ATP as a multi-target danger signal in the brain

por Rodrigues, Ricardo J., Tomé, Angelo R., Cunha, Rodrigo A.
Publicado 2015

Functional distribution of Ca(2+)-coupled P2 purinergic receptors among adrenergic and noradrenergic bovine adrenal chromaffin cells

por Tomé, Ângelo R, Castro, Enrique, Santos, Rosa M, Rosário, Luís M
Publicado 2007

Selective stimulation of catecholamine release from bovine adrenal chromaffin cells by an ionotropic purinergic receptor sensitive to 2-methylthio ATP

por Tomé, Ângelo R, Castro, Enrique, Santos, Rosa M, Rosário, Luís M
Publicado 2007

Validation of an LC-MS/MS Method for the Quantification of Caffeine and Theobromine Using Non-Matched Matrix Calibration Curve

por Mendes, Vera M., Coelho, Margarida, Tomé, Angelo R., Cunha, Rodrigo A., Manadas, Bruno
Publicado 2019

Adenosine A(2A) Receptors Shut Down Adenosine A(1) Receptor-Mediated Presynaptic Inhibition to Promote Implementation of Hippocampal Long-Term Potentiation

por Lopes, Cátia R., Gonçalves, Francisco Q., Olaio, Simão, Tomé, Angelo R., Cunha, Rodrigo A., Lopes, João Pedro
Publicado 2023

Blockade of adenosine A(2A) receptors prevents interleukin-1β-induced exacerbation of neuronal toxicity through a p38 mitogen-activated protein kinase pathway

por Simões, Ana Patrícia, Duarte, João A, Agasse, Fabienne, Canas, Paula Margarida, Tomé, Angelo R, Agostinho, Paula, Cunha, Rodrigo A
Publicado 2012

Nicotinic α7 receptor activation selectively potentiates the function of NMDA receptors in glutamatergic terminals of the nucleus accumbens

por Zappettini, Stefania, Grilli, Massimo, Olivero, Guendalina, Chen, Jiayang, Padolecchia, Cristina, Pittaluga, Anna, Tomé, Angelo R., Cunha, Rodrigo A., Marchi, Mario
Publicado 2014

Simultaneous Alteration of the Circadian Variation of Memory, Hippocampal Synaptic Plasticity, and Metabolism in a Triple Transgenic Mouse Model of Alzheimer’s Disease

por Carvalho da Silva, António M., Lemos, Cristina, Silva, Henrique B., Ferreira, Ildete L., Tomé, Angelo R., Rego, A. Cristina, Cunha, Rodrigo A.
Publicado 2022

Crosstalk Between ATP-P(2X7) and Adenosine A(2A) Receptors Controlling Neuroinflammation in Rats Subject to Repeated Restraint Stress

por Dias, Liliana, Lopes, Cátia R., Gonçalves, Francisco Q., Nunes, Ana, Pochmann, Daniela, Machado, Nuno J., Tomé, Angelo R., Agostinho, Paula, Cunha, Rodrigo A.
Publicado 2021

Behavioral Phenotyping of Parkin-Deficient Mice: Looking for Early Preclinical Features of Parkinson's Disease

por Rial, Daniel, Castro, Adalberto A., Machado, Nuno, Garção, Pedro, Gonçalves, Francisco Q., Silva, Henrique B., Tomé, Ângelo R., Köfalvi, Attila, Corti, Olga, Raisman-Vozari, Rita, Cunha, Rodrigo A., Prediger, Rui D.
Publicado 2014

Neuromodulation and neuroprotective effects of chlorogenic acids in excitatory synapses of mouse hippocampal slices

por Fernandes, Mara Yone D., Dobrachinski, Fernando, Silva, Henrique B., Lopes, João Pedro, Gonçalves, Francisco Q., Soares, Felix A. A., Porciúncula, Lisiane O., Andrade, Geanne M., Cunha, Rodrigo A., Tomé, Angelo R.
Publicado 2021

