Pharmacokinetic Modeling and Dose Selection in a Randomized, Double-Blind, Placebo-Controlled Trial of a Human Recombinant Alkaline Phosphatase in Healthy Volunteers

por Peters, Esther, Heuberger, Jules A. A. C., Tiessen, Renger, van Elsas, Andrea, Masereeuw, Rosalinde, Arend, Jacques, Stevens, Jasper, Pickkers, Peter
Publicado 2016

Safety, tolerability and pharmacodynamics of apical sodium-dependent bile acid transporter inhibition with volixibat in healthy adults and patients with type 2 diabetes mellitus: a...

por Tiessen, Renger G., Kennedy, Ciara A., Keller, Bradley T., Levin, Nancy, Acevedo, Lisette, Gedulin, Bronislava, van Vliet, Andre A., Dorenbaum, Alejandro, Palmer, Melissa
Publicado 2018

Similar Pharmacokinetics of the Adalimumab (Humira(®)) Biosimilar BI 695501 Whether Administered via Subcutaneous Autoinjector or Prefilled Syringe (VOLTAIRE(®)-AI and VOLTAIRE(®)-...

por Ramael, Steven, Van Hoorick, Benjamin, Tiessen, Renger, van Iersel, Thijs, Moschetti, Viktoria, Lang, Benjamin, Sonderegger, Ivo, Wiebe, Sabrina, Liedert, Bernd, Jayadeva, Girish
Publicado 2018

M281, an Anti‐FcRn Antibody: Pharmacodynamics, Pharmacokinetics, and Safety Across the Full Range of IgG Reduction in a First‐in‐Human Study

por Ling, Leona E., Hillson, Jan L., Tiessen, Renger G., Bosje, Tjerk, van Iersel, Mattheus Paulus, Nix, Darrell J., Markowitz, Lynn, Cilfone, Nicholas A., Duffner, Jay, Streisand, James B., Manning, Anthony M., Arroyo, Santiago
Publicado 2018