Metabolism, Excretion, and Pharmacokinetics of [(14)C]‐Cefiderocol (S‐649266), a Siderophore Cephalosporin, in Healthy Subjects Following Intravenous Administration

por Miyazaki, Shiro, Katsube, Takayuki, Shen, Helen, Tomek, Charles, Narukawa, Yukitoshi
Publicado 2019

A Phase 1 Study to Evaluate the Drug Interaction Between Islatravir (MK-8591) and Doravirine in Adults Without HIV

por Matthews, Randolph P., Jackson Rudd, Deanne, Fillgrove, Kerry L., Zhang, Saijuan, Tomek, Charles, Stoch, S. Aubrey, Iwamoto, Marian
Publicado 2021

Fluoride Pharmacokinetics in Urine and Plasma Following Multiple Doses of MK‐8507, an Investigational, Oral, Once‐Weekly Nonnucleoside Reverse Transcriptase Inhibitor

por Gillespie, Gillian, Jackson Rudd, Deanne, Zhang, Saijuan, Schaeffer, Andrea, Tomek, Charles, Larson, Patrick, Stoch, S. Aubrey, Iwamoto, Marian
Publicado 2021

A Phase 1 Trial to Evaluate the Relationship Between Fluoride Intake and Urinary Fluoride Excretion in Healthy Participants

por Gillespie, Gillian, Jackson Rudd, Deanne, Zhang, Saijuan, Schaeffer, Andrea, Tomek, Charles, Larson, Patrick, Stoch, S. Aubrey, Iwamoto, Marian
Publicado 2021

Pharmacokinetic and Safety Profile of the Novel HIV Nonnucleoside Reverse Transcriptase Inhibitor MK-8507 in Adults without HIV

por Ankrom, Wendy, Jackson Rudd, Deanne, Schaeffer, Andrea, Panebianco, Deborah, Friedman, Evan J., Tomek, Charles, Stoch, S. Aubrey, Iwamoto, Marian
Publicado 2021

Characterization of the absorption, metabolism, excretion, and mass balance of gefapixant in humans

por Nussbaum, Jesse C., Hussain, Azher, Ma, Bennett, Min, K. Chris, Chen, Qing, Tomek, Charles, Iwamoto, Marian, Stoch, S. Aubrey
Publicado 2022

546. No Difference in MK-8591 and Doravirine Pharmacokinetics After Co-Administration

por Matthews, Randolph, Rudd, Deanne, Fillgrove, Kerry, Fox-Bosetti, Sabrina, Levine, Vanessa, Zhang, Sandra, Tomek, Charles, Stoch, Aubrey, Iwamoto, Marian
Publicado 2018

A large multicentre, randomized, double‐blind, cross‐over study in healthy volunteers to compare pharmacokinetics, pharmacodynamics and safety of a pegfilgrastim biosimilar with it...

por Bellon, Anne, Wang, Jessie, Skerjanec, Andrej, Velinova, Maria, Dickerson, Daniel, Sabet, Ahad, Ngo, Ly, O'Reilly, Terry, Tomek, Charles, Schussler, Steven, Schier‐Mumzhiu, Stefanie, Gattu, Sreekanth, Koch, Sven D., Schelcher, Celine, Dobreva, Miryana, Boldea, Anca, Nakov, Roumen, Otto, Gordon P.
Publicado 2020