Crystal Structure of the FERM-SH2 Module of Human Jak2

por McNally, Randall, Toms, Angela V., Eck, Michael J.
Publicado 2016

Crystal Structure of a Complex between Amino and Carboxy Terminal Fragments of mDia1: Insights into Autoinhibition of Diaphanous-Related Formins

por Nezami, Azin, Poy, Florence, Toms, Angela, Zheng, Wei, Eck, Michael J.
Publicado 2010

Distinct USP25 and USP28 Oligomerization States Regulate Deubiquitinating Activity

por Gersch, Malte, Wagstaff, Jane L., Toms, Angela V., Graves, Bradford, Freund, Stefan M.V., Komander, David
Publicado 2019

Crystal Structure of a Coiled-Coil Domain from Human ROCK I

por Tu, Daqi, Li, Yiqun, Song, Hyun Kyu, Toms, Angela V., Gould, Christopher J., Ficarro, Scott B., Marto, Jarrod A., Goode, Bruce L., Eck, Michael J.
Publicado 2011

Structure of a pseudokinase domain switch that controls oncogenic activation of Jak kinases

por Toms, Angela V., Deshpande, Anagha, McNally, Randall, Jeong, Youngjee, Rogers, Julia M., Kim, Chae Un, Gruner, Sol M., Ficarro, Scott B., Marto, Jarrod A., Sattler, Martin, Griffin, James D., Eck, Michael J.
Publicado 2013

FT-6876, a Potent and Selective Inhibitor of CBP/p300, is Active in Preclinical Models of Androgen Receptor-Positive Breast Cancer

por Caligiuri, Maureen, Williams, Grace L., Castro, Jennifer, Battalagine, Linda, Wilker, Erik, Yao, Lili, Schiller, Shawn, Toms, Angela, Li, Ping, Pardo, Eneida, Graves, Bradford, Azofeifa, Joey, Chicas, Agustin, Herbertz, Torsten, Lai, Maria, Basken, Joel, Wood, Kenneth W., Xu, Qunli, Guichard, Sylvie M.
Publicado 2023

Structural basis for isoform-specific inhibition of human CTPS1

por Lynch, Eric M., DiMattia, Michael A., Albanese, Steven, van Zundert, Gydo C. P., Hansen, Jesse M., Quispe, Joel D., Kennedy, Madison A., Verras, Andreas, Borrelli, Kenneth, Toms, Angela V., Kaila, Neelu, Kreutter, Kevin D., McElwee, Joshua J., Kollman, Justin M.
Publicado 2021

Genetic resistance to JAK2 enzymatic inhibitors is overcome by HSP90 inhibition

por Weigert, Oliver, Lane, Andrew A., Bird, Liat, Kopp, Nadja, Chapuy, Bjoern, van Bodegom, Diederik, Toms, Angela V., Marubayashi, Sachie, Christie, Amanda L., McKeown, Michael, Paranal, Ronald M., Bradner, James E., Yoda, Akinori, Gaul, Christoph, Vangrevelinghe, Eric, Romanet, Vincent, Murakami, Masato, Tiedt, Ralph, Ebel, Nicolas, Evrot, Emeline, De Pover, Alain, Régnier, Catherine H., Erdmann, Dirk, Hofmann, Francesco, Eck, Michael J., Sallan, Stephen E., Levine, Ross L., Kung, Andrew L., Baffert, Fabienne, Radimerski, Thomas, Weinstock, David M.
Publicado 2012