NF-κB promotes the stem-like properties of leukemia cells by activation of LIN28B

por Zhou, Jianbiao, Chooi, Jing-Yuan, Ching, Ying Qing, Quah, Jessie Yiying, Toh, Sabrina Hui-Min, Ng, Yvonne, Tan, Tuan Zea, Chng, Wee-Joo
Publicado 2018

A loss-of-function genetic screening reveals synergistic targeting of AKT/mTOR and WTN/β-catenin pathways for treatment of AML with high PRL-3 phosphatase

por Zhou, Jianbiao, Toh, Sabrina Hui-Min, Chan, Zit-Liang, Quah, Jessie Yiying, Chooi, Jing-Yuan, Tan, Tuan Zea, Chong, Phyllis S. Y., Zeng, Qi, Chng, Wee-Joo
Publicado 2018

Inhibition of LIN28B impairs leukemia cell growth and metabolism in acute myeloid leukemia

por Zhou, Jianbiao, Bi, Chonglei, Ching, Ying Qing, Chooi, Jing-Yuan, Lu, Xiao, Quah, Jessie Yiying, Toh, Sabrina Hui-Min, Chan, Zit-Liang, Tan, Tuan Zea, Chong, Phyllis SY, Chng, Wee-Joo
Publicado 2017

ASLAN003, a potent dihydroorotate dehydrogenase inhibitor for differentiation of acute myeloid leukemia

por Zhou, Jianbiao, Quah, Jessie Yiying, Ng, Yvonne, Chooi, Jing-Yuan, Toh, Sabrina Hui-Min, Lin, Baohong, Tan, Tuan Zea, Hosoi, Hiroki, Osato, Motomi, Seet, Qihui, Ooi, A.G. Lisa, Lindmark, Bertil, McHale, Mark, Chng, Wee-Joo
Publicado 2019

Determinants of response to daratumumab in Epstein-Barr virus-positive natural killer and T-cell lymphoma

por Mustafa, Nurulhuda, Nee, Adina Huey Fang, Chooi, Jing Yuan, Toh, Sabrina Hui Min, Chung, Tae-Hoon, Selvarajan, Viknesvaran, Fan, Shuangyi, Ng, Siok Bian, Poon, Michelle, Chan, Esther, Lee, Joanne, Chee, Yen Lin, Jeyasekharan, Anand D, Zhou, Longen, Yang, Jennifer, Chng, Wee Joo
Publicado 2021

Super-enhancer-driven TOX2 mediates oncogenesis in Natural Killer/T Cell Lymphoma

por Zhou, Jianbiao, Toh, Sabrina Hui-Min, Tan, Tze King, Balan, Kalpnaa, Lim, Jing Quan, Tan, Tuan Zea, Xiong, Sinan, Jia, Yunlu, Ng, Siok-Bian, Peng, Yanfen, Jeyasekharan, Anand D., Fan, Shuangyi, Lim, Soon Thye, Ong, Chin-Ann Johnny, Ong, Choon Kiat, Sanda, Takaomi, Chng, Wee-Joo
Publicado 2023