On the way to low-dose medicines

por Tolstikova, T. G., Tolstikov, A. G., Tolstikov, G. A.
Publicado 2007

Effect of Complexation with Arabinogalactan on Pharmacokinetics of “Guest” Drugs in Rats: For Example, Warfarin

por Khvostov, Mikhail V., Chernonosov, Alexander A., Tolstikova, Tatjana G., Kasakin, Marat F., Fedorova, Olga S., Dushkin, Alexander V.
Publicado 2013

Synthesis of Anti-Inflammatory Spirostene-Pyrazole Conjugates by a Consecutive Multicomponent Reaction of Diosgenin with Oxalyl Chloride, Arylalkynes and Hydrazines or Hydrazones

por Mironov, Maksim E., Borisov, Sergey A., Rybalova, Tatyana V., Baev, Dmitry S., Tolstikova, Tatyana G., Shults, Elvira E.
Publicado 2021

Betulinic Acid-Azaprostanoid Hybrids: Synthesis and Pharmacological Evaluation as Anti-inflammatory Agents

por Khlebnicova, Tatyana S., Piven, Yuri A., Lakhvich, Fedor A., Sorokina, Iryna V., Frolova, Tatiana S., Baev, Dmitry S., Tolstikova, Tatyana G.
Publicado 2020

Preparation of curcumin self-micelle solid dispersion with enhanced bioavailability and cytotoxic activity by mechanochemistry

por Zhang, Qihong, Polyakov, Nikolay E., Chistyachenko, Yulia S., Khvostov, Mikhail V., Frolova, Tatjana S., Tolstikova, Tatjana G., Dushkin, Alexandr V., Su, Weike
Publicado 2018

The Influence of Abiotic Stress Factors on the Morphophysiological and Phytochemical Aspects of the Acclimation of the Plant Rhodiola semenowii Boriss

por Terletskaya, Nina V., Korbozova, Nazym K., Kudrina, Nataliya O., Kobylina, Tatyana N., Kurmanbayeva, Meruert S., Meduntseva, Nataliya D., Tolstikova, Tatyana G.
Publicado 2021

Hybrides of Alkaloid Lappaconitine with Pyrimidine Motif on the Anthranilic Acid Moiety: Design, Synthesis, and Investigation of Antinociceptive Potency

por Cheremnykh, Kirill P., Savelyev, Victor A., Borisov, Sergey A., Ivanov, Igor D., Baev, Dmitry S., Tolstikova, Tatyana G., Vavilin, Valentin A., Shults, Elvira E.
Publicado 2020

Synthesis, Pharmacological Evaluation, and Molecular Modeling of Lappaconitine–1,5-Benzodiazepine Hybrids

por Cheremnykh, Kirill P., Bryzgalov, Arkadiy O., Baev, Dmitry S., Borisov, Sergey A., Sotnikova, Yulia S., Savelyev, Victor A., Tolstikova, Tatyana G., Sagdullaev, Shamansur S., Shults, Elvira E.
Publicado 2023

Design, Synthesis and Assay of Novel Methylxanthine–Alkynylmethylamine Derivatives as Acetylcholinesterase Inhibitors

por Reshetnikov, Danila V., Ivanov, Igor D., Baev, Dmitry S., Rybalova, Tatyana V., Mozhaitsev, Evgenii S., Patrushev, Sergey S., Vavilin, Valentin A., Tolstikova, Tatyana G., Shults, Elvira E.
Publicado 2022

Synthesis and Evaluation of Hypoglycemic Activity of Structural Isomers of ((Benzyloxy)phenyl)propanoic Acid Bearing an Aminobornyl Moiety

por Kuranov, Sergey O., Pon`kina, Darya A., Meshkova, Yulia V., Marenina, Mariya K., Khvostov, Mikhail V., Luzina, Olga A., Tolstikova, Tatiana G., Salakhutdinov, Nariman F.
Publicado 2023

Terpene-Containing Analogues of Glitazars as Potential Therapeutic Agents for Metabolic Syndrome

por Blokhin, Mikhail E., Kuranov, Sergey O., Khvostov, Mikhail V., Fomenko, Vladislav V., Luzina, Olga A., Zhukova, Natalia A., Elhajjar, Cham, Tolstikova, Tatiana G., Salakhutdinov, Nariman F.
Publicado 2023

