Modelling the consequences of interactions between tumour cells.

por Tomlinson, I. P., Bodmer, W. F.
Publicado 1997

Allele loss occurs frequently at hMLH1, but rarely at hMSH2, in sporadic colorectal cancers with microsatellite instability.

por Tomlinson, I. P., Ilyas, M., Bodmer, W. F.
Publicado 1996

Mutations in Bcl10 are very rare in colorectal cancer

por Stone, J G, Rowan, A J, Tomlinson, I P M, Houlston, R S
Publicado 1999

A study of genomic instability in early preneoplastic colonic lesions

por Beggs, A D, Domingo, E, Abulafi, M, Hodgson, S V, Tomlinson, I P M
Publicado 2013

Comprehensive analysis of common mitochondrial DNA variants and colorectal cancer risk

por Webb, E, Broderick, P, Chandler, I, Lubbe, S, Penegar, S, Tomlinson, I P M, Houlston, R S
Publicado 2008

CDX2 mutations do not account for juvenile polyposis or Peutz–Jeghers syndrome and occur infrequently in sporadic colorectal cancers

por Woodford-Richens, K L, Halford, S, Rowan, A, Bevan, S, Aaltonen, L A, Wasan, H, Bicknell, D, Bodmer, W F, Houlston, R S, Tomlinson, I P M
Publicado 2001

Allele loss and mutation screen at the Peutz-Jeghers (LKB1) locus (19p13.3) in sporadic ovarian tumours

por Wang, Z-J, Churchman, M, Campbell, I G, Xu, W-H, Yan, Z-Y, McCluggage, W G, Foulkes, W D, Tomlinson, I P M
Publicado 1999

Investigation of pathogenic mechanisms in multiple colorectal adenoma patients without germline APC or MYH/MUTYH mutations

por Thirlwell, C, Howarth, K M, Segditsas, S, Guerra, G, Thomas, H J W, Phillips, R K S, Talbot, I C, Gorman, M, Novelli, M R, Sieber, O M, Tomlinson, I P M
Publicado 2007

TERC polymorphisms are associated both with susceptibility to colorectal cancer and with longer telomeres

por Jones, A M, Beggs, A D, Carvajal-Carmona, L, Farrington, S, Tenesa, A, Walker, M, Howarth, K, Ballereau, S, Hodgson, S V, Zauber, A, Bertagnolli, M, Midgley, R, Campbell, H, Kerr, D, Dunlop, M G, Tomlinson, I P M
Publicado 2011

Mutation analysis of three genes encoding novel LKB1-interacting proteins, BRG1, STRADα, and MO25α, in Peutz–Jeghers syndrome

por Alhopuro, P, Katajisto, P, Lehtonen, R, Ylisaukko-oja, S K, Näätsaari, L, Karhu, A, Westerman, A M, Wilson, J H P, de Rooij, F W M, Vogel, T, Moeslein, G, Tomlinson, I P, Aaltonen, L A, Mäkelä, T P, Launonen, V
Publicado 2005

Whole-genome sequencing of bladder cancers reveals somatic CDKN1A mutations and clinicopathological associations with mutation burden

por Cazier, J.-B., Rao, S.R., McLean, C.M., Walker, A.L., Wright, B.J., Jaeger, E.E.M., Kartsonaki, C., Marsden, L., Yau, C., Camps, C., Kaisaki, P., Taylor, J., Catto, J.W., Tomlinson, I.P.M., Kiltie, A.E., Hamdy, F.C.
Publicado 2014

Corrigendum: Whole-genome sequencing of bladder cancers reveals somatic CDKN1A mutations and clinicopathological associations with mutation burden

por Cazier, J. -B., Rao, S. R., McLean, C. M., Walker, A. K., Wright, B. J., Jaeger, E. E. M., Kartsonaki, C., Marsden, L., Yau, C., Camps, C., Kaisaki, P., Taylor, J., Catto, J. W., Tomlinson, I. P. M., Kiltie, A. E., Hamdy, F. C.
Publicado 2014

Replication study of SNP associations for colorectal cancer in Hong Kong Chinese

por Ho, J W, Choi, S-c, Lee, Y-f, Hui, T C, Cherny, S S, Garcia-Barceló, M-M, Carvajal-Carmona, L, Liu, R, To, S-h, Yau, T-k, Chung, C C, Yau, C C, Hui, S M, Lau, P Y, Yuen, C-h, Wong, Y-w, Ho, S, Fung, S S, Tomlinson, I P, Houlston, R S, Cheng, K K, Sham, P C
Publicado 2011

