An optimal ubiquitin-proteasome pathway in the nervous system: the role of deubiquitinating enzymes

por Ristic, Gorica, Tsou, Wei-Ling, Todi, Sokol V.
Publicado 2014

Unanchored Ubiquitin Chains, Revisited

por Blount, Jessica R., Johnson, Sean L., Todi, Sokol V.
Publicado 2020

Isoleucine 44 Hydrophobic Patch Controls Toxicity of Unanchored, Linear Ubiquitin Chains through NF-κB Signaling

por Blount, Jessica R., Libohova, Kozeta, Silva, Gustavo M., Todi, Sokol V.
Publicado 2020

Alpha- and beta-adrenergic octopamine receptors in muscle and heart are required for Drosophila exercise adaptations

por Sujkowski, Alyson, Gretzinger, Anna, Soave, Nicolette, Todi, Sokol V., Wessells, Robert
Publicado 2020

Regional and age-dependent changes in ubiquitination in cellular and mouse models of spinocerebellar ataxia type 3

por Luo, Haiyang, Todi, Sokol V., Paulson, Henry L., Costa, Maria do Carmo
Publicado 2023

Inhibition of alpha-synuclein aggregation by multifunctional dopamine agonists assessed by a novel in vitro assay and an in vivo Drosophila synucleinopathy model

por Yedlapudi, Deepthi, Joshi, Gnanada S., Luo, Dan, Todi, Sokol V., Dutta, Aloke K.
Publicado 2016

Phenotypic defects from the expression of wild-type and pathogenic TATA-binding proteins in new Drosophila models of Spinocerebellar Ataxia Type 17

por Patel, Nikhil, Alam, Nadir, Libohova, Kozeta, Dulay, Ryan, Todi, Sokol V, Sujkowski, Alyson
Publicado 2023

Ubiquitin-Specific Protease 25 Functions in Endoplasmic Reticulum-Associated Degradation

por Blount, Jessica R., Burr, Aaron A., Denuc, Amanda, Marfany, Gemma, Todi, Sokol V.
Publicado 2012

Ubiquitin-interacting motifs of ataxin-3 regulate its polyglutamine toxicity through Hsc70-4-dependent aggregation

por Johnson, Sean L, Ranxhi, Bedri, Libohova, Kozeta, Tsou, Wei-Ling, Todi, Sokol V
Publicado 2020

Endurance exercise ameliorates phenotypes in Drosophila models of spinocerebellar ataxias

por Sujkowski, Alyson, Richardson, Kristin, Prifti, Matthew V, Wessells, Robert J, Todi, Sokol V
Publicado 2022

Myosin VIIA, Important for Human Auditory Function, Is Necessary for Drosophila Auditory Organ Development

por Todi, Sokol V., Sivan-Loukianova, Elena, Jacobs, Julie S., Kiehart, Daniel P., Eberl, Daniel F.
Publicado 2008

Expression and Regulation of Deubiquitinase-Resistant, Unanchored Ubiquitin Chains in Drosophila

por Blount, Jessica R., Libohova, Kozeta, Marsh, Gregory B., Sutton, Joanna R., Todi, Sokol V.
Publicado 2018

Ubiquitin-binding site 1 of pathogenic ataxin-3 regulates its toxicity in Drosophila models of Spinocerebellar Ataxia Type 3

por Prifti, Matthew V., Libohova, Kozeta, Harris, Autumn L., Tsou, Wei-Ling, Todi, Sokol V.
Publicado 2023

Polyglutamine length-dependent toxicity from α1ACT in Drosophila models of spinocerebellar ataxia type 6

por Tsou, Wei-Ling, Qiblawi, Sultan H., Hosking, Ryan R., Gomez, Christopher M., Todi, Sokol V.
Publicado 2016

Targeting alpha synuclein and amyloid beta by a multifunctional, brain-penetrant dopamine D2/D3 agonist D-520: Potential therapeutic application in Parkinson’s disease with dementi...

por Yedlapudi, Deepthi, Xu, Liping, Luo, Dan, Marsh, Gregory B., Todi, Sokol V., Dutta, Aloke K.
Publicado 2019

A survey of protein interactions and posttranslational modifications that influence the polyglutamine diseases

por Johnson, Sean L., Tsou, Wei-Ling, Prifti, Matthew V., Harris, Autumn L., Todi, Sokol V.
Publicado 2022

Editorial: The role of posttranslational modifications in polyglutamine diseases

por Weber, Jonasz Jeremiasz, Costa, Maria do Carmo, Scaglione, K. Matthew, Todi, Sokol V., Nguyen, Huu Phuc
Publicado 2023

Progressive degeneration in a new Drosophila model of Spinocerebellar Ataxia type 7

por Sujkowski, Alyson L., Ranxhi, Bedri, Prifti, Matthew V., Alam, Nadir, Todi, Sokol V., Tsou, Wei-Ling
Publicado 2023

Understanding the Role of the Josephin Domain in the PolyUb Binding and Cleavage Properties of Ataxin-3

por Nicastro, Giuseppe, Todi, Sokol V., Karaca, Ezgi, Bonvin, Alexandre M. J. J., Paulson, Henry L., Pastore, Annalisa
Publicado 2010

Opioid Deaths: Trends, Biomarkers, and Potential Drug Interactions Revealed by Decision Tree Analyses

por Saad, Manal H., Savonen, Candace L., Rumschlag, Matthew, Todi, Sokol V., Schmidt, Carl J., Bannon, Michael J.
Publicado 2018