Label-Free Optical Detection of Pathogenic Bacteria and Fungi at Extremely Low Cell Densities for Rapid Antibiotic Susceptibility Testing

por Farid, Michael, Rodrigues, Marinelle, England, Robert, Toprak, Erdal
Publicado 2022

Rapid ultrasensitive detection platform for antimicrobial susceptibility testing

por Cansizoglu, Mehmet F., Tamer, Yusuf Talha, Farid, Michael, Koh, Andrew Y., Toprak, Erdal
Publicado 2019

Quantifying the Determinants of Evolutionary Dynamics Leading to Drug Resistance

por Chevereau, Guillaume, Dravecká, Marta, Batur, Tugce, Guvenek, Aysegul, Ayhan, Dilay Hazal, Toprak, Erdal, Bollenbach, Tobias
Publicado 2015

Kinetic Barrier to Enzyme Inhibition Is Manipulated by Dynamical Local Interactions in E. coli DHFR

por Cetin, Ebru, Guclu, Tandac F., Kantarcioglu, Isik, Gaszek, Ilona K., Toprak, Erdal, Atilgan, Ali Rana, Dedeoglu, Burcu, Atilgan, Canan
Publicado 2023

The Antibiotic Efflux Protein TolC Is a Highly Evolvable Target under Colicin E1 or TLS Phage Selection

por Tamer, Yusuf Talha, Gaszek, Ilona, Rodrigues, Marinelle, Coskun, Fatma Sevde, Farid, Michael, Koh, Andrew Y, Russ, William, Toprak, Erdal
Publicado 2021

Sequence-Specific Targeting of Bacterial Resistance Genes Increases Antibiotic Efficacy

por Ayhan, Dilay Hazal, Tamer, Yusuf Talha, Akbar, Mohammed, Bailey, Stacey M., Wong, Michael, Daly, Seth M., Greenberg, David E., Toprak, Erdal
Publicado 2016

High-Order Epistasis in Catalytic Power of Dihydrofolate Reductase Gives Rise to a Rugged Fitness Landscape in the Presence of Trimethoprim Selection

por Tamer, Yusuf Talha, Gaszek, Ilona K, Abdizadeh, Haleh, Batur, Tugce Altinusak, Reynolds, Kimberly A, Atilgan, Ali Rana, Atilgan, Canan, Toprak, Erdal
Publicado 2019

Strength of Selection Pressure Is an Important Parameter Contributing to the Complexity of Antibiotic Resistance Evolution

por Oz, Tugce, Guvenek, Aysegul, Yildiz, Sadik, Karaboga, Enes, Tamer, Yusuf Talha, Mumcuyan, Nirva, Ozan, Vedat Burak, Senturk, Gizem Hazal, Cokol, Murat, Yeh, Pamela, Toprak, Erdal
Publicado 2014

Mechanical slowing-down of cytoplasmic diffusion allows in vivo counting of proteins in individual cells

por Okumus, Burak, Landgraf, Dirk, Lai, Ghee Chuan, Bakhsi, Somenath, Arias-Castro, Juan Carlos, Yildiz, Sadik, Huh, Dann, Fernandez-Lopez, Raul, Peterson, Celeste N., Toprak, Erdal, El Karoui, Meriem, Paulsson, Johan
Publicado 2016

Corrigendum: Mechanical slowing-down of cytoplasmic diffusion allows in vivo counting of proteins in individual cells

por Okumus, Burak, Landgraf, Dirk, Lai, Ghee Chuan, Bakshi, Somenath, Arias-Castro, Juan Carlos, Yildiz, Sadik, Huh, Dann, Fernandez-Lopez, Raul, Peterson, Celeste N., Toprak, Erdal, El Karoui, Meriem, Paulsson, Johan
Publicado 2016

Non-antibiotic Small-Molecule Regulation of DHFR-Based Destabilizing Domains In Vivo

por Peng, Hui, Chau, Viet Q., Phetsang, Wanida, Sebastian, Rebecca M., Stone, M. Rhia L., Datta, Shyamtanu, Renwick, Marian, Tamer, Yusuf T., Toprak, Erdal, Koh, Andrew Y., Blaskovich, Mark A.T., Hulleman, John D.
Publicado 2019

A trimethoprim derivative impedes antibiotic resistance evolution

por Manna, Madhu Sudan, Tamer, Yusuf Talha, Gaszek, Ilona, Poulides, Nicole, Ahmed, Ayesha, Wang, Xiaoyu, Toprak, Furkan C. R., Woodard, DaNae R., Koh, Andrew Y., Williams, Noelle S., Borek, Dominika, Atilgan, Ali Rana, Hulleman, John D., Atilgan, Canan, Tambar, Uttam, Toprak, Erdal
Publicado 2021