An unstructured proteasome inhibitor comes into focus

por Nemec, Antonia A., Tomko, Robert J.
Publicado 2023

Wiggle and Shake: Managing and Exploiting Conformational Dynamics during Proteasome Biogenesis

por Betancourt, Daniel, Lawal, Tomiwa, Tomko, Robert J.
Publicado 2023

Proteasome subunit α1 overexpression preferentially drives canonical proteasome biogenesis and enhances stress tolerance in yeast

por Howell, Lauren A., Peterson, Anna K., Tomko, Robert J.
Publicado 2019

The anaphase-promoting complex regulates the degradation of the inner nuclear membrane protein Mps3

por Koch, Bailey A., Jin, Hui, Tomko, Robert J., Yu, Hong-Guo
Publicado 2019

Assembly chaperone Nas6 selectively destabilizes 26S proteasomes with defective regulatory particle-core particle interfaces

por Warnock, Jennifer L., Jobin, Gabriel W., Kumar, Sandhya, Tomko, Robert J.
Publicado 2023

An Allosteric Interaction Network Promotes Conformation State-Dependent Eviction of the Nas6 Assembly Chaperone from Nascent 26S Proteasomes

por Nemec, Antonia A., Peterson, Anna K., Warnock, Jennifer L., Reed, Randi G., Tomko, Robert J.
Publicado 2019

A Single α Helix Drives Extensive Remodeling of the Proteasome Lid and Completion of Regulatory Particle Assembly

por Tomko, Robert J., Taylor, David W., Chen, Zhuo A., Wang, Hong-Wei, Rappsilber, Juri, Hochstrasser, Mark
Publicado 2015

Proteasome Inhibition Is an Effective Treatment Strategy for Microsporidia Infection in Honey Bees

por Huntsman, Emily M., Cho, Rachel M., Kogan, Helen V., McNamara-Bordewick, Nora K., Tomko, Robert J., Snow, Jonathan W.
Publicado 2021

Expanded Coverage of the 26S Proteasome Conformational Landscape Reveals Mechanisms of Peptidase Gating

por Eisele, Markus R., Reed, Randi G., Rudack, Till, Schweitzer, Andreas, Beck, Florian, Nagy, Istvan, Pfeifer, Gunter, Plitzko, Jürgen M., Baumeister, Wolfgang, Tomko, Robert J., Sakata, Eri
Publicado 2018

Wake-sleep cycles are severely disrupted by diseases affecting cytoplasmic homeostasis

por Beesley, Stephen, Kim, Dae Wook, D’Alessandro, Matthew, Jin, Yuanhu, Lee, Kwangjun, Joo, Hyunjeong, Young, Yang, Tomko, Robert J., Faulkner, John, Gamsby, Joshua, Kim, Jae Kyoung, Lee, Choogon
Publicado 2020