Increased Synaptic ATP Release and CD73-Mediated Formation of Extracellular Adenosine in the Control of Behavioral and Electrophysiological Modifications Caused by Chronic Stress

por Dias, Liliana, Pochmann, Daniela, Lemos, Cristina, Silva, Henrique B., Real, Joana I., Gonçalves, Francisco Q., Rial, Daniel, Gonçalves, Nélio, Simões, Ana Patrícia, Ferreira, Samira G., Agostinho, Paula, Cunha, Rodrigo A., Tomé, Angelo R.
Publicado 2023

Adenosine A(2A) receptors control generalization of contextual fear in rats

por Simões, Ana P., Portes, Marina A. M., Lopes, Cátia R., Vanz, Felipe, Lourenço, Vanessa S., Pliássova, Anna, Gaspar, Ingride L., Silva, Henrique B., Tomé, Ângelo R., Canas, Paula M., Prediger, Rui D., Cunha, Rodrigo A.
Publicado 2023

Increased ATP Release and Higher Impact of Adenosine A(2A) Receptors on Corticostriatal Plasticity in a Rat Model of Presymptomatic Parkinson’s Disease

por Gonçalves, Francisco Q., Matheus, Filipe C., Silva, Henrique B., Real, Joana I., Rial, Daniel, Rodrigues, Ricardo J., Oses, Jean-Pierre, Silva, António C., Gonçalves, Nélio, Prediger, Rui D., Tomé, Ângelo R., Cunha, Rodrigo A.
Publicado 2022

Treatment with A(2A) receptor antagonist KW6002 and caffeine intake regulate microglia reactivity and protect retina against transient ischemic damage

por Boia, Raquel, Elvas, Filipe, Madeira, Maria H, Aires, Inês D, Rodrigues-Neves, Ana C, Tralhão, Pedro, Szabó, Eszter C, Baqi, Younis, Müller, Christa E, Tomé, Ângelo R, Cunha, Rodrigo A, Ambrósio, António F, Santiago, Ana R
Publicado 2017

Effects of Chronic Caffeine Consumption on Synaptic Function, Metabolism and Adenosine Modulation in Different Brain Areas

por Lopes, Cátia R., Oliveira, Andreia, Gaspar, Ingride, Rodrigues, Matilde S., Santos, Joana, Szabó, Eszter, Silva, Henrique B., Tomé, Ângelo R., Canas, Paula M., Agostinho, Paula, Carvalho, Rui A., Cunha, Rodrigo A., Simões, Ana Patrícia, Lopes, João Pedro, Ferreira, Samira G.
Publicado 2023

Downregulation of Sirtuin 1 Does Not Account for the Impaired Long-Term Potentiation in the Prefrontal Cortex of Female APPswe/PS1dE9 Mice Modelling Alzheimer’s Disease

por Lopes, Cátia R., Silva, Joana S., Santos, Joana, Rodrigues, Matilde S., Madeira, Daniela, Oliveira, Andreia, Moreira-de-Sá, Ana, Lourenço, Vanessa S., Gonçalves, Francisco Q., Silva, Henrique B., Simões, Ana Patrícia, Rolo, Anabela P., Canas, Paula M., Tomé, Ângelo R., Palmeira, Carlos M., Lopes, João Pedro, Cunha, Rodrigo A., Agostinho, Paula, Ferreira, Samira G.
Publicado 2023

Optogenetic activation of intracellular adenosine A(2A) receptor signaling in hippocampus is sufficient to trigger CREB phosphorylation and impair memory

por Li, Ping, Rial, Daniel, Canas, Paula M., Yoo, Ji-Hoon, Li, Wei, Zhou, Xiangtian, Wang, Yumei, van Westen, Gerard J.P., Payen, Marie-Pierre, Augusto, Elisabete, Gonçalves, Nélio, Tomé, Angelo R., Li, Zhihui, Wu, Zhongnan, Hou, Xianhua, Zhou, Yuanguo, IJzerman, Ad P., Boyden, Edward S., Cunha, Rodrigo A., Qu, Jia, Chen, Jiang-Fan
Publicado 2015