Evaluation of the Relationship between Clonal Hematopoiesis and Severe COVID-19 Disease in Rhesus Macaques

por Shin, Taehoon, Zhou, Yifan, Hong, So Gun, Todd, John-Paul, Andrew, Shayne, Flynn, Barbara, Gagne, Matthew, Moore, Ian, Cook, Anthony, Lewis, Mark, Foulds, Kathryn, Seder, Robert, Douek, Daniel, Roederer, Mario, Dunbar, Cynthia E.
Publicado 2021

Anti-viral efficacy of a next-generation CD4-binding site bNAb in SHIV-infected animals in the absence of anti-drug antibody responses

por Lovelace, Sarah E., Helmold Hait, Sabrina, Yang, Eun Sung, Fox, Madison L., Liu, Cuiping, Choe, Misook, Chen, Xuejun, McCarthy, Elizabeth, Todd, John-Paul, Woodward, Ruth A., Koup, Richard A., Mascola, John R., Pegu, Amarendra
Publicado 2022

Vectored delivery of anti-SIV envelope targeting mAb via AAV8 protects rhesus macaques from repeated limiting dose intrarectal swarm SIVsmE660 challenge

por Welles, Hugh C., Jennewein, Madeleine F., Mason, Rosemarie D., Narpala, Sandeep, Wang, Lingshu, Cheng, Cheng, Zhang, Yi, Todd, John-Paul, Lifson, Jeffrey D., Balazs, Alejandro B., Alter, Galit, McDermott, Adrian B., Mascola, John R., Roederer, Mario
Publicado 2018

Investigation of the impact of clonal hematopoiesis on severity and pathophysiology of COVID-19 in rhesus macaques

por Shin, Tae-Hoon, Zhou, Yifan, Lee, Byung-Chul, Hong, So Gun, Andrew, Shayne F., Flynn, Barbara J., Gagne, Matthew, Todd, John-Paul M., Moore, Ian N., Cook, Anthony, Lewis, Mark G., Foulds, Kathryn E., Seder, Robert A., Douek, Daniel C., Roederer, Mario, Dunbar, Cynthia E.
Publicado 2023

Rational Design of an Epstein-Barr Virus Vaccine Targeting the Receptor-Binding Site

por Kanekiyo, Masaru, Bu, Wei, Joyce, M. Gordon, Meng, Geng, Whittle, James R.R., Baxa, Ulrich, Yamamoto, Takuya, Narpala, Sandeep, Todd, John-Paul, Rao, Srinivas S., McDermott, Adrian B., Koup, Richard A., Rossmann, Michael G., Mascola, John R., Graham, Barney S., Cohen, Jeffrey I., Nabel, Gary J.
Publicado 2015

Activation and lysis of human CD4 cells latently infected with HIV-1

por Pegu, Amarendra, Asokan, Mangaiarkarasi, Wu, Lan, Wang, Keyun, Hataye, Jason, Casazza, Joseph P., Guo, Xiaoti, Shi, Wei, Georgiev, Ivelin, Zhou, Tongqing, Chen, Xuejun, O'Dell, Sijy, Todd, John-Paul, Kwong, Peter D., Rao, Srinivas S., Yang, Zhi-yong, Koup, Richard A., Mascola, John R., Nabel, Gary J.
Publicado 2015

Structure-based design of a single-chain triple-disulfide-stabilized fusion-glycoprotein trimer that elicits high-titer neutralizing responses against human metapneumovirus

por Ou, Li, Chen, Steven J., Teng, I-Ting, Yang, Lijuan, Zhang, Baoshan, Zhou, Tongqing, Biju, Andrea, Cheng, Cheng, Kong, Wing-Pui, Morano, Nicholas C., Stancofski, Erik-Stephane D., Todd, John-Paul, Tsybovsky, Yaroslav, Wang, Shuishu, Zheng, Cheng-Yan, Mascola, John R., Shapiro, Lawrence, Woodward, Ruth A., Buchholz, Ursula J., Kwong, Peter D.
Publicado 2023

