LRRK2 at Striatal Synapses: Cell-Type Specificity and Mechanistic Insights

por Skelton, Patrick D., Tokars, Valerie, Parisiadou, Loukia
Publicado 2022

Evaluating the 3C-like protease activity of SARS-Coronavirus: Recommendations for standardized assays for drug discovery

por Grum-Tokars, Valerie, Ratia, Kiira, Begaye, Adrian, Baker, Susan C., Mesecar, Andrew D.
Publicado 2008

MnSOD Lysine 68 acetylation leads to cisplatin and doxorubicin resistance due to aberrant mitochondrial metabolism

por Gao, Yucheng, Zhu, Yueming, Tran, Elizabeth L., Tokars, Valerie, Dean, Angela E., Quan, Songhua, Gius, David
Publicado 2021

Energetic landscape of polycystin channel gating

por Ng, Leo CT, Harris, Brandon J, Larmore, Megan, Ta, My C, Vien, Thuy N, Tokars, Valerie L, Yarov‐Yarovoy, Vladimir, DeCaen, Paul G
Publicado 2023

Structure-based design, synthesis, and biological evaluation of peptidomimetic SARS-CoV 3CLpro inhibitors

por Ghosh, Arun K., Xi, Kai, Grum-Tokars, Valerie, Xu, Xiaoming, Ratia, Kiira, Fu, Wentao, Houser, Katherine V., Baker, Susan C., Johnson, Michael E., Mesecar, Andrew D.
Publicado 2007

Design, synthesis and antiviral efficacy of a series of potent chloropyridyl ester-derived SARS-CoV 3CLpro inhibitors

por Ghosh, Arun K., Gong, Gangli, Grum-Tokars, Valerie, Mulhearn, Debbie C., Baker, Susan C., Coughlin, Melissa, Prabhakar, Bellur S., Sleeman, Katrina, Johnson, Michael E., Mesecar, Andrew D.
Publicado 2008

Pneumococcal capsule expression is controlled through a conserved, distal cis-regulatory element during infection

por Glanville, David G., Gazioglu, Ozcan, Marra, Michela, Tokars, Valerie L., Kushnir, Tatyana, Habtom, Medhanie, Croucher, Nicholas J., Nebenzahl, Yaffa Mizrachi, Mondragón, Alfonso, Yesilkaya, Hasan, Ulijasz, Andrew T.
Publicado 2023

Discovery of N-(benzo[1,2,3]triazol-1-yl)-N-(benzyl)acetamido)phenyl) carboxamides as severe acute respiratory syndrome coronavirus (SARS-CoV) 3CLpro inhibitors: Identification of...

por Turlington, Mark, Chun, Aspen, Tomar, Sakshi, Eggler, Aimee, Grum-Tokars, Valerie, Jacobs, Jon, Daniels, J. Scott, Dawson, Eric, Saldanha, Adrian, Chase, Peter, Baez-Santos, Yahira M., Lindsley, Craig W., Hodder, Peter, Mesecar, Andrew D., Stauffer, Shaun R.
Publicado 2013

Targeting Human Central Nervous System Protein Kinases: An Isoform Selective p38αMAPK Inhibitor That Attenuates Disease Progression in Alzheimer’s Disease Mouse Models

por Roy, Saktimayee M., Grum-Tokars, Valerie L., Schavocky, James P., Saeed, Faisal, Staniszewski, Agnieszka, Teich, Andrew F., Arancio, Ottavio, Bachstetter, Adam D., Webster, Scott J., Van Eldik, Linda J., Minasov, George, Anderson, Wayne F., Pelletier, Jeffrey C., Watterson, D. Martin
Publicado 2015

Development of Novel In Vivo Chemical Probes to Address CNS Protein Kinase Involvement in Synaptic Dysfunction

por Watterson, D. Martin, Grum-Tokars, Valerie L., Roy, Saktimayee M., Schavocky, James P., Bradaric, Brinda Desai, Bachstetter, Adam D., Xing, Bin, Dimayuga, Edgardo, Saeed, Faisal, Zhang, Hong, Staniszewski, Agnieszka, Pelletier, Jeffrey C., Minasov, George, Anderson, Wayne F., Arancio, Ottavio, Van Eldik, Linda J.
Publicado 2013

Machine learning-assisted elucidation of CD81–CD44 interactions in promoting cancer stemness and extracellular vesicle integrity

por Ramos, Erika K, Tsai, Chia-Feng, Jia, Yuzhi, Cao, Yue, Manu, Megan, Taftaf, Rokana, Hoffmann, Andrew D, El-Shennawy, Lamiaa, Gritsenko, Marina A, Adorno-Cruz, Valery, Schuster, Emma J, Scholten, David, Patel, Dhwani, Liu, Xia, Patel, Priyam, Wray, Brian, Zhang, Youbin, Zhang, Shanshan, Moore, Ronald J, Mathews, Jeremy V, Schipma, Matthew J, Liu, Tao, Tokars, Valerie L, Cristofanilli, Massimo, Shi, Tujin, Shen, Yang, Dashzeveg, Nurmaa K, Liu, Huiping
Publicado 2022

Circulating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2

por El-Shennawy, Lamiaa, Hoffmann, Andrew D., Dashzeveg, Nurmaa Khund, McAndrews, Kathleen M., Mehl, Paul J., Cornish, Daphne, Yu, Zihao, Tokars, Valerie L., Nicolaescu, Vlad, Tomatsidou, Anastasia, Mao, Chengsheng, Felicelli, Christopher J., Tsai, Chia-Feng, Ostiguin, Carolina, Jia, Yuzhi, Li, Lin, Furlong, Kevin, Wysocki, Jan, Luo, Xin, Ruivo, Carolina F., Batlle, Daniel, Hope, Thomas J., Shen, Yang, Chae, Young Kwang, Zhang, Hui, LeBleu, Valerie S., Shi, Tujin, Swaminathan, Suchitra, Luo, Yuan, Missiakas, Dominique, Randall, Glenn C., Demonbreun, Alexis R., Ison, Michael G., Kalluri, Raghu, Fang, Deyu, Liu, Huiping
Publicado 2022