Mouse Models of Cardiomyopathies Caused by Mutations in Troponin C

por Tikunova, Svetlana B., Thuma, Jenna, Davis, Jonathan P.
Publicado 2023

Measurement of Calcium Dissociation Rates from Troponin C in Rigor Skeletal Myofibrils

por Little, Sean C., Tikunova, Svetlana B., Norman, Catalina, Swartz, Darl R., Davis, Jonathan P.
Publicado 2011

Disease-Related Cardiac Troponins Alter Thin Filament Ca(2+) Association and Dissociation Rates

por Liu, Bin, Tikunova, Svetlana B., Kline, Kristopher P., Siddiqui, Jalal K., Davis, Jonathan P.
Publicado 2012

Targeting Troponin C with Small Molecules Containing Diphenyl Moieties: Calcium Sensitivity Effects on Striated Muscle and Structure Activity Relationship

por Hantz, Eric R., Tikunova, Svetlana B., Belevych, Natalya, Davis, Jonathan P., Reiser, Peter J., Lindert, Steffen
Publicado 2023

Knock-in mice harboring a Ca(2+) desensitizing mutation in cardiac troponin C develop early onset dilated cardiomyopathy

por McConnell, Bradley K., Singh, Sonal, Fan, Qiying, Hernandez, Adriana, Portillo, Jesus P., Reiser, Peter J., Tikunova, Svetlana B.
Publicado 2015

Divergent Soybean Calmodulins Respond Similarly to Calcium Transients: Insight into Differential Target Regulation

por Walton, Shane D., Chakravarthy, Harshini, Shettigar, Vikram, O’Neil, Andrew J., Siddiqui, Jalal K., Jones, Benjamin R., Tikunova, Svetlana B., Davis, Jonathan P.
Publicado 2017

3-Chlorodiphenylamine activates cardiac troponin by a mechanism distinct from bepridil or TFP

por Tikunova, Svetlana B., Cuesta, Andres, Price, Morgan, Li, Monica X., Belevych, Natalya, Biesiadecki, Brandon J., Reiser, Peter J., Hwang, Peter M., Davis, Jonathan P.
Publicado 2019

Photorhabdus luminescens TccC3 Toxin Targets the Dynamic Population of F-Actin and Impairs Cell Cortex Integrity

por Dong, Songyu, Zheng, Weili, Pinkerton, Nicholas, Hansen, Jacob, Tikunova, Svetlana B., Davis, Jonathan P., Heissler, Sarah M., Kudryashova, Elena, Egelman, Edward H., Kudryashov, Dmitri S.
Publicado 2022

Gene Transfer of Engineered Calmodulin Alleviates Ventricular Arrhythmias in a Calsequestrin‐Associated Mouse Model of Catecholaminergic Polymorphic Ventricular Tachycardia

por Liu, Bin, Walton, Shane D., Ho, Hsiang‐Ting, Belevych, Andriy E., Tikunova, Svetlana B., Bonilla, Ingrid, Shettigar, Vikram, Knollmann, Bjorn C., Priori, Silvia G., Volpe, Pompeo, Radwański, Przemysław B., Davis, Jonathan P., Györke, Sándor
Publicado 2018

Small Molecule RPI-194 Stabilizes Activated Troponin to Increase the Calcium Sensitivity of Striated Muscle Contraction

por Mahmud, Zabed, Tikunova, Svetlana, Belevych, Natalya, Wagg, Cory S., Zhabyeyev, Pavel, Liu, Philip B., Rasicci, David V., Yengo, Christopher M., Oudit, Gavin Y., Lopaschuk, Gary D., Reiser, Peter J., Davis, Jonathan P., Hwang, Peter M.
Publicado 2022

Myofilament Calcium Sensitivity: Consequences of the Effective Concentration of Troponin I

por Siddiqui, Jalal K., Tikunova, Svetlana B., Walton, Shane D., Liu, Bin, Meyer, Meredith, de Tombe, Pieter P., Neilson, Nathan, Kekenes-Huskey, Peter M., Salhi, Hussam E., Janssen, Paul M. L., Biesiadecki, Brandon J., Davis, Jonathan P.
Publicado 2016