Enzyme - Switch sensors for therapeutic drug monitoring of immunotherapies

por Campbell, Emma, Adamson, Hope, Kohl, Declan, Tiede, Christian, Wälti, Christoph, Tomlinson, Darren C., Jeuken, Lars J.C.
Publicado 2023

Affimer proteins for F-actin: novel affinity reagents that label F-actin in live and fixed cells

por Lopata, Anna, Hughes, Ruth, Tiede, Christian, Heissler, Sarah M., Sellers, James R., Knight, Peter J., Tomlinson, Darren, Peckham, Michelle
Publicado 2018

Development of an Affimer-antibody combined immunological diagnosis kit for glypican-3

por Xie, Chunmei, Tiede, Christian, Zhang, Xuanyi, Wang, Congrong, Li, Zhixiong, Xu, Xiao, McPherson, Michael J., Tomlinson, Darren C., Xu, Weiwen
Publicado 2017

Ultraefficient Cap-Exchange Protocol To Compact Biofunctional Quantum Dots for Sensitive Ratiometric Biosensing and Cell Imaging

por Wang, Weili, Guo, Yuan, Tiede, Christian, Chen, Siyuan, Kopytynski, Michal, Kong, Yifei, Kulak, Alexander, Tomlinson, Darren, Chen, Rongjun, McPherson, Michael, Zhou, Dejian
Publicado 2017

Affimer reagents as tools in diagnosing plant virus diseases

por Hesketh, Emma L., Tiede, Christian, Adamson, Hope, Adams, Thomas L., Byrne, Matthew J., Meshcheriakova, Yulia, Kruse, Inga, McPherson, Michael J., Lomonossoff, George P., Tomlinson, Darren C., Ranson, Neil A.
Publicado 2019

Adhiron: a stable and versatile peptide display scaffold for molecular recognition applications

por Tiede, Christian, Tang, Anna A. S., Deacon, Sarah E., Mandal, Upasana, Nettleship, Joanne E., Owen, Robin L., George, Suja E., Harrison, David J., Owens, Raymond J., Tomlinson, Darren C., McPherson, Michael J.
Publicado 2014

Protein-conjugated microbubbles for the selective targeting of S. aureus biofilms

por Caudwell, Jack A., Tinkler, Jordan M., Johnson, Ben R.G., McDowall, Kenneth J., Alsulaimani, Fayez, Tiede, Christian, Tomlinson, Darren C., Freear, Steven, Turnbull, W. Bruce, Evans, Stephen D., Sandoe, Jonathan A.T.
Publicado 2022

Fibrinogen interaction with complement C3: a potential therapeutic target to reduce thrombosis risk

por King, Rhodri J., Schuett, Katharina, Tiede, Christian, Jankowski, Vera, John, Vicky, Trehan, Abhi, Simmons, Katie, Ponnambalam, Sreenivasan, Storey, Robert F., Fishwick, Colin W.G., McPherson, Michael J., Tomlinson, Darren C., Ajjan, Ramzi A.
Publicado 2020

Trivalent Gd-DOTA reagents for modification of proteins

por Fisher, Martin J., Williamson, Daniel J., Burslem, George M., Plante, Jeffrey P., Manfield, Iain W., Tiede, Christian, Ault, James R., Stockley, Peter G., Plein, Sven, Maqbool, Azhar, Tomlinson, Darren C., Foster, Richard, Warriner, Stuart L., Bon, Robin S.
Publicado 2015

Characterization and applications of a Crimean-Congo hemorrhagic fever virus nucleoprotein-specific Affimer: Inhibitory effects in viral replication and development of colorimetric...

por Álvarez-Rodríguez, Beatriz, Tiede, Christian, Hoste, Alexis C. R., Surtees, Rebecca A., Trinh, Chi H., Slack, Gillian S., Chamberlain, John, Hewson, Roger, Fresco, Alba, Sastre, Patricia, Tomlinson, Darren C., Millner, Paul A., Edwards, Thomas A., Barr, John N.
Publicado 2020

Nanoscale Pattern Extraction from Relative Positions of Sparse 3D Localizations

por Curd, Alistair P., Leng, Joanna, Hughes, Ruth E., Cleasby, Alexa J., Rogers, Brendan, Trinh, Chi H., Baird, Michelle A., Takagi, Yasuharu, Tiede, Christian, Sieben, Christian, Manley, Suliana, Schlichthaerle, Thomas, Jungmann, Ralf, Ries, Jonas, Shroff, Hari, Peckham, Michelle
Publicado 2020

“Affimer” synthetic protein scaffolds block oxidized LDL binding to the LOX-1 scavenger receptor and inhibit ERK1/2 activation

por Roper, Barnaby W.R., Tiede, Christian, Abdul-Zani, Izma, Cuthbert, Gary A., Jade, Dhananjay, Al-Aufi, Ahmed, Critchley, William R., Saikia, Queen, Homer-Vanniasinkam, Shervanthi, Sawamura, Tatsuya, McPherson, Michael J., Harrison, Michael A., Tomlinson, Darren C., Ponnambalam, Sreenivasan
Publicado 2023

Selective Affimers Recognise the BCL‐2 Family Proteins BCL‐x(L) and MCL‐1 through Noncanonical Structural Motifs

por Miles, Jennifer A., Hobor, Fruzsina, Trinh, Chi H., Taylor, James, Tiede, Christian, Rowell, Philip R., Jackson, Brian R., Nadat, Fatima A., Ramsahye, Pallavi, Kyle, Hannah F., Wicky, Basile I. M., Clarke, Jane, Tomlinson, Darren C., Wilson, Andrew J., Edwards, Thomas A.
Publicado 2020

RAS-inhibiting biologics identify and probe druggable pockets including an SII-α3 allosteric site

por Haza, Katarzyna Z., Martin, Heather L., Rao, Ajinkya, Turner, Amy L., Saunders, Sophie E., Petersen, Britta, Tiede, Christian, Tipping, Kevin, Tang, Anna A., Ajayi, Modupe, Taylor, Thomas, Harvey, Maia, Fishwick, Keri M., Adams, Thomas L., Gaule, Thembaninkosi G., Trinh, Chi H., Johnson, Matthew, Breeze, Alexander L., Edwards, Thomas A., McPherson, Michael J., Tomlinson, Darren C.
Publicado 2021

Affimer proteins are versatile and renewable affinity reagents

por Tiede, Christian, Bedford, Robert, Heseltine, Sophie J, Smith, Gina, Wijetunga, Imeshi, Ross, Rebecca, AlQallaf, Danah, Roberts, Ashley PE, Balls, Alexander, Curd, Alistair, Hughes, Ruth E, Martin, Heather, Needham, Sarah R, Zanetti-Domingues, Laura C, Sadigh, Yashar, Peacock, Thomas P, Tang, Anna A, Gibson, Naomi, Kyle, Hannah, Platt, Geoffrey W, Ingram, Nicola, Taylor, Thomas, Coletta, Louise P, Manfield, Iain, Knowles, Margaret, Bell, Sandra, Esteves, Filomena, Maqbool, Azhar, Prasad, Raj K, Drinkhill, Mark, Bon, Robin S, Patel, Vikesh, Goodchild, Sarah A, Martin-Fernandez, Marisa, Owens, Ray J, Nettleship, Joanne E, Webb, Michael E, Harrison, Michael, Lippiat, Jonathan D, Ponnambalam, Sreenivasan, Peckham, Michelle, Smith, Alastair, Ferrigno, Paul Ko, Johnson, Matt, McPherson, Michael J, Tomlinson, Darren Charles
Publicado 2017