Molecular Dynamics-Derived Pharmacophore Model Explaining the Nonselective Aspect of K(V)10.1 Pore Blockers

por Toplak, Žan, Merzel, Franci, Pardo, Luis A., Peterlin Mašič, Lucija, Tomašič, Tihomir
Publicado 2021

Efficient Synthesis of Hydroxy-Substituted 2-Aminobenzo[d]thiazole-6-carboxylic Acid Derivatives as New Building Blocks in Drug Discovery

por Durcik, Martina, Toplak, Žan, Zidar, Nace, Ilaš, Janez, Zega, Anamarija, Kikelj, Danijel, Mašič, Lucija Peterlin, Tomašič, Tihomir
Publicado 2020

Discovery of K(V)1.3 ion channel inhibitors: Medicinal chemistry approaches and challenges

por Gubič, Špela, Hendrickx, Louise A., Toplak, Žan, Sterle, Maša, Peigneur, Steve, Tomašič, Tihomir, Pardo, Luis A., Tytgat, Jan, Zega, Anamarija, Mašič, Lucija P.
Publicado 2021

New Diarylamine K(V)10.1 Inhibitors and Their Anticancer Potential

por Gubič, Špela, Toplak, Žan, Shi, Xiaoyi, Dernovšek, Jaka, Hendrickx, Louise Antonia, Pinheiro-Junior, Ernesto Lopes, Peigneur, Steve, Tytgat, Jan, Pardo, Luis A., Peterlin Mašič, Lucija, Tomašič, Tihomir
Publicado 2022

3D Pharmacophore-Based Discovery of Novel K(V)10.1 Inhibitors with Antiproliferative Activity

por Toplak, Žan, Hendrickx, Louise Antonia, Gubič, Špela, Možina, Štefan, Žegura, Bojana, Štern, Alja, Novak, Matjaž, Shi, Xiaoyi, Peigneur, Steve, Tytgat, Jan, Tomašič, Tihomir, Pardo, Luis A., Mašič, Lucija Peterlin
Publicado 2021

Correction: Gubič et al. Design of New Potent and Selective Thiophene-Based K(V)1.3 Inhibitors and Their Potential for Anticancer Activity. Cancers 2022, 14, 2595

por Gubič, Špela, Hendrickx, Louise Antonia, Shi, Xiaoyi, Toplak, Žan, Možina, Štefan, Theemsche, Kenny M. Van, Pinheiro-Junior, Ernesto Lopes, Peigneur, Steve, Labro, Alain J., Pardo, Luis A., Tytgat, Jan, Tomašič, Tihomir, Peterlin Mašič, Lucija
Publicado 2023

Design of New Potent and Selective Thiophene-Based K(V)1.3 Inhibitors and Their Potential for Anticancer Activity

por Gubič, Špela, Hendrickx, Louise Antonia, Shi, Xiaoyi, Toplak, Žan, Možina, Štefan, Theemsche, Kenny M. Van, Pinheiro-Junior, Ernesto Lopes, Peigneur, Steve, Labro, Alain J., Pardo, Luis A., Tytgat, Jan, Tomašič, Tihomir, Mašič, Lucija Peterlin
Publicado 2022

Structure-Function Studies of Sponge-Derived Compounds on the Cardiac Ca(V)3.1 Channel

por Depuydt, Anne-Sophie, Patel, Piyush A., Toplak, Žan, Bhat, Chinmaya, Voráčová, Manuela, Eteläinen, Irene, Vitulano, Fiammetta, Bruun, Tanja, Lempinen, Antti, Hribernik, Nives, Mäki-Lohiluoma, Eero, Hendrickx, Louise, Pinheiro-Junior, Ernesto Lopes, Tomašič, Tihomir, Mašič, Lucija Peterlin, Yli-Kauhaluoma, Jari, Kiuru, Paula, Tytgat, Jan, Peigneur, Steve
Publicado 2023

New Dual Inhibitors of Bacterial Topoisomerases with Broad-Spectrum Antibacterial Activity and In Vivo Efficacy against Vancomycin-Intermediate Staphylococcus aureus

por Durcik, Martina, Cotman, Andrej Emanuel, Toplak, Žan, Možina, Štefan, Skok, Žiga, Szili, Petra Eva, Czikkely, Márton, Maharramov, Elvin, Vu, Thu Hien, Piras, Maria Vittoria, Zidar, Nace, Ilaš, Janez, Zega, Anamarija, Trontelj, Jurij, Pardo, Luis A., Hughes, Diarmaid, Huseby, Douglas, Berruga-Fernández, Tália, Cao, Sha, Simoff, Ivailo, Svensson, Richard, Korol, Sergiy V., Jin, Zhe, Vicente, Francisca, Ramos, Maria C., Mundy, Julia E. A., Maxwell, Anthony, Stevenson, Clare E. M., Lawson, David M., Glinghammar, Björn, Sjöström, Eva, Bohlin, Martin, Oreskär, Joanna, Alvér, Sofie, Janssen, Guido V., Sterk, Geert Jan, Kikelj, Danijel, Pal, Csaba, Tomašič, Tihomir, Peterlin Mašič, Lucija
Publicado 2023