Aiming drug discovery at lysophosphatidic acid targets

por Tigyi, Gabor
Publicado 2010

A two-step approach to qPCR experimental design and software for data analysis

por Guo, Huazhang, Tague, Larry, Ray, Ramesh, Tigyi, Gabor
Publicado 2010

First International Conference on Lysophospholipids and Related Bioactive Lipids in Biology and Disease Sponsored by the Federation of American Societies of Experimental Biology

por Goetzl, Edward J., Tigyi, Gabor J., Hla, Timothy
Publicado 2001

Designing Dual Inhibitors of Autotaxin-LPAR GPCR Axis

por Banerjee, Souvik, Lee, Suechin, Norman, Derek D., Tigyi, Gabor J.
Publicado 2022

LPA(5) Is an Inhibitory Receptor That Suppresses CD8 T-Cell Cytotoxic Function via Disruption of Early TCR Signaling

por Mathew, Divij, Kremer, Kimberly N., Strauch, Pamela, Tigyi, Gabor, Pelanda, Roberta, Torres, Raul M.
Publicado 2019

Anti-cancer strategies targeting the autotaxin-lysophosphatidic acid receptor axis: is there a path forward?

por Tigyi, Gábor, Dacheux, Mélanie A., Lin, Kuan-Hung, Yue, Junming, Norman, Derek, Benyó, Zoltán, Lee, Sue Chin
Publicado 2021

EIF5A2 controls ovarian tumor growth and metastasis by promoting epithelial to mesenchymal transition via the TGFβ pathway

por Zhao, Guannan, Zhang, Wenjing, Dong, Peixin, Watari, Hidemichi, Guo, Yuqi, Pfeffer, Lawrence M., Tigyi, Gabor, Yue, Junming
Publicado 2021

Adipose-Derived Stem Cells Facilitate Ovarian Tumor Growth and Metastasis by Promoting Epithelial to Mesenchymal Transition Through Activating the TGF-β Pathway

por Liu, Xiaowu, Zhao, Guannan, Huo, Xueyun, Wang, Yaohong, Tigyi, Gabor, Zhu, Bing-Mei, Yue, Junming, Zhang, Wenjing
Publicado 2021

Opposing Roles of S1P(3) Receptors in Myocardial Function

por Wafa, Dina, Koch, Nóra, Kovács, Janka, Kerék, Margit, Proia, Richard L., Tigyi, Gábor J., Benyó, Zoltán, Miklós, Zsuzsanna
Publicado 2020

Enhancement of Sphingomyelinase-Induced Endothelial Nitric Oxide Synthase-Mediated Vasorelaxation in a Murine Model of Type 2 Diabetes

por Ruisanchez, Éva, Janovicz, Anna, Panta, Rita Cecília, Kiss, Levente, Párkányi, Adrienn, Straky, Zsuzsa, Korda, Dávid, Liliom, Károly, Tigyi, Gábor, Benyó, Zoltán
Publicado 2023

FTY720 and (S)-FTY720 vinylphosphonate inhibit sphingosine kinase 1 and promote its proteasomal degradation in human pulmonary artery smooth muscle, breast cancer and androgen-inde...

por Tonelli, Francesca, Lim, Keng Gat, Loveridge, Carolyn, Long, Jaclyn, Pitson, Stuart M., Tigyi, Gabor, Bittman, Robert, Pyne, Susan, Pyne, Nigel J.
Publicado 2010

Regulation of Tumor Immunity by Lysophosphatidic Acid

por Lee, Sue Chin, Dacheux, Mélanie A., Norman, Derek D., Balázs, Louisa, Torres, Raul M., Augelli-Szafran, Corinne E., Tigyi, Gábor J.
Publicado 2020

Prometastatic Effect of ATX Derived from Alveolar Type II Pneumocytes and B16-F10 Melanoma Cells

por Dacheux, Mélanie A., Lee, Sue Chin, Shin, Yoojin, Norman, Derek D., Lin, Kuan-Hung, E, Shuyu, Yue, Junming, Benyó, Zoltán, Tigyi, Gábor J.
Publicado 2022

Lysophosphatidic acid induces proliferation and osteogenic differentiation of human dental pulp stem cell through lysophosphatidic acid receptor 3/extracellular signal-regulated ki...

por Heo, Soon Chul, Keum, Bo Ram, Seo, Eun Jin, Yoon, Jinhwan, Jeong, Sanghwa, Tigyi, Gabor J., Norman, Derek, Jang, Il Ho, Kim, Hyung Joon
Publicado 2023

A Luminacin D Analog HL142 Inhibits Ovarian Tumor Growth and Metastasis by Reversing EMT and Attenuating the TGFβ and FAK Pathways

por Wang, Baojin, Li, Hanxuan, Zhao, Xinxin, Zhang, Wenjing, Zhao, Guannan, Wu, Zhongzhi, Zhang, Ruitao, Dong, Peixin, Watari, Hidemichi, Tigyi, Gabor, Li, Wei, Yue, Junming
Publicado 2021

Design and Synthesis of Sulfamoyl Benzoic Acid Analogues with Subnanomolar Agonist Activity Specific to the LPA(2) Receptor

por Patil, Renukadevi, Fells, James I., Szabó, Erzsébet, Lim, Keng G., Norman, Derek D., Balogh, Andrea, Patil, Shivaputra, Strobos, Jur, Miller, Duane D., Tigyi, Gábor J.
Publicado 2014

Sphingosine-1-Phosphate Enhances α(1)-Adrenergic Vasoconstriction via S1P2–G(12/13)–ROCK Mediated Signaling

por Panta, Cecília R., Ruisanchez, Éva, Móré, Dorottya, Dancs, Péter T., Balogh, Andrea, Fülöp, Ágnes, Kerék, Margit, Proia, Richard L., Offermanns, Stefan, Tigyi, Gábor J., Benyó, Zoltán
Publicado 2019

Cryptotanshinone inhibits ovarian tumor growth and metastasis by degrading c-Myc and attenuating the FAK signaling pathway

por Guo, Huijun, Zhang, Wenjing, Wang, Jiaxing, Zhao, Guannan, Wang, Yaohong, Zhu, Bing-Mei, Dong, Peixin, Watari, Hidemichi, Wang, Baojin, Li, Wei, Tigyi, Gabor, Yue, Junming
Publicado 2022

Doxycycline Inducible Kruppel-Like Factor 4 Lentiviral Vector Mediates Mesenchymal to Epithelial Transition in Ovarian Cancer Cells

por Chen, Zixuan, Wang, Yinan, Liu, Wen, Zhao, Guannan, Lee, Suechin, Balogh, Andrea, Zou, Yanan, Guo, Yuqi, Zhang, Zhan, Gu, Weiwang, Li, Chengyao, Tigyi, Gabor, Yue, Junming
Publicado 2014

Paneth cell dysfunction in radiation injury and radio-mitigation by human α-defensin 5

por Shukla, Pradeep K., Rao, Roshan G., Meena, Avtar S., Giorgianni, Francesco, Lee, Sue Chin, Raju, Preeti, Shashikanth, Nitesh, Shekhar, Chandra, Beranova, Sarka, Balazs, Louisa, Tigyi, Gabor, Gosain, Ankush, Rao, RadhaKrishna
Publicado 2023