Effective modulation of stromal signaling through ROCK inhibition: Is it all in the timing?

por Chin, Venessa T., Vennin, Claire, Timpson, Paul, Pajic, Marina
Publicado 2017

Targeting the complexity of Src signalling in the tumour microenvironment of pancreatic cancer: from mechanism to therapy

por Parkin, Ashleigh, Man, Jennifer, Timpson, Paul, Pajic, Marina
Publicado 2019

Intravital imaging reveals new ancillary mechanisms co-opted by cancer cells to drive tumor progression

por Vennin, Claire, Herrmann, David, Lucas, Morghan C., Timpson, Paul
Publicado 2016

Transient targeting of the pancreatic cancer stroma as a ‘fine-tuned’ anti-tumor and anti-metastatic therapy

por Vennin, Claire, Cox, Thomas R., Pajic, Marina, Timpson, Paul
Publicado 2017

Mtss1 regulates epidermal growth factor signaling in head and neck squamous carcinoma cells

por Dawson, John C., Timpson, Paul, Kalna, Gabriela, Machesky, Laura M.
Publicado 2011

The cancer cell secretome drives cooperative manipulation of the tumour microenvironment to accelerate tumourigenesis

por Ritchie, Shona, Reed, Daniel A, Pereira, Brooke A, Timpson, Paul
Publicado 2021

Overcoming the senescence‐associated secretory phenotype (SASP): a complex mechanism of resistance in the treatment of cancer

por Chambers, Cecilia R., Ritchie, Shona, Pereira, Brooke A., Timpson, Paul
Publicado 2021

There are four dynamically and functionally distinct populations of E-cadherin in cell junctions

por Erami, Zahra, Timpson, Paul, Yao, Wu, Zaidel-Bar, Ronen, Anderson, Kurt I.
Publicado 2015

Acute compressive stress activates RHO/ROCK-mediated cellular processes

por Boyle, Sarah T., Kular, Jasreen, Nobis, Max, Ruszkiewicz, Andrew, Timpson, Paul, Samuel, Michael S.
Publicado 2018

Combating pancreatic cancer with PI3K pathway inhibitors in the era of personalised medicine

por Conway, James RW, Herrmann, David, Evans, TR Jeffry, Morton, Jennifer P, Timpson, Paul
Publicado 2019

Dynamic Stromal Alterations Influence Tumor-Stroma Crosstalk to Promote Pancreatic Cancer and Treatment Resistance

por Murphy, Kendelle J., Chambers, Cecilia R., Herrmann, David, Timpson, Paul, Pereira, Brooke A.
Publicado 2021

A role for the actin cytoskeleton in cell death and aging in yeast

por Gourlay, Campbell W., Carpp, Lindsay N., Timpson, Paul, Winder, Steven J., Ayscough, Kathryn R.
Publicado 2004

Myeloid cell leukemia 1 (MCL-1), an unexpected modulator of protein kinase signaling during invasion

por Young, Adelaide IJ, Timpson, Paul, Gallego-Ortega, David, Ormandy, Christopher J., Oakes, Samantha R.
Publicado 2017

Morphogenesis of extra-embryonic tissues directs the remodelling of the mouse embryo at implantation

por Christodoulou, Neophytos, Weberling, Antonia, Strathdee, Douglas, Anderson, Kurt I., Timpson, Paul, Zernicka-Goetz, Magdalena
Publicado 2019

Focal adhesion kinase priming in pancreatic cancer, altering biomechanics to improve chemotherapy

por Murphy, Kendelle J., Zhu, Jessie, Trpceski, Michael, Pereira, Brooke A., Timpson, Paul, Herrmann, David
Publicado 2022

Inhibition of autophagy impairs tumor cell invasion in an organotypic model

por Macintosh, Robin L., Timpson, Paul, Thorburn, Jacqueline, Anderson, Kurt I., Thorburn, Andrew, Ryan, Kevin M.
Publicado 2012

Differential Rac1 signalling by guanine nucleotide exchange factors implicates FLII in regulating Rac1-driven cell migration

por Marei, Hadir, Carpy, Alejandro, Woroniuk, Anna, Vennin, Claire, White, Gavin, Timpson, Paul, Macek, Boris, Malliri, Angeliki
Publicado 2016

Recent advances in understanding the complexities of metastasis

por Chitty, Jessica L., Filipe, Elysse C., Lucas, Morghan C., Herrmann, David, Cox, Thomas R., Timpson, Paul
Publicado 2018

Organotypic Collagen I Assay: A Malleable Platform to Assess Cell Behaviour in a 3-Dimensional Context

por Timpson, Paul, Mcghee, Ewan J., Erami, Zahra, Nobis, Max, Quinn, Jean A., Edward, Mike, Anderson, Kurt I.
Publicado 2011

Rho-associated kinase signalling and the cancer microenvironment: novel biological implications and therapeutic opportunities

por Chin, Venessa T., Nagrial, Adnan M., Chou, Angela, Biankin, Andrew V., Gill, Anthony J., Timpson, Paul, Pajic, Marina
Publicado 2015