Development of an In Vivo Probe to Track SARS-CoV-2 Infection in Rhesus Macaques

por Madden, Patrick J., Arif, Muhammad S., Becker, Mark E., McRaven, Michael D., Carias, Ann M., Lorenzo-Redondo, Ramon, Xiao, Sixia, Midkiff, Cecily C., Blair, Robert V., Potter, Elizabeth Lake, Martin-Sancho, Laura, Dodson, Alan, Martinelli, Elena, Todd, John-Paul M., Villinger, Francois J., Chanda, Sumit K., Aye, Pyone Pyone, Roy, Chad J., Roederer, Mario, Lewis, Mark G., Veazey, Ronald S., Hope, Thomas J.
Publicado 2021

Trispecific antibody targeting HIV-1 and T cells activates and eliminates latently-infected cells in HIV/SHIV infections

por Promsote, Wanwisa, Xu, Ling, Hataye, Jason, Fabozzi, Giulia, March, Kylie, Almasri, Cassandra G., DeMouth, Megan E., Lovelace, Sarah E., Talana, Chloe Adrienna, Doria-Rose, Nicole A., McKee, Krisha, Hait, Sabrina Helmold, Casazza, Joseph P., Ambrozak, David, Beninga, Jochen, Rao, Ercole, Furtmann, Norbert, Birkenfeld, Joerg, McCarthy, Elizabeth, Todd, John-Paul, Petrovas, Constantinos, Connors, Mark, Hebert, Andrew T., Beck, Jeremy, Shen, Junqing, Zhang, Bailin, Levit, Mikhail, Wei, Ronnie R., Yang, Zhi-yong, Pegu, Amarendra, Mascola, John R., Nabel, Gary J., Koup, Richard A.
Publicado 2023

Surface-Matrix Screening Identifies Semi-specific Interactions that Improve Potency of a Near Pan-reactive HIV-1-Neutralizing Antibody

por Kwon, Young D., Chuang, Gwo-Yu, Zhang, Baoshan, Bailer, Robert T., Doria-Rose, Nicole A., Gindin, Tatyana S., Lin, Bob, Louder, Mark K., McKee, Krisha, O’Dell, Sijy, Pegu, Amarendra, Schmidt, Stephen D., Asokan, Mangaiarkarasi, Chen, Xuejun, Choe, Misook, Georgiev, Ivelin S., Jin, Vivian, Pancera, Marie, Rawi, Reda, Wang, Keyun, Chaudhuri, Rajoshi, Kueltzo, Lisa A., Manceva, Slobodanka D., Todd, John-Paul, Scorpio, Diana G., Kim, Mikyung, Reinherz, Ellis L., Wagh, Kshitij, Korber, Bette M., Connors, Mark, Shapiro, Lawrence, Mascola, John R., Kwong, Peter D.
Publicado 2018

Immunological and Virological Mechanisms of Vaccine-Mediated Protection Against SIV and HIV

por Roederer, Mario, Keele, Brandon F., Schmidt, Stephen D., Mason, Rosemarie D., Welles, Hugh C., Fischer, Will, Labranche, Celia, Foulds, Kathryn E., Louder, Mark K., Yang, Zhi-Yong, Todd, John-Paul M., Buzby, Adam P., Mach, Linh V., Shen, Ling, Seaton, Kelly E., Ward, Brandy M., Bailer, Robert T., Gottardo, Raphael, Gu, Wenjuan, Ferrari, Guido, Alam, S. Munir, Denny, Thomas N., Montefiori, David C., Tomaras, Georgia D., Korber, Bette T., Nason, Martha C., Seder, Robert A., Koup, Richard A., Letvin, Norman L., Rao, Srinivas S., Nabel, Gary J., Mascola, John R.
Publicado 2013

Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1

por Xu, Kai, Acharya, Priyamvada, Kong, Rui, Cheng, Cheng, Chuang, Gwo-Yu, Liu, Kevin, Louder, Mark K., O’Dell, Sijy, Rawi, Reda, Sastry, Mallika, Shen, Chen-Hsiang, Zhang, Baoshan, Zhou, Tongqing, Asokan, Mangaiarkarasi, Bailer, Robert T., Chambers, Michael, Chen, Xuejun, Choi, Chang W., Dandey, Venkata P., Doria-Rose, Nicole A., Druz, Aliaksandr, Eng, Edward T., Farney, Katie, Foulds, Kathryn E., Geng, Hui, Georgiev, Ivelin S., Gorman, Jason, Hill, Kurt R., Jafari, Alexander J., Kwon, Young D., Lai, Yen-Ting, Lemmin, Thomas, McKee, Krisha, Ohr, Tiffany Y., Ou, Li, Peng, Dongjun, Rowshan, Ariana P., Sheng, Zizhang, Todd, John-Paul, Tsybovsky, Yaroslav, Viox, Elise G., Wang, Yiran, Wei, Hui, Yang, Yongping, Zhou, Amy F., Chen, Rui, Yang, Lu, Scorpio, Diana G., McDermott, Adrian B., Shapiro, Lawrence, Carragher, Bridget, Potter, Clinton S., Mascola, John R., Kwong, Peter D.
Publicado 2018

mRNA-1273 Protects against SARS-CoV-2 Beta Infection in Nonhuman Primates

por Corbett, Kizzmekia S., Werner, Anne P., O’ Connell, Sarah, Gagne, Matthew, Lai, Lilin, Moliva, Juan I., Flynn, Barbara, Choi, Angela, Koch, Matthew, Foulds, Kathryn E., Andrew, Shayne F., Flebbe, Dillon R., Lamb, Evan, Nurmukhambetova, Saule T., Provost, Samantha J., Bock, Kevin W., Minai, Mahnaz, Nagata, Bianca M., Van Ry, Alex, Flinchbaugh, Zackery, Johnston, Timothy S., Mokhtari, Elham Bayat, Mudvari, Prakriti, Henry, Amy R., Laboune, Farida, Chang, Becky, Porto, Maciel, Wear, Jaclyn, Alvarado, Gabriela S., Boyoglu-Barnum, Seyhan, Todd, John-Paul M., Bart, Bridget, Cook, Anthony, Dodson, Alan, Pessaint, Laurent, Steingrebe, Katelyn, Elbashir, Sayda, Sriparna, Manjari, Pekosz, Andrew, Andersen, Hanne, Wu, Kai, Edwards, Darin K., Kar, Swagata, Lewis, Mark G., Boritz, Eli, Moore, Ian N., Carfi, Andrea, Suthar, Mehul S., McDermott, Adrian, Roederer, Mario, Nason, Martha C., Sullivan, Nancy J., Douek, Daniel C., Graham, Barney S., Seder, Robert A.
Publicado 2021

Protection from SARS-CoV-2 Delta one year after mRNA-1273 vaccination in rhesus macaques coincides with anamnestic antibody response in the lung

por Gagne, Matthew, Corbett, Kizzmekia S., Flynn, Barbara J., Foulds, Kathryn E., Wagner, Danielle A., Andrew, Shayne F., Todd, John-Paul M., Honeycutt, Christopher Cole, McCormick, Lauren, Nurmukhambetova, Saule T., Davis-Gardner, Meredith E., Pessaint, Laurent, Bock, Kevin W., Nagata, Bianca M., Minai, Mahnaz, Werner, Anne P., Moliva, Juan I., Tucker, Courtney, Lorang, Cynthia G., Zhao, Bingchun, McCarthy, Elizabeth, Cook, Anthony, Dodson, Alan, Teng, I-Ting, Mudvari, Prakriti, Roberts-Torres, Jesmine, Laboune, Farida, Wang, Lingshu, Goode, Adrienne, Kar, Swagata, Boyoglu-Barnum, Seyhan, Yang, Eun Sung, Shi, Wei, Ploquin, Aurélie, Doria-Rose, Nicole, Carfi, Andrea, Mascola, John R., Boritz, Eli A., Edwards, Darin K., Andersen, Hanne, Lewis, Mark G., Suthar, Mehul S., Graham, Barney S., Roederer, Mario, Moore, Ian N., Nason, Martha C., Sullivan, Nancy J., Douek, Daniel C., Seder, Robert A.
Publicado 2022