Solubility, Permeability, Anti-Inflammatory Action and In Vivo Pharmacokinetic Properties of Several Mechanochemically Obtained Pharmaceutical Solid Dispersions of Nimesulide

por Wei, Wei, Evseenko, Veronica I., Khvostov, Mikhail V., Borisov, Sergey A., Tolstikova, Tatyana G., Polyakov, Nikolay E., Dushkin, Aleksandr V., Xu, Wenhao, Min, Lu, Su, Weike
Publicado 2021

Discovery of the First in Class 9-N-Berberine Derivative as Hypoglycemic Agent with Extra-Strong Action

por Khvostov, Mikhail V., Gladkova, Elizaveta D., Borisov, Sergey A., Zhukova, Nataliya A., Marenina, Mariya K., Meshkova, Yuliya V., Luzina, Olga A., Tolstikova, Tatijana G., Salakhutdinov, Nariman F.
Publicado 2021

Antihypothyroid Effect of Salidroside

por Korbozova, Nazym K., Kudrina, Nataliya O., Zhukova, Nataliya A., Grazhdannikov, Alexander E., Blavachinskaya, Irina V., Seitimova, Gulnaz A., Kulmanov, Timur E., Tolstikova, Tatyana G., Terletskaya, Nina V.
Publicado 2022

Investigation of 1,4-Substituted 1,2,3-Triazole Derivatives as Antiarrhythmics: Synthesis, Structure, and Properties

por Shestakova, Elena O., Il’yasov, Sergey G., Shchurova, Irina A., Glukhacheva, Vera S., Il’yasov, Dmitri S., Zhukov, Egor E., Bryzgalov, Arkady O., Tolstikova, Tatiana G., Gatilov, Yuri V.
Publicado 2022

Bornyl-Containing Derivatives of Benzyloxyphenylpropanoic Acid as FFAR1 Agonists: In Vitro and In Vivo Studies

por Pon’kina, Darya A., Kuranov, Sergey O., Marenina, Mariya K., Meshkova, Yulia V., Zhukova, Nataliya A., Khvostov, Mikhail V., Luzina, Olga A., Tolstikova, Tatiana G., Salakhutdinov, Nariman F.
Publicado 2023

Histological validation of fast macromolecular proton fraction mapping as a quantitative myelin imaging method in the cuprizone demyelination model

por Khodanovich, Marina Yu, Sorokina, Irina V., Glazacheva, Valentina Yu, Akulov, Andrey E., Nemirovich-Danchenko, Nikolay M., Romashchenko, Alexander V., Tolstikova, Tatyana G., Mustafina, Lilia R., Yarnykh, Vasily L.
Publicado 2017

Studies of the Specific Activity of Aerosolized Isoniazid against Tuberculosis in a Mouse Model

por Valiulin, Sergey V., Onischuk, Andrey A., Baklanov, Anatoly M., Dubtsov, Sergey N., Dultseva, Galina G., An’kov, Sergey V., Tolstikova, Tatiana G., Belogorodtsev, Sergey N., Schwartz, Yakov Sh.
Publicado 2022

Study of Hypoglycemic Activity of Novel 9-N-alkyltetrahydroberberine Derivatives

por Khvostov, Mikhail V., Gladkova, Elizaveta D., Borisov, Sergey A., Fedotova, Marina S., Zhukova, Nataliya A., Marenina, Mariya K., Meshkova, Yuliya V., Luzina, Olga A., Tolstikova, Tatiana G., Salakhutdinov, Nariman F.
Publicado 2022

Antiulcer Activity of Anthraquinone–Flavonoid Complex of Rumex tianschanicus Losinsk

por Seitimova, Gulnaz A., Shokan, Aksholpan K., Tolstikova, Tatyana G., Zhukova, Nataliya A., Korulkin, Dmitriy Yu., Kudrina, Nataliya O., Litvinenko, Yuliya A., Meduntseva, Nataliya D., Terletskaya, Nina V., Kulmanov, Timur E.
Publicado 2023