Crystal Structure of the Formin mDia1 in Autoinhibited Conformation

por Otomo, Takanori, Tomchick, Diana R., Otomo, Chinatsu, Machius, Mischa, Rosen, Michael K.
Publicado 2010

Re-examining how complexin inhibits neurotransmitter release

por Trimbuch, Thorsten, Xu, Junjie, Flaherty, David, Tomchick, Diana R, Rizo, Josep, Rosenmund, Christian
Publicado 2014

High-resolution cryo-EM structures of the E. coli hemolysin ClyA oligomers

por Peng, Wei, de Souza Santos, Marcela, Li, Yang, Tomchick, Diana R., Orth, Kim
Publicado 2019

Molecular determinants for differential activation of the bile acid receptor from the pathogen Vibrio parahaemolyticus

por Zou, Angela J., Kinch, Lisa, Chimalapati, Suneeta, Garcia, Nalleli, Tomchick, Diana R., Orth, Kim
Publicado 2023

Structural insights for selective disruption of Beclin 1 binding to Bcl-2

por Pan, Yun-Zu, Liang, Qiren, Tomchick, Diana R., De Brabander, Jef K., Rizo, Josep
Publicado 2023

Mechanism of Actin Filament Nucleation by the Bacterial Effector VopL

por Yu, Bingke, Cheng, Hui-Chun, Brautigam, Chad A., Tomchick, Diana R., Rosen, Michael K.
Publicado 2011

Evidence for Posttranslational Protein Flavinylation in the Syphilis Spirochete Treponema pallidum: Structural and Biochemical Insights from the Catalytic Core of a Periplasmic Fla...

por Deka, Ranjit K., Brautigam, Chad A., Liu, Wei Z., Tomchick, Diana R., Norgard, Michael V.
Publicado 2015

Molecular insights into the enzymatic diversity of flavin‐trafficking protein (Ftp; formerly ApbE) in flavoprotein biogenesis in the bacterial periplasm

por Deka, Ranjit K., Brautigam, Chad A., Liu, Wei Z., Tomchick, Diana R., Norgard, Michael V.
Publicado 2015

SAV1 promotes Hippo kinase activation through antagonizing the PP2A phosphatase STRIPAK

por Bae, Sung Jun, Ni, Lisheng, Osinski, Adam, Tomchick, Diana R, Brautigam, Chad A, Luo, Xuelian
Publicado 2017

Structural Basis for a Munc13–1 Homodimer to Munc13–1/RIM Heterodimer Switch

por Lu, Jun, Machius, Mischa, Dulubova, Irina, Dai, Han, Südhof, Thomas C, Tomchick, Diana R, Rizo, Josep
Publicado 2006

Structure of cohesin subcomplex pinpoints direct shugoshin–Wapl antagonism in centromeric cohesion

por Hara, Kodai, Zheng, Ge, Qu, Qianhui, Liu, Hong, Ouyang, Zhuqing, Chen, Zhe, Tomchick, Diana R., Yu, Hongtao
Publicado 2014

Insights into Mad2 Regulation in the Spindle Checkpoint Revealed by the Crystal Structure of the Symmetric Mad2 Dimer

por Yang, Maojun, Li, Bing, Liu, Chyong-Jy, Tomchick, Diana R, Machius, Mischa, Rizo, Josep, Yu, Hongtao, Luo, Xuelian
Publicado 2008

Bile salt receptor complex activates a pathogenic type III secretion system

por Li, Peng, Rivera-Cancel, Giomar, Kinch, Lisa N, Salomon, Dor, Tomchick, Diana R, Grishin, Nick V, Orth, Kim
Publicado 2016

Alternative pathways utilize or circumvent putrescine for biosynthesis of putrescine-containing rhizoferrin

por Li, Bin, Deng, Xiaoyi, Kim, Sok Ho, Buhrow, Leann, Tomchick, Diana R., Phillips, Margaret A., Michael, Anthony J.
Publicado 2020

Relief of autoinhibition by conformational switch explains enzyme activation by a catalytically dead paralog

por Volkov, Oleg A, Kinch, Lisa, Ariagno, Carson, Deng, Xiaoyi, Zhong, Shihua, Grishin, Nick, Tomchick, Diana R, Chen, Zhe, Phillips, Margaret A
Publicado 2016

Structural and Mutational Analysis of Functional Differentiation between Synaptotagmins-1 and -7

por Xue, Mingshan, Craig, Timothy K., Shin, Ok-Ho, Li, Liyi, Brautigam, Chad A., Tomchick, Diana R., Südhof, Thomas C., Rosenmund, Christian, Rizo, Josep
Publicado 2010

Mechanistic insights into neurotransmitter release and presynaptic plasticity from the crystal structure of Munc13-1 C(1)C(2)BMUN

por Xu, Junjie, Camacho, Marcial, Xu, Yibin, Esser, Victoria, Liu, Xiaoxia, Trimbuch, Thorsten, Pan, Yun-Zu, Ma, Cong, Tomchick, Diana R, Rosenmund, Christian, Rizo, Josep
Publicado 2017

Importin-9 wraps around the H2A-H2B core to act as nuclear importer and histone chaperone

por Padavannil, Abhilash, Sarkar, Prithwijit, Kim, Seung Joong, Cagatay, Tolga, Jiou, Jenny, Brautigam, Chad A, Tomchick, Diana R, Sali, Andrej, D'Arcy, Sheena, Chook, Yuh Min
Publicado 2019

Munc13 C(2)B-Domain – an Activity-Dependent Ca(2+)-Regulator of Synaptic Exocytosis

por Shin, Ok-Ho, Lu, Jun, Rhee, Jeong-Seop, Tomchick, Diana R., Pang, Zhiping P., Wojcik, Sonja, Camacho-Perez, Marcial, Brose, Nils, Machius, Mischa, Rizo, Josep, Rosenmund, Christian, Südhof, Thomas C.
Publicado 2010

Repurposed dihydroorotate dehydrogenase inhibitors with efficacy against drug-resistant Acinetobacter baumannii

por Russo, Thomas A., Umland, Timothy C., Deng, Xiaoyi, El Mazouni, Farah, Kokkonda, Sreekanth, Olson, Ruth, Carlino-MacDonald, Ulrike, Beanan, Janet, Alvarado, Cassandra L., Tomchick, Diana R., Hutson, Alan, Chen, Hong, Posner, Bruce, Rathod, Pradipsinh K., Charman, Susan A., Phillips, Margaret A.
Publicado 2022