Vaccination with SARS-CoV-2 Spike Protein and AS03 Adjuvant Induces Rapid Anamnestic Antibodies in the Lung and Protects Against Virus Challenge in Nonhuman Primates

por Francica, Joseph R., Flynn, Barbara J., Foulds, Kathryn E., Noe, Amy T., Werner, Anne P., Moore, Ian N., Gagne, Matthew, Johnston, Timothy S., Tucker, Courtney, Davis, Rachel L., Flach, Britta, O’Connell, Sarah, Andrew, Shayne F., Lamb, Evan, Flebbe, Dillon R., Nurmukhambetova, Saule T., Donaldson, Mitzi M., Todd, John-Paul M., Zhu, Alex Lee, Atyeo, Caroline, Fischinger, Stephanie, Gorman, Matthew J, Shin, Sally, Edara, Venkata Viswanadh, Floyd, Katharine, Lai, Lilin, Tylor, Alida, McCarthy, Elizabeth, Lecouturier, Valerie, Ruiz, Sophie, Berry, Catherine, Tibbitts, Timothy, Andersen, Hanne, Cook, Anthony, Dodson, Alan, Pessaint, Laurent, Ry, Alex Van, Koutsoukos, Marguerite, Gutzeit, Cindy, Teng, I-Ting, Zhou, Tongqing, Li, Dapeng, Haynes, Barton F., Kwong, Peter D., McDermott, Adrian, Lewis, Mark G., Fu, Tong Ming, Chicz, Roman, van der Most, Robbert, Corbett, Kizzmekia S., Suthar, Mehul S., Alter, Galit, Roederer, Mario, Sullivan, Nancy J., Douek, Daniel C., Graham, Barney S., Casimiro, Danilo, Seder, Robert A.
Publicado 2021

Protective antibodies elicited by SARS-CoV-2 spike protein vaccination are boosted in the lung after challenge in nonhuman primates

por Francica, Joseph R., Flynn, Barbara J., Foulds, Kathryn E., Noe, Amy T., Werner, Anne P., Moore, Ian N., Gagne, Matthew, Johnston, Timothy S., Tucker, Courtney, Davis, Rachel L., Flach, Britta, O’Connell, Sarah, Andrew, Shayne F., Lamb, Evan, Flebbe, Dillon R., Nurmukhambetova, Saule T., Donaldson, Mitzi M., Todd, John-Paul M., Zhu, Alex Lee, Atyeo, Caroline, Fischinger, Stephanie, Gorman, Matthew J, Shin, Sally, Edara, Venkata Viswanadh, Floyd, Katharine, Lai, Lilin, Boyoglu-Barnum, Seyhan, Van De Wetering, Renee, Tylor, Alida, McCarthy, Elizabeth, Lecouturier, Valerie, Ruiz, Sophie, Berry, Catherine, Tibbitts, Timothy, Andersen, Hanne, Cook, Anthony, Dodson, Alan, Pessaint, Laurent, Van Ry, Alex, Koutsoukos, Marguerite, Gutzeit, Cindy, Teng, I.-Ting, Zhou, Tongqing, Li, Dapeng, Haynes, Barton F., Kwong, Peter D., McDermott, Adrian, Lewis, Mark G., Fu, Tong Ming, Chicz, Roman, van der Most, Robbert, Corbett, Kizzmekia S., Suthar, Mehul S., Alter, Galit, Roederer, Mario, Sullivan, Nancy J., Douek, Daniel C., Graham, Barney S., Casimiro, Danilo, Seder, Robert A.
Publicado 2021

