Dynamic CpG methylation delineates subregions within super-enhancers selectively decommissioned at the exit from naive pluripotency

por Bell, Emma, Curry, Edward W., Megchelenbrink, Wout, Jouneau, Luc, Brochard, Vincent, Tomaz, Rute A., Mau, King Hang T., Atlasi, Yaser, de Souza, Roshni A., Marks, Hendrik, Stunnenberg, Hendrik G., Jouneau, Alice, Azuara, Véronique
Publicado 2020

Method to Synchronize Cell Cycle of Human Pluripotent Stem Cells without Affecting Their Fundamental Characteristics

por Yiangou, Loukia, Grandy, Rodrigo A., Morell, Carola M., Tomaz, Rute A., Osnato, Anna, Kadiwala, Juned, Muraro, Daniele, Garcia-Bernardo, Jose, Nakanoh, Shota, Bernard, William G., Ortmann, Daniel, McCarthy, Davis J., Simonic, Ingrid, Sinha, Sanjay, Vallier, Ludovic
Publicado 2018

Generation of functional hepatocytes by forward programming with nuclear receptors

por Tomaz, Rute A, Zacharis, Ekaterini D, Bachinger, Fabian, Wurmser, Annabelle, Yamamoto, Daniel, Petrus-Reurer, Sandra, Morell, Carola M, Dziedzicka, Dominika, Wesley, Brandon T, Geti, Imbisaat, Segeritz, Charis-Patricia, de Brito, Miguel C, Chhatriwala, Mariya, Ortmann, Daniel, Saeb-Parsy, Kourosh, Vallier, Ludovic
Publicado 2022

Jmjd2c facilitates the assembly of essential enhancer-protein complexes at the onset of embryonic stem cell differentiation

por Tomaz, Rute A., Harman, Jennifer L., Karimlou, Donja, Weavers, Lauren, Fritsch, Lauriane, Bou-Kheir, Tony, Bell, Emma, del Valle Torres, Ignacio, Niakan, Kathy K., Fisher, Cynthia, Joshi, Onkar, Stunnenberg, Hendrik G., Curry, Edward, Ait-Si-Ali, Slimane, Jørgensen, Helle F., Azuara, Véronique
Publicado 2017

3D human liver tissue from pluripotent stem cells displays stable phenotype in vitro and supports compromised liver function in vivo

por Rashidi, Hassan, Luu, Nguyet-Thin, Alwahsh, Salamah M., Ginai, Maaria, Alhaque, Sharmin, Dong, Hua, Tomaz, Rute A., Vernay, Bertrand, Vigneswara, Vasanthy, Hallett, John M., Chandrashekran, Anil, Dhawan, Anil, Vallier, Ludovic, Bradley, Mark, Callanan, Anthony, Forbes, Stuart J., Newsome, Philip N., Hay, David C.
Publicado 2018

Naive Pluripotent Stem Cells Exhibit Phenotypic Variability that Is Driven by Genetic Variation

por Ortmann, Daniel, Brown, Stephanie, Czechanski, Anne, Aydin, Selcan, Muraro, Daniele, Huang, Yuanhua, Tomaz, Rute A., Osnato, Anna, Canu, Giovanni, Wesley, Brandon T., Skelly, Daniel A., Stegle, Oliver, Choi, Ted, Churchill, Gary A., Baker, Christopher L., Rugg-Gunn, Peter J., Munger, Steven C., Reinholdt, Laura G., Vallier, Ludovic
Publicado 2020

Regional Differences in Human Biliary Tissues and Corresponding In Vitro–Derived Organoids

por Rimland, Casey A., Tilson, Samantha G., Morell, Carola M., Tomaz, Rute A., Lu, Wei‐Yu, Adams, Simone E., Georgakopoulos, Nikitas, Otaizo‐Carrasquero, Francisco, Myers, Timothy G., Ferdinand, John R., Gieseck, Richard L., Sampaziotis, Fotios, Tysoe, Olivia C., Ross, Alexander, Kraiczy, Judith M., Wesley, Brandon, Muraro, Daniele, Zilbauer, Matthias, Oniscu, Gabriel C., Hannan, Nicholas R.F., Forbes, Stuart J., Saeb‐Parsy, Kourosh, Wynn, Thomas A., Vallier, Ludovic
Publicado 2021