Dynamic Properties of the DNA Damage Response Mre11/Rad50 Complex

por Vertemara, Jacopo, Tisi, Renata
Publicado 2023

Molecular Dynamics Simulations Reveal Structural Interconnections within Sec14-PH Bipartite Domain from Human Neurofibromin

por Rizza, Fabio, Vertemara, Jacopo, Tisi, Renata
Publicado 2022

Natural Products Attenuating Biosynthesis, Processing, and Activity of Ras Oncoproteins: State of the Art and Future Perspectives

por Tisi, Renata, Gaponenko, Vadim, Vanoni, Marco, Sacco, Elena
Publicado 2020

Functional and structural insights into the MRX/MRN complex, a key player in recognition and repair of DNA double-strand breaks

por Tisi, Renata, Vertemara, Jacopo, Zampella, Giuseppe, Longhese, Maria Pia
Publicado 2020

AMPK Phosphorylation Is Controlled by Glucose Transport Rate in a PKA-Independent Manner

por Milanesi, Riccardo, Tripodi, Farida, Vertemara, Jacopo, Tisi, Renata, Coccetti, Paola
Publicado 2021

Modeling Calcium Signaling in S. cerevisiae Highlights the Role and Regulation of the Calmodulin-Calcineurin Pathway in Response to Hypotonic Shock

por Spolaor, Simone, Rovetta, Mattia, Nobile, Marco S., Cazzaniga, Paolo, Tisi, Renata, Besozzi, Daniela
Publicado 2022

Cannabidiol Antiproliferative Effect in Triple-Negative Breast Cancer MDA-MB-231 Cells Is Modulated by Its Physical State and by IGF-1

por D’Aloia, Alessia, Ceriani, Michela, Tisi, Renata, Stucchi, Simone, Sacco, Elena, Costa, Barbara
Publicado 2022

The Ku complex promotes DNA end-bridging and this function is antagonized by Tel1/ATM kinase

por Rinaldi, Carlo, Pizzul, Paolo, Casari, Erika, Mangiagalli, Marco, Tisi, Renata, Longhese, Maria Pia
Publicado 2023

The ATP-bound conformation of the Mre11–Rad50 complex is essential for Tel1/ATM activation

por Cassani, Corinne, Vertemara, Jacopo, Bassani, Matteo, Marsella, Antonio, Tisi, Renata, Zampella, Giuseppe, Longhese, Maria Pia
Publicado 2019

The Ycx1 protein encoded by the yeast YDL206W gene plays a role in calcium and calcineurin signaling

por Lee, Grace M., Weng, Fangli, Cranley, Juliana, Rajasekhar, Abhinav, Stoeckel, Matthew, Kane, Thomas, Tisi, Renata, Wang, Yuqi
Publicado 2023

DNA binding modes influence Rap1 activity in the regulation of telomere length and MRX functions at DNA ends

por Bonetti, Diego, Rinaldi, Carlo, Vertemara, Jacopo, Notaro, Marco, Pizzul, Paolo, Tisi, Renata, Zampella, Giuseppe, Longhese, Maria Pia
Publicado 2020

Sae2 and Rif2 regulate MRX endonuclease activity at DNA double-strand breaks in opposite manners

por Marsella, Antonio, Gobbini, Elisa, Cassani, Corinne, Tisi, Renata, Cannavo, Elda, Reginato, Giordano, Cejka, Petr, Longhese, Maria Pia
Publicado 2021

Structurally distinct Mre11 domains mediate MRX functions in resection, end-tethering and DNA damage resistance

por Cassani, Corinne, Gobbini, Elisa, Vertemara, Jacopo, Wang, Weibin, Marsella, Antonio, Sung, Patrick, Tisi, Renata, Zampella, Giuseppe, Longhese, Maria Pia
Publicado 2018

Synthesis, Molecular Modeling and Biological Evaluation of Metabolically Stable Analogues of the Endogenous Fatty Acid Amide Palmitoylethanolamide

por D’Aloia, Alessia, Arrigoni, Federica, Tisi, Renata, Palmioli, Alessandro, Ceriani, Michela, Artusa, Valentina, Airoldi, Cristina, Zampella, Giuseppe, Costa, Barbara, Cipolla, Laura
Publicado 2020

Novel pathological variants of NHP2 affect N-terminal domain flexibility, protein stability, H/ACA Ribonucleoprotein (RNP) complex formation and telomerase activity

por Maliński, Bartosz, Vertemara, Jacopo, Faustini, Elena, Ladenvall, Claes, Norberg, Anna, Zhang, Yuming, von Castelmur, Eleonore, Baliakas, Panagiotis, Tisi, Renata, Cammenga, Jörg, Lottersberger, Francisca
Publicado 2023

The Multi-Level Mechanism of Action of a Pan-Ras Inhibitor Explains its Antiproliferative Activity on Cetuximab-Resistant Cancer Cells

por Tisi, Renata, Spinelli, Michela, Palmioli, Alessandro, Airoldi, Cristina, Cazzaniga, Paolo, Besozzi, Daniela, Nobile, Marco S., Mazzoleni, Elisa, Arnhold, Simone, De Gioia, Luca, Grandori, Rita, Peri, Francesco, Vanoni, Marco, Sacco, Elena
Publicado 2021