Evaluation of the mRNA-1273 Vaccine against SARS-CoV-2 in Nonhuman Primates

por Corbett, Kizzmekia S., Flynn, Barbara, Foulds, Kathryn E., Francica, Joseph R., Boyoglu-Barnum, Seyhan, Werner, Anne P., Flach, Britta, O’Connell, Sarah, Bock, Kevin W., Minai, Mahnaz, Nagata, Bianca M., Andersen, Hanne, Martinez, David R., Noe, Amy T., Douek, Naomi, Donaldson, Mitzi M., Nji, Nadesh N., Alvarado, Gabriela S., Edwards, Darin K., Flebbe, Dillon R., Lamb, Evan, Doria-Rose, Nicole A., Lin, Bob C., Louder, Mark K., O’Dell, Sijy, Schmidt, Stephen D., Phung, Emily, Chang, Lauren A., Yap, Christina, Todd, John-Paul M., Pessaint, Laurent, Van Ry, Alex, Browne, Shanai, Greenhouse, Jack, Putman-Taylor, Tammy, Strasbaugh, Amanda, Campbell, Tracey-Ann, Cook, Anthony, Dodson, Alan, Steingrebe, Katelyn, Shi, Wei, Zhang, Yi, Abiona, Olubukola M., Wang, Lingshu, Pegu, Amarendra, Yang, Eun Sung, Leung, Kwanyee, Zhou, Tongqing, Teng, I-Ting, Widge, Alicia, Gordon, Ingelise, Novik, Laura, Gillespie, Rebecca A., Loomis, Rebecca J., Moliva, Juan I., Stewart-Jones, Guillaume, Himansu, Sunny, Kong, Wing-Pui, Nason, Martha C., Morabito, Kaitlyn M., Ruckwardt, Tracy J., Ledgerwood, Julie E., Gaudinski, Martin R., Kwong, Peter D., Mascola, John R., Carfi, Andrea, Lewis, Mark G., Baric, Ralph S., McDermott, Adrian, Moore, Ian N., Sullivan, Nancy J., Roederer, Mario, Seder, Robert A., Graham, Barney S.
Publicado 2020

mRNA-1273 or mRNA-Omicron boost in vaccinated macaques elicits similar B cell expansion, neutralizing responses, and protection from Omicron

por Gagne, Matthew, Moliva, Juan I., Foulds, Kathryn E., Andrew, Shayne F., Flynn, Barbara J., Werner, Anne P., Wagner, Danielle A., Teng, I-Ting, Lin, Bob C., Moore, Christopher, Jean-Baptiste, Nazaire, Carroll, Robin, Foster, Stephanie L., Patel, Mit, Ellis, Madison, Edara, Venkata-Viswanadh, Maldonado, Nahara Vargas, Minai, Mahnaz, McCormick, Lauren, Honeycutt, Christopher Cole, Nagata, Bianca M., Bock, Kevin W., Dulan, Caitlyn N.M., Cordon, Jamilet, Flebbe, Dillon R., Todd, John-Paul M., McCarthy, Elizabeth, Pessaint, Laurent, Van Ry, Alex, Narvaez, Brandon, Valentin, Daniel, Cook, Anthony, Dodson, Alan, Steingrebe, Katelyn, Nurmukhambetova, Saule T., Godbole, Sucheta, Henry, Amy R., Laboune, Farida, Roberts-Torres, Jesmine, Lorang, Cynthia G., Amin, Shivani, Trost, Jessica, Naisan, Mursal, Basappa, Manjula, Willis, Jacquelyn, Wang, Lingshu, Shi, Wei, Doria-Rose, Nicole A., Zhang, Yi, Yang, Eun Sung, Leung, Kwanyee, O’Dell, Sijy, Schmidt, Stephen D., Olia, Adam S., Liu, Cuiping, Harris, Darcy R., Chuang, Gwo-Yu, Stewart-Jones, Guillaume, Renzi, Isabella, Lai, Yen-Ting, Malinowski, Agata, Wu, Kai, Mascola, John R., Carfi, Andrea, Kwong, Peter D., Edwards, Darin K., Lewis, Mark G., Andersen, Hanne, Corbett, Kizzmekia S., Nason, Martha C., McDermott, Adrian B., Suthar, Mehul S., Moore, Ian N., Roederer, Mario, Sullivan, Nancy J., Douek, Daniel C., Seder, Robert A.
Publicado 2022