounds that Acutely Decrease Mitochondrial Membrane Potential

por Attene-Ramos, Matias S., Huang, Ruili, Michael, Sam, Witt, Kristine L., Richard, Ann, Tice, Raymond R., Simeonov, Anton, Austin, Christopher P., Xia, Menghang
Publicado 2014

Profiling Environmental Chemicals for Activity in the Antioxidant Response Element Signaling Pathway Using a High Throughput Screening Approach

por Shukla, Sunita J, Huang, Ruili, Simmons, Steven O, Tice, Raymond R, Witt, Kristine L, VanLeer, Danielle, Ramabhadran, Ram, Austin, Christopher P, Xia, Menghang
Publicado 2012

A High-Throughput Approach to Identify Specific Neurotoxicants / Developmental Toxicants in Human Neuronal Cell Function Assays

por Delp, Johannes, Gutbier, Simon, Klima, Stefanie, Hoelting, Lisa, Pinto-Gil, Kevin, Hsieh, Jui-Hua, Aichem, Michael, Klein, Karsten, Schreiber, Falk, Tice, Raymond R., Pastor, Manuel, Behl, Mamta, Leist, Marcel
Publicado 2018

Compound Cytotoxicity Profiling Using Quantitative High-Throughput Screening

por Xia, Menghang, Huang, Ruili, Witt, Kristine L., Southall, Noel, Fostel, Jennifer, Cho, Ming-Hsuang, Jadhav, Ajit, Smith, Cynthia S., Inglese, James, Portier, Christopher J., Tice, Raymond R., Austin, Christopher P.
Publicado 2008

Results of in vitro and in vivo genetic toxicity tests on methyl isocyanate

por Shelby, Michael D., Allen, James W., Caspary, William J., Haworth, Steven, Ivett, James, Kligerman, Andrew, Luke, Carol A., Mason, James M., Myhr, Brian, Tice, Raymond R., Valencia, Ruby, Zeiger, Errol
Publicado 1987

Chemical Genomics Profiling of Environmental Chemical Modulation of Human Nuclear Receptors

por Huang, Ruili, Xia, Menghang, Cho, Ming-Hsuang, Sakamuru, Srilatha, Shinn, Paul, Houck, Keith A., Dix, David J., Judson, Richard S., Witt, Kristine L., Kavlock, Robert J., Tice, Raymond R., Austin, Christopher P.
Publicado 2011

In silico approaches in carcinogenicity hazard assessment: case study of pregabalin, a nongenotoxic mouse carcinogen

por Keller, Douglas A., Bassan, Arianna, Amberg, Alexander, Burns Naas, Leigh Ann, Chambers, Jon, Cross, Kevin, Hall, Frances, Jahnke, Gloria D., Luniwal, Amarjit, Manganelli, Serena, Mestres, Jordi, Mihalchik-Burhans, Amy L., Woolley, David, Tice, Raymond R.
Publicado 2023

Evaluation of the genotoxicity of cell phone radiofrequency radiation in male and female rats and mice following subchronic exposure

por Smith‐Roe, Stephanie L., Wyde, Michael E., Stout, Matthew D., Winters, John W., Hobbs, Cheryl A., Shepard, Kim G., Green, Amanda S., Kissling, Grace E., Shockley, Keith R., Tice, Raymond R., Bucher, John R., Witt, Kristine L.
Publicado 2019

Population-Based in Vitro Hazard and Concentration–Response Assessment of Chemicals: The 1000 Genomes High-Throughput Screening Study

por Abdo, Nour, Xia, Menghang, Brown, Chad C., Kosyk, Oksana, Huang, Ruili, Sakamuru, Srilatha, Zhou, Yi-Hui, Jack, John R., Gallins, Paul, Xia, Kai, Li, Yun, Chiu, Weihsueh A., Motsinger-Reif, Alison A., Austin, Christopher P., Tice, Raymond R., Rusyn, Ivan, Wright, Fred A.
Publicado 2015

Mitochondria, Energetics, Epigenetics, and Cellular Responses to Stress

por Shaughnessy, Daniel T., McAllister, Kimberly, Worth, Leroy, Haugen, Astrid C., Meyer, Joel N., Domann, Frederick E., Van Houten, Bennett, Mostoslavsky, Raul, Bultman, Scott J., Baccarelli, Andrea A., Begley, Thomas J., Sobol, Robert W., Hirschey, Matthew D., Ideker, Trey, Santos, Janine H., Copeland, William C., Tice, Raymond R., Balshaw, David M., Tyson, Frederick L.
Publicado 2014

Profiling of the Tox21 10K compound library for agonists and antagonists of the estrogen receptor alpha signaling pathway

por Huang, Ruili, Sakamuru, Srilatha, Martin, Matt T., Reif, David M., Judson, Richard S., Houck, Keith A., Casey, Warren, Hsieh, Jui-Hua, Shockley, Keith R., Ceger, Patricia, Fostel, Jennifer, Witt, Kristine L., Tong, Weida, Rotroff, Daniel M., Zhao, Tongan, Shinn, Paul, Simeonov, Anton, Dix, David J., Austin, Christopher P., Kavlock, Robert J., Tice, Raymond R., Xia, Menghang
Publicado 2014

Prediction of human population responses to toxic compounds by a collaborative competition

por Eduati, Federica, Mangravite, Lara M, Wang, Tao, Tang, Hao, Bare, J Christopher, Huang, Ruili, Norman, Thea, Kellen, Mike, Menden, Michael P, Yang, Jichen, Zhan, Xiaowei, Zhong, Rui, Xiao, Guanghua, Xia, Menghang, Abdo, Nour, Kosyk, Oksana, Friend, Stephen, Dearry, Allen, Simeonov, Anton, Tice, Raymond R, Rusyn, Ivan, Wright, Fred A, Stolovitzky, Gustavo, Xie, Yang, Saez-Rodriguez, Julio
Publicado 2015

DNA methylation in mice is influenced by genetics as well as sex and life experience

por Grimm, Sara A., Shimbo, Takashi, Takaku, Motoki, Thomas, James W., Auerbach, Scott, Bennett, Brian D., Bucher, John R., Burkholder, Adam B., Day, Frank, Du, Ying, Duncan, Christopher G., French, John E., Foley, Julie F., Li, Jianying, Merrick, B. Alex, Tice, Raymond R., Wang, Tianyuan, Xu, Xiaojiang, Bushel, Pierre R., Fargo, David C., Mullikin, James C., Wade, Paul A.
Publicado 2019

Comprehensive Analyses and Prioritization of Tox21 10K Chemicals Affecting Mitochondrial Function by in-Depth Mechanistic Studies

por Xia, Menghang, Huang, Ruili, Shi, Qiang, Boyd, Windy A., Zhao, Jinghua, Sun, Nuo, Rice, Julie R., Dunlap, Paul E., Hackstadt, Amber J., Bridge, Matt F., Smith, Marjolein V., Dai, Sheng, Zheng, Wei, Chu, Pei-Hsuan, Gerhold, David, Witt, Kristine L., DeVito, Michael, Freedman, Jonathan H., Austin, Christopher P., Houck, Keith A., Thomas, Russell S., Paules, Richard S., Tice, Raymond R., Simeonov, Anton
Publicado 2018