Mechanism of sodium channel block by local anesthetics, antiarrhythmics, and anticonvulsants

por Tikhonov, Denis B., Zhorov, Boris S.
Publicado 2017

Predicting Structural Details of the Sodium Channel Pore Basing on Animal Toxin Studies

por Tikhonov, Denis B., Zhorov, Boris S.
Publicado 2018

Computational Analysis of the Crystal and Cryo-EM Structures of P-Loop Channels with Drugs

por Tikhonov, Denis B., Zhorov, Boris S.
Publicado 2021

P-Loop Channels: Experimental Structures, and Physics-Based and Neural Networks-Based Models

por Tikhonov, Denis B., Zhorov, Boris S.
Publicado 2022

Folding similarity of the outer pore region in prokaryotic and eukaryotic sodium channels revealed by docking of conotoxins GIIIA, PIIIA, and KIIIA in a NavAb-based model of Nav1.4

por Korkosh, Viacheslav S., Zhorov, Boris S., Tikhonov, Denis B.
Publicado 2014

Possible Compensatory Role of ASICs in Glutamatergic Synapses

por Evlanenkov, Konstantin K., Zhigulin, Arseniy S., Tikhonov, Denis B.
Publicado 2023

Hydrophobic Amines and Their Guanidine Analogues Modulate Activation and Desensitization of ASIC3

por Shteinikov, Vasilii Y, Potapieva, Natalia N, Gmiro, Valery E, Tikhonov, Denis B
Publicado 2019

Probing the Proton-Gated ASIC Channels Using Tetraalkylammonium Ions

por Evlanenkov, Konstantin K., Nikolaev, Maxim V., Potapieva, Natalia N., Bolshakov, Konstantin V., Tikhonov, Denis B.
Publicado 2023

Derivatives of 2-aminobenzimidazole potentiate ASIC open state with slow kinetics of activation and desensitization

por Evlanenkov, Konstantin K, Komarova, Margarita S, Dron, Mikhail Y, Nikolaev, Maxim V, Zhukovskaya, Olga N, Gurova, Nataliya A, Tikhonov, Denis B
Publicado 2023

Batrachotoxin acts as a stent to hold open homotetrameric prokaryotic voltage-gated sodium channels

por Finol-Urdaneta, Rocio K., McArthur, Jeffrey R., Goldschen-Ohm, Marcel P., Gaudet, Rachelle, Tikhonov, Denis B., Zhorov, Boris S., French, Robert J.
Publicado 2019

Extremely Potent Block of Bacterial Voltage-Gated Sodium Channels by µ-Conotoxin PIIIA

por Finol-Urdaneta, Rocio K., McArthur, Jeffrey R., Korkosh, Vyacheslav S., Huang, Sun, McMaster, Denis, Glavica, Robert, Tikhonov, Denis B., Zhorov, Boris S., French, Robert J.
Publicado 2019

TRPV1 activation power can switch an action mode for its polypeptide ligands

por Nikolaev, Maxim V., Dorofeeva, Natalia A., Komarova, Margarita S., Korolkova, Yuliya V., Andreev, Yaroslav A., Mosharova, Irina V., Grishin, Eugene V., Tikhonov, Denis B., Kozlov, Sergey A.
Publicado 2017

ω-Tbo-IT1–New Inhibitor of Insect Calcium Channels Isolated from Spider Venom

por Mikov, Alexander N., Fedorova, Irina M., Potapieva, Natalia N., Maleeva, Ekaterina E., Andreev, Yaroslav A., Zaitsev, Alexey V., Kim, Kira K., Bocharov, Eduard V., Bozin, Timur N., Altukhov, Dmitry A., Lipkin, Alexey V., Kozlov, Sergey A., Tikhonov, Denis B., Grishin, Eugene V.
Publicado 2015