Pancreatic Ductal Adenocarcinoma Induces Neural Injury that Promotes a Transcriptomic and Functional Repair Signature by Peripheral Neuroglia

por Weitz, Jonathan, Garg, Bharti, Tiriac, Herve, Martsinkovskiy, Alexei, Patel, Sandip, Lowy, Andrew
Publicado 2023

Using Organotypic Tissue Slices to Investigate the Microenvironment of Pancreatic Cancer: Pharmacotyping and Beyond

por Weitz, Jonathan Robert, Tiriac, Herve, Hurtado de Mendoza, Tatiana, Wascher, Alexis, Lowy, Andrew M.
Publicado 2021

Advanced Development of Primary Pancreatic Organoid Tumor Models for High-Throughput Phenotypic Drug Screening

por Hou, Shurong, Tiriac, Hervé, Sridharan, Banu Priya, Scampavia, Louis, Madoux, Franck, Seldin, Jan, Souza, Glauco R., Watson, Donald, Tuveson, David, Spicer, Timothy P.
Publicado 2018

TP63-Mediated Enhancer Reprogramming Drives the Squamous Subtype of Pancreatic Ductal Adenocarcinoma

por Somerville, Tim D.D., Xu, Yali, Miyabayashi, Koji, Tiriac, Hervé, Cleary, Cristian R., Maia-Silva, Diogo, Milazzo, Joseph P., Tuveson, David A., Vakoc, Christopher R.
Publicado 2018

Treatment of pancreatic cancer with irreversible electroporation and intratumoral CD40 antibody stimulates systemic immune responses that inhibit liver metastasis in an orthotopic...

por Shankara Narayanan, Jayanth S, Hayashi, Tomoko, Erdem, Suna, McArdle, Sara, Tiriac, Herve, Ray, Partha, Pu, Minya, Mikulski, Zbigniew, Miller, Aaron, Messer, Karen, Carson, Dennis, Schoenberger, Stephen, White, Rebekah R
Publicado 2023

CDPKs CPK6 and CPK3 Function in ABA Regulation of Guard Cell S-Type Anion- and Ca(2+)- Permeable Channels and Stomatal Closure

por Mori, Izumi C, Murata, Yoshiyuki, Yang, Yingzhen, Munemasa, Shintaro, Wang, Yong-Fei, Andreoli, Shannon, Tiriac, Hervé, Alonso, Jose M, Harper, Jeffery F, Ecker, Joseph R, Kwak, June M, Schroeder, Julian I
Publicado 2006

Dual Inhibition of KRAS(G12D) and Pan-ERBB Is Synergistic in Pancreatic Ductal Adenocarcinoma

por Gulay, Kevin Christian Montecillo, Zhang, Xinlian, Pantazopoulou, Vasiliki, Patel, Jay, Esparza, Edgar, Pran Babu, Deepa Sheik, Ogawa, Satoshi, Weitz, Jonathan, Ng, Isabella, Mose, Evangeline S., Pu, Minya, Engle, Dannielle D., Lowy, Andrew M., Tiriac, Hervé
Publicado 2023

Conjugation to the sigma-2 ligand SV119 overcomes uptake blockade and converts dm-Erastin into a potent pancreatic cancer therapeutic

por Ohman, Kerri A., Hashim, Yassar M., Vangveravong, Suwanna, Nywening, Timothy M., Cullinan, Darren R., Goedegebuure, S. Peter, Liu, Jingxia, Van Tine, Brian A., Tiriac, Herve, Tuveson, David A., DeNardo, David G., Spitzer, Dirk, Mach, Robert H., Hawkins, William G.
Publicado 2016

Distinct populations of inflammatory fibroblasts and myofibroblasts in pancreatic cancer

por Öhlund, Daniel, Handly-Santana, Abram, Biffi, Giulia, Elyada, Ela, Almeida, Ana S., Ponz-Sarvise, Mariano, Corbo, Vincenzo, Oni, Tobiloba E., Hearn, Stephen A., Lee, Eun Jung, Chio, Iok In Christine, Hwang, Chang-Il, Tiriac, Hervé, Baker, Lindsey A., Engle, Dannielle D., Feig, Christine, Kultti, Anne, Egeblad, Mikala, Fearon, Douglas T., Crawford, James M., Clevers, Hans, Park, Youngkyu, Tuveson, David A.
Publicado 2017

Dynamic changes during the treatment of pancreatic cancer

por Wolff, Robert A., Wang-Gillam, Andrea, Alvarez, Hector, Tiriac, Hervé, Engle, Dannielle, Hou, Shurong, Groff, Abigail F., San Lucas, Anthony, Bernard, Vincent, Allenson, Kelvin, Castillo, Jonathan, Kim, Dong, Mulu, Feven, Huang, Jonathan, Stephens, Bret, Wistuba, Ignacio I., Katz, Matthew, Varadhachary, Gauri, Park, YoungKyu, Hicks, James, Chinnaiyan, Arul, Scampavia, Louis, Spicer, Timothy, Gerhardinger, Chiara, Maitra, Anirban, Tuveson, David, Rinn, John, Lizee, Gregory, Yee, Cassian, Levine, Arnold J.
Publicado 2018

Vestigial-like 1 is a shared targetable cancer-placenta antigen expressed by pancreatic and basal-like breast cancers

por Bradley, Sherille D., Talukder, Amjad H., Lai, Ivy, Davis, Rebecca, Alvarez, Hector, Tiriac, Herve, Zhang, Minying, Chiu, Yulun, Melendez, Brenda, Jackson, Kyle R., Katailiha, Arjun, Sonnemann, Heather M., Li, Fenge, Kang, Yaan, Qiao, Na, Pan, Bih-Fang, Lorenzi, Philip L., Hurd, Mark, Mittendorf, Elizabeth A., Peterson, Christine B., Javle, Milind, Bristow, Christopher, Kim, Michael, Tuveson, David A., Hawke, David, Kopetz, Scott, Wolff, Robert A., Hwu, Patrick, Maitra, Anirban, Roszik, Jason, Yee, Cassian, Lizée, Gregory
Publicado 2020

A super-enhancer-regulated RNA-binding protein cascade drives pancreatic cancer

por Antal, Corina E., Oh, Tae Gyu, Aigner, Stefan, Luo, En-Ching, Yee, Brian A., Campos, Tania, Tiriac, Hervé, Rothamel, Katherine L., Cheng, Zhang, Jiao, Henry, Wang, Allen, Hah, Nasun, Lenkiewicz, Elizabeth, Lumibao, Jan C., Truitt, Morgan L., Estepa, Gabriela, Banayo, Ester, Bashi, Senada, Esparza, Edgar, Munoz, Ruben M., Diedrich, Jolene K., Sodir, Nicole M., Mueller, Jasmine R., Fraser, Cory R., Borazanci, Erkut, Propper, David, Von Hoff, Daniel D., Liddle, Christopher, Yu, Ruth T., Atkins, Annette R., Han, Haiyong, Lowy, Andrew M., Barrett, Michael T., Engle, Dannielle D., Evan, Gerard I., Yeo, Gene W., Downes, Michael, Evans, Ronald M.
Publicado 2023