Sequencing Strategies to Guide Decision Making in Cancer Treatment

por Topham, James T., Marra, Marco A.
Publicado 2016

Circulating tumor DNA: toward evolving the clinical paradigm of pancreatic ductal adenocarcinoma

por Topham, James T., Renouf, Daniel J., Schaeffer, David F.
Publicado 2023

Circulating Tumor DNA Identifies Diverse Landscape of Acquired Resistance to Anti–Epidermal Growth Factor Receptor Therapy in Metastatic Colorectal Cancer

por Topham, James T., O'Callaghan, Chris J., Feilotter, Harriet, Kennecke, Hagen F., Lee, Young S., Li, Weimin, Banks, Kimberly C., Quinn, Katie, Renouf, Daniel J., Jonker, Derek J., Tu, Dongsheng, Chen, Eric X., Loree, Jonathan M.
Publicado 2023

Tumor infiltrating neutrophils and gland formation predict overall survival and molecular subgroups in pancreatic ductal adenocarcinoma

por Naso, Julia R., Topham, James T., Karasinska, Joanna M., Lee, Michael K.C., Kalloger, Steve E., Wong, Hui‐li, Nelson, Jessica, Moore, Richard A., Mungall, Andrew J., Jones, Steven J.M., Laskin, Janessa, Marra, Marco A., Renouf, Daniel J., Schaeffer, David F.
Publicado 2020

Optimizing the number of variants tracked to follow disease burden with circulating tumor DNA assays in metastatic colorectal cancer

por Boutin, Mélina, Topham, James T., Feilotter, Harriet, Kennecke, Hagen F., Couture, Félix, Harb, Mohammed, Kavan, Peter, Berry, Scott, Lim, Howard J., Goffin, John R., Ahmad, Chaudhary, Lott, Anthony, Renouf, Daniel J., Jonker, Derek J., Tu, Dongsheng, O’Callaghan, Chris J., Chen, Eric X., Loree, Jonathan M.
Publicado 2023

Homologous recombination deficiency signatures in gastrointestinal and thoracic cancers correlate with platinum therapy duration

por Tsang, Erica S., Csizmok, Veronika, Williamson, Laura M., Pleasance, Erin, Topham, James T., Karasinska, Joanna M., Titmuss, Emma, Schrader, Intan, Yip, Stephen, Tessier-Cloutier, Basile, Mungall, Karen, Ng, Tony, Sun, Sophie, Lim, Howard J., Loree, Jonathan M., Laskin, Janessa, Marra, Marco A., Jones, Steven J. M., Schaeffer, David F., Renouf, Daniel J.
Publicado 2023

MicroRNA Expression-Based Model Indicates Event-Free Survival in Pediatric Acute Myeloid Leukemia

por Lim, Emilia L., Trinh, Diane L., Ries, Rhonda E., Wang, Jim, Gerbing, Robert B., Ma, Yussanne, Topham, James, Hughes, Maya, Pleasance, Erin, Mungall, Andrew J., Moore, Richard, Zhao, Yongjun, Aplenc, Richard, Sung, Lillian, Kolb, E. Anders, Gamis, Alan, Smith, Malcolm, Gerhard, Daniela S., Alonzo, Todd A., Meshinchi, Soheil, Marra, Marco A.
Publicado 2017

The CCTG PA.7 phase II trial of gemcitabine and nab-paclitaxel with or without durvalumab and tremelimumab as initial therapy in metastatic pancreatic ductal adenocarcinoma

por Renouf, Daniel J., Loree, Jonathan M., Knox, Jennifer J., Topham, James T., Kavan, Petr, Jonker, Derek, Welch, Stephen, Couture, Felix, Lemay, Frederic, Tehfe, Mustapha, Harb, Mohammed, Aucoin, Nathalie, Ko, Yoo-Joung, Tang, Patricia A., Ramjeesingh, Ravi, Meyers, Brandon M., Kim, Christina A., Du, Pan, Jia, Shidong, Schaeffer, David F., Gill, Sharlene, Tu, Dongsheng, O’Callaghan, Chris J
Publicado 2022

Identification and Analyses of Extra-Cranial and Cranial Rhabdoid Tumor Molecular Subgroups Reveal Tumors with Cytotoxic T Cell Infiltration

por Chun, Hye-Jung E., Johann, Pascal D., Milne, Katy, Zapatka, Marc, Buellesbach, Annette, Ishaque, Naveed, Iskar, Murat, Erkek, Serap, Wei, Lisa, Tessier-Cloutier, Basile, Lever, Jake, Titmuss, Emma, Topham, James T., Bowlby, Reanne, Chuah, Eric, Mungall, Karen L., Ma, Yussanne, Mungall, Andrew J., Moore, Richard A., Taylor, Michael D., Gerhard, Daniela S., Jones, Steven J.M., Korshunov, Andrey, Gessler, Manfred, Kerl, Kornelius, Hasselblatt, Martin, Frühwald, Michael C., Perlman, Elizabeth J., Nelson, Brad H., Pfister, Stefan M., Marra, Marco A., Kool, Marcel
Publicado 2019

Integrative analysis of KRAS wildtype metastatic pancreatic ductal adenocarcinoma reveals mutation and expression-based similarities to cholangiocarcinoma

por Topham, James T., Tsang, Erica S., Karasinska, Joanna M., Metcalfe, Andrew, Ali, Hassan, Kalloger, Steve E., Csizmok, Veronika, Williamson, Laura M., Titmuss, Emma, Nielsen, Karina, Negri, Gian Luca, Spencer Miko, Sandra E., Jang, Gun Ho, Denroche, Robert E., Wong, Hui-li, O’Kane, Grainne M., Moore, Richard A., Mungall, Andrew J., Loree, Jonathan M., Notta, Faiyaz, Wilson, Julie M., Bathe, Oliver F., Tang, Patricia A., Goodwin, Rachel, Morin, Gregg B., Knox, Jennifer J., Gallinger, Steven, Laskin, Janessa, Marra, Marco A., Jones, Steven J. M., Schaeffer, David F., Renouf, Daniel J.
Publicado 2022