G-protein-coupled receptor structure: what can we learn?

por Tobin, Andrew B
Publicado 2009

Crosstalk between the M(1) muscarinic acetylcholine receptor and the endocannabinoid system: A relevance for Alzheimer's disease?

por Thompson, Karen J., Tobin, Andrew B.
Publicado 2020

Targeting the M1 muscarinic acetylcholine receptor in Alzheimer’s disease

por Dwomoh, Louis, Tejeda, Gonzalo S., Tobin, Andrew B.
Publicado 2022

How Arrestins and GRKs Regulate the Function of Long Chain Fatty Acid Receptors

por Alharbi, Abdulrahman G., Tobin, Andrew B., Milligan, Graeme
Publicado 2022

Location, location, location…site-specific GPCR phosphorylation offers a mechanism for cell-type-specific signalling

por Tobin, Andrew B., Butcher, Adrian J., Kong, Kok Choi
Publicado 2008

Employing novel animal models in the design of clinically efficacious GPCR ligands()

por Bradley, Sophie J, Riaz, Sajjad A, Tobin, Andrew B
Publicado 2014

Regulation of p53 expression, phosphorylation and sub-cellular localisation by a G-protein coupled receptor

por Solyakov, Lev, Sayan, Emre, Riley, Joan, Pointon, Amy, Tobin, Andrew B
Publicado 2009

Therapeutic validation of an orphan G protein‐coupled receptor: The case of GPR84

por Marsango, Sara, Barki, Natasja, Jenkins, Laura, Tobin, Andrew B., Milligan, Graeme
Publicado 2020

Therapeutic Opportunities and Challenges in Targeting the Orphan G Protein-Coupled Receptor GPR35

por Quon, Tezz, Lin, Li-Chiung, Ganguly, Amlan, Tobin, Andrew B., Milligan, Graeme
Publicado 2020

FFA4/GPR120: Pharmacology and Therapeutic Opportunities

por Milligan, Graeme, Alvarez-Curto, Elisa, Hudson, Brian D., Prihandoko, Rudi, Tobin, Andrew B.
Publicado 2017

G Protein-Coupled Receptor GPR35 Suppresses Lipid Accumulation in Hepatocytes

por Lin, Li-Chiung, Quon, Tezz, Engberg, Susanna, Mackenzie, Amanda E., Tobin, Andrew B., Milligan, Graeme
Publicado 2021

ERK5 Activation by Gq-Coupled Muscarinic Receptors Is Independent of Receptor Internalization and β-Arrestin Recruitment

por Sánchez-Fernández, Guzmán, Cabezudo, Sofía, García-Hoz, Carlota, Tobin, Andrew B., Mayor Jr, Federico, Ribas, Catalina
Publicado 2013

A growing understanding of the role of muscarinic receptors in the molecular pathology and treatment of schizophrenia

por Dean, Brian, Bakker, Geor, Ueda, Hiroki R., Tobin, Andrew B., Brown, Alastair, Kanaan, Richard A. A.
Publicado 2023

Targeted Elimination of G Proteins and Arrestins Defines Their Specific Contributions to Both Intensity and Duration of G Protein-coupled Receptor Signaling

por Alvarez-Curto, Elisa, Inoue, Asuka, Jenkins, Laura, Raihan, Sheikh Zahir, Prihandoko, Rudi, Tobin, Andrew B., Milligan, Graeme
Publicado 2016

Phosphorylation and regulation of a G protein–coupled receptor by protein kinase CK2

por Torrecilla, Ignacio, Spragg, Elizabeth J., Poulin, Benoit, McWilliams, Phillip J., Mistry, Sharad C., Blaukat, Andree, Tobin, Andrew B.
Publicado 2007

N-Methyl-d-aspartate Receptors Mediate the Phosphorylation and Desensitization of Muscarinic Receptors in Cerebellar Granule Neurons

por Butcher, Adrian J., Torrecilla, Ignacio, Young, Kenneth W., Kong, Kok Choi, Mistry, Sharad C., Bottrill, Andrew R., Tobin, Andrew B.
Publicado 2009

Malaria Protein Kinase CK2 (PfCK2) Shows Novel Mechanisms of Regulation

por Graciotti, Michele, Alam, Mahmood, Solyakov, Lev, Schmid, Ralf, Burley, Glenn, Bottrill, Andrew R., Doerig, Christian, Cullis, Paul, Tobin, Andrew B.
Publicado 2014

Concomitant Action of Structural Elements and Receptor Phosphorylation Determines Arrestin-3 Interaction with the Free Fatty Acid Receptor FFA4

por Butcher, Adrian J., Hudson, Brian D., Shimpukade, Bharat, Alvarez-Curto, Elisa, Prihandoko, Rudi, Ulven, Trond, Milligan, Graeme, Tobin, Andrew B.
Publicado 2014

Differential G-protein-coupled Receptor Phosphorylation Provides Evidence for a Signaling Bar Code

por Butcher, Adrian J., Prihandoko, Rudi, Kong, Kok Choi, McWilliams, Phillip, Edwards, Jennifer M., Bottrill, Andrew, Mistry, Sharad, Tobin, Andrew B.
Publicado 2011

Design, Synthesis, and Evaluation of a Diazirine Photoaffinity Probe for Ligand-Based Receptor Capture Targeting G Protein–Coupled Receptors

por Müskens, Frederike M., Ward, Richard J., Herkt, Dominik, van de Langemheen, Helmus, Tobin, Andrew B., Liskamp, Rob M. J., Milligan, Graeme
Publicado 2019