Different APC genotypes in proximal and distal sporadic colorectal cancers suggest distinct WNT/β-catenin signalling thresholds for tumourigenesis

por Christie, M, Jorissen, R N, Mouradov, D, Sakthianandeswaren, A, Li, S, Day, F, Tsui, C, Lipton, L, Desai, J, Jones, I T, McLaughlin, S, Ward, R L, Hawkins, N J, Ruszkiewicz, A R, Moore, J, Burgess, A W, Busam, D, Zhao, Q, Strausberg, R L, Simpson, A J, Tomlinson, I P M, Gibbs, P, Sieber, O M
Publicado 2013

A two-phase case–control study for colorectal cancer genetic susceptibility: candidate genes from chromosomal regions 9q22 and 3q22

por Abulí, A, Fernández-Rozadilla, C, Giráldez, M D, Muñoz, J, Gonzalo, V, Bessa, X, Bujanda, L, Reñé, J M, Lanas, A, García, A M, Saló, J, Argüello, L, Vilella, À, Carreño, R, Jover, R, Xicola, R M, Llor, X, Carvajal-Carmona, L, Tomlinson, I P M, Kerr, D J, Houlston, R S, Piqué, J M, Carracedo, A, Castells, A, Andreu, M, Ruiz-Ponte, C, Castellví-Bel, S
Publicado 2011

A large-scale meta-analysis to refine colorectal cancer risk estimates associated with MUTYH variants

por Theodoratou, E, Campbell, H, Tenesa, A, Houlston, R, Webb, E, Lubbe, S, Broderick, P, Gallinger, S, Croitoru, E M, Jenkins, M A, Win, A K, Cleary, S P, Koessler, T, Pharoah, P D, Küry, S, Bézieau, S, Buecher, B, Ellis, N A, Peterlongo, P, Offit, K, Aaltonen, L A, Enholm, S, Lindblom, A, Zhou, X-L, Tomlinson, I P, Moreno, V, Blanco, I, Capellà, G, Barnetson, R, Porteous, M E, Dunlop, M G, Farrington, S M
Publicado 2010

COGENT (COlorectal cancer GENeTics): an international consortium to study the role of polymorphic variation on the risk of colorectal cancer

por Tomlinson, I P M, Dunlop, M, Campbell, H, Zanke, B, Gallinger, S, Hudson, T, Koessler, T, Pharoah, P D, Niittymäkix, I, Tuupanenx, S, Aaltonen, L A, Hemminki, K, Lindblom, A, Försti, A, Sieber, O, Lipton, L, van Wezel, T, Morreau, H, Wijnen, J T, Devilee, P, Matsuda, K, Nakamura, Y, Castellví-Bel, S, Ruiz-Ponte, C, Castells, A, Carracedo, A, Ho, J W C, Sham, P, Hofstra, R M W, Vodicka, P, Brenner, H, Hampe, J, Schafmayer, C, Tepel, J, Schreiber, S, Völzke, H, Lerch, M M, Schmidt, C A, Buch, S, Moreno, V, Villanueva, C M, Peterlongo, P, Radice, P, Echeverry, M M, Velez, A, Carvajal-Carmona, L, Scott, R, Penegar, S, Broderick, P, Tenesa, A, Houlston, R S
Publicado 2010

COGENT (COlorectal cancer GENeTics): an international consortium to study the role of polymorphic variation on the risk of colorectal cancer

por Tomlinson, I P M, Dunlop, M, Campbell, H, Zanke, B, Gallinger, S, Hudson, T, Koessler, T, Pharoah, P D, Niittymäki, I, Tuupanen, S, Aaltonen, L A, Hemminki, K, Lindblom, A, Försti, A, Sieber, O, Lipton, L, van Wezel, T, Morreau, H, Wijnen, J T, Devilee, P, Matsuda, K, Nakamura, Y, Castellví-Bel, S, Ruiz-Ponte, C, Castells, A, Carracedo, A, Ho, J W C, Sham, P, Hofstra, R M W, Vodicka, P, Brenner, H, Hampe, J, Schafmayer, C, Tepel, J, Schreiber, S, Völzke, H, Lerch, M M, Schmidt, C A, Buch, S, Moreno, V, Villanueva, C M, Peterlongo, P, Radice, P, Echeverry, M M, Velez, A, Carvajal-Carmona, L, Scott, R, Penegar, S, Broderick, P, Tenesa, A, Houlston, R S
Publicado 2010