Identification of lipid-phosphatidylserine (PS) as the target of unbiasedly selected cancer specific peptide-peptoid hybrid PPS1

por Desai, Tanvi J., Toombs, Jason E., Minna, John D., Brekken, Rolf A., Udugamasooriya, Damith Gomika
Publicado 2016

Smac mimetic-derived augmentation of chemotherapeutic response in experimental pancreatic cancer

por Awasthi, Niranjan, Kirane, Amanda, Schwarz, Margaret A, Toombs, Jason E, Brekken, Rolf A, Schwarz, Roderich E
Publicado 2011

Cytokine Levels Correlate with Immune Cell Infiltration after Anti-VEGF Therapy in Preclinical Mouse Models of Breast Cancer

por Roland, Christina L., Lynn, Kristi D., Toombs, Jason E., Dineen, Sean P., Udugamasooriya, D. Gomika, Brekken, Rolf A.
Publicado 2009

Losartan Slows Pancreatic Tumor Progression and Extends Survival of SPARC-Null Mice by Abrogating Aberrant TGFβ Activation

por Arnold, Shanna A., Rivera, Lee B., Carbon, Juliet G., Toombs, Jason E., Chang, Chi-Lun, Bradshaw, Amy D., Brekken, Rolf A.
Publicado 2012

Tris DBA palladium is highly effective against growth and metastasis of pancreatic cancer in an orthotopic model

por Díaz, Begoña, Ostapoff, Katherine T., Toombs, Jason E., Lo, Jason, Bonner, Michael Y., Curatolo, Adam, Adsay, Volkan, Brekken, Rolf A., Arbiser, Jack L.
Publicado 2016

Human pancreatic cancer cell exosomes, but not human normal cell exosomes, act as an initiator in cell transformation

por Stefanius, Karoliina, Servage, Kelly, de Souza Santos, Marcela, Gray, Hillery Fields, Toombs, Jason E, Chimalapati, Suneeta, Kim, Min S, Malladi, Venkat S, Brekken, Rolf, Orth, Kim
Publicado 2019

r84, a Novel Therapeutic Antibody against Mouse and Human VEGF with Potent Anti-Tumor Activity and Limited Toxicity Induction

por Sullivan, Laura A., Carbon, Juliet G., Roland, Christina L., Toombs, Jason E., Nyquist-Andersen, Mari, Kavlie, Anita, Schlunegger, Kyle, Richardson, James A., Brekken, Rolf A.
Publicado 2010

Mode of action and pharmacogenomic biomarkers for exceptional responders to didemnin B

por Potts, Malia B., McMillan, Elizabeth A., Rosales, Tracy I., Kim, Hyun Seok, Ou, Yi-Hung, Toombs, Jason E., Brekken, Rolf A., Minden, Mark D., MacMillan, John B., White, Michael A.
Publicado 2015

Targeting TGFβR2‐mutant tumors exposes vulnerabilities to stromal TGFβ blockade in pancreatic cancer

por Huang, Huocong, Zhang, Yuqing, Gallegos, Valerie, Sorrelle, Noah, Zaid, Mohamed Medhat, Toombs, Jason, Du, Wenting, Wright, Steven, Hagopian, Moriah, Wang, Zhaoning, Hosein, Abdel Nasser, Sathe, Adwait Amod, Xing, Chao, Koay, Eugene J, Driscoll, Kyla E, Brekken, Rolf A
Publicado 2019

Pleiotrophin drives a prometastatic immune niche in breast cancer

por Ganguly, Debolina, Schmidt, Marcel O., Coleman, Morgan, Ngo, Tuong-Vi Cindy, Sorrelle, Noah, Dominguez, Adrian T.A., Murimwa, Gilbert Z., Toombs, Jason E., Lewis, Cheryl, Fang, Yisheng V., Valdes-Mora, Fatima, Gallego-Ortega, David, Wellstein, Anton, Brekken, Rolf A.
Publicado 2023

Extra-mitochondrial prosurvival BCL-2 proteins regulate gene transcription by inhibiting the SUFU tumor suppressor

por Wu, Xiaofeng, Zhang, Li-shu, Toombs, Jason, Kuo, Yi-Chun, Piazza, John Tyler, Tuladhar, Rubina, Barrett, Quinn, Fan, Chih-wei, Zhang, Xuewu, Walensky, Loren D., Kool, Marcel, Cheng, Steven Y., Brekken, Rolf, Opferman, Joseph T., Green, Douglas R., Moldoveanu, Tudor, Lum, Lawrence
Publicado 2017

Hemolysis-associated phosphatidylserine exposure promotes polyclonal plasmablast differentiation

por Vijay, Rahul, Guthmiller, Jenna J., Sturtz, Alexandria J., Crooks, Sequoia, Johnson, Jordan T., Li, Lei, Lan, Linda Yu-Ling, Pope, Rosemary L., Chen, Yani, Rogers, Kai J., Dutta, Nirmal, Toombs, Jason E., Wilson, Mary E., Wilson, Patrick C., Maury, Wendy, Brekken, Rolf A., Butler, Noah S.
Publicado 2021