Endoplasmic reticulum stress and eIF2α phosphorylation: The Achilles heel of pancreatic β cells

por Cnop, Miriam, Toivonen, Sanna, Igoillo-Esteve, Mariana, Salpea, Paraskevi
Publicado 2017

Intestinal Commitment and Maturation of Human Pluripotent Stem Cells Is Independent of Exogenous FGF4 and R-spondin1

por Tamminen, Kaisa, Balboa, Diego, Toivonen, Sanna, Pakarinen, Mikko P., Wiener, Zoltan, Alitalo, Kari, Otonkoski, Timo
Publicado 2015

A Novel Feeder-Free Culture System for Human Pluripotent Stem Cell Culture and Induced Pluripotent Stem Cell Derivation

por Vuoristo, Sanna, Toivonen, Sanna, Weltner, Jere, Mikkola, Milla, Ustinov, Jarkko, Trokovic, Ras, Palgi, Jaan, Lund, Riikka, Tuuri, Timo, Otonkoski, Timo
Publicado 2013

Selective MicroRNA-Offset RNA Expression in Human Embryonic Stem Cells

por Asikainen, Suvi, Heikkinen, Liisa, Juhila, Juuso, Holm, Frida, Weltner, Jere, Trokovic, Ras, Mikkola, Milla, Toivonen, Sanna, Balboa, Diego, Lampela, Riina, Icay, Katherine, Tuuri, Timo, Otonkoski, Timo, Wong, Garry, Hovatta, Outi
Publicado 2015

Stearoyl CoA desaturase is a gatekeeper that protects human beta cells against lipotoxicity and maintains their identity

por Oshima, Masaya, Pechberty, Séverine, Bellini, Lara, Göpel, Sven O., Campana, Mélanie, Rouch, Claude, Dairou, Julien, Cosentino, Cristina, Fantuzzi, Federica, Toivonen, Sanna, Marchetti, Piero, Magnan, Christophe, Cnop, Miriam, Le Stunff, Hervé, Scharfmann, Raphaël
Publicado 2019

In depth functional characterization of human induced pluripotent stem cell-derived beta cells in vitro and in vivo

por Fantuzzi, Federica, Toivonen, Sanna, Schiavo, Andrea Alex, Chae, Heeyoung, Tariq, Mohammad, Sawatani, Toshiaki, Pachera, Nathalie, Cai, Ying, Vinci, Chiara, Virgilio, Enrico, Ladriere, Laurence, Suleiman, Mara, Marchetti, Piero, Jonas, Jean-Christophe, Gilon, Patrick, Eizirik, Décio L., Igoillo-Esteve, Mariana, Cnop, Miriam
Publicado 2022

Pancreatic β-cell tRNA hypomethylation and fragmentation link TRMT10A deficiency with diabetes

por Cosentino, Cristina, Toivonen, Sanna, Diaz Villamil, Esteban, Atta, Mohamed, Ravanat, Jean-Luc, Demine, Stéphane, Schiavo, Andrea Alex, Pachera, Nathalie, Deglasse, Jean-Philippe, Jonas, Jean-Christophe, Balboa, Diego, Otonkoski, Timo, Pearson, Ewan R, Marchetti, Piero, Eizirik, Décio L, Cnop, Miriam, Igoillo-Esteve, Mariana
Publicado 2018

GLP-1R agonists demonstrate potential to treat Wolfram syndrome in human preclinical models

por Gorgogietas, Vyron, Rajaei, Bahareh, Heeyoung, Chae, Santacreu, Bruno J., Marín-Cañas, Sandra, Salpea, Paraskevi, Sawatani, Toshiaki, Musuaya, Anyishai, Arroyo, María N., Moreno-Castro, Cristina, Benabdallah, Khadija, Demarez, Celine, Toivonen, Sanna, Cosentino, Cristina, Pachera, Nathalie, Lytrivi, Maria, Cai, Ying, Carnel, Lode, Brown, Cris, Urano, Fumihiko, Marchetti, Piero, Gilon, Patrick, Eizirik, Decio L., Cnop, Miriam, Igoillo-Esteve, Mariana
Publicado 2023