Assemblages: Functional units formed by cellular phase separation

por Toretsky, Jeffrey A., Wright, Peter E.
Publicado 2014

YK-4-279 Inhibits ERG and ETV1 Mediated Prostate Cancer Cell Invasion

por Rahim, Said, Beauchamp, Elspeth M., Kong, Yali, Brown, Milton L., Toretsky, Jeffrey A., Üren, Aykut
Publicado 2011

Factor VII deficiency and developmental abnormalities in a patient with partial monosomy of 13q and trisomy of 16p: case report and review of the literature

por Brooks, Brian P, Meck, Jeanne M, Haddad, Bassem R, Bendavid, Claude, Blain, Delphine, Toretsky, Jeffrey A
Publicado 2006

Acetylation Increases EWS-FLI1 DNA Binding and Transcriptional Activity

por Schlottmann, Silke, Erkizan, Hayriye V., Barber-Rotenberg, Julie S., Knights, Chad, Cheema, Amrita, Üren, Aykut, Avantaggiati, Maria L., Toretsky, Jeffrey A.
Publicado 2012

Comprehensive profiling of mRNA splicing indicates that GC content signals altered cassette exon inclusion in Ewing sarcoma

por Graham, Garrett T, Selvanathan, Saravana P, Zöllner, Stefan K, Stahl, Emily, Shlien, Adam, Caplen, Natasha J, Üren, Aykut, Toretsky, Jeffrey A
Publicado 2022

Clofarabine induces ERK/MSK/CREB activation through inhibiting CD99 on Ewing sarcoma cells

por Sevim, Handan, Çelik, Haydar, Düşünceli, Levent, Ceyhan, Ceyda S., Molotkova, Anna, Nakazawa, Kay, Graham, Garrett T., Petro, Jeffrey R., Toretsky, Jeffrey A., Üren, Aykut
Publicado 2021

High ALDH Activity Identifies Chemotherapy-Resistant Ewing's Sarcoma Stem Cells That Retain Sensitivity to EWS-FLI1 Inhibition

por Awad, Ola, Yustein, Jason T., Shah, Preeti, Gul, Naheed, Katuri, Varalakshmi, O'Neill, Alison, Kong, Yali, Brown, Milton L., Toretsky, Jeffrey A., Loeb, David M.
Publicado 2010

An Intrinsically Disordered Region of the Acetyltransferase p300 with Similarity to Prion-Like Domains Plays a Role in Aggregation

por Kirilyuk, Alexander, Shimoji, Mika, Catania, Jason, Sahu, Geetaram, Pattabiraman, Nagarajan, Giordano, Antonio, Albanese, Christopher, Mocchetti, Italo, Toretsky, Jeffrey A., Uversky, Vladimir N., Avantaggiati, Maria Laura
Publicado 2012

Pharmacokinetic modeling optimizes inhibition of the ‘undruggable’ EWS-FLI1 transcription factor in Ewing Sarcoma

por Hong, Sung-Hyeok, Youbi, Sarah. E., Hong, S. Peter, Kallakury, Bhaskar, Monroe, Phillip, Erkizan, Hayriye V, Barber-Rotenberg, Julie S., Houghton, Peter, Üren, Aykut, Toretsky, Jeffrey A.
Publicado 2013

Ezrin Enhances EGFR Signaling and Modulates Erlotinib Sensitivity in Non–Small Cell Lung Cancer Cells()

por Saygideğer-Kont, Yasemin, Minas, Tsion Zewdu, Jones, Hayden, Hour, Sarah, Çelik, Haydar, Temel, Idil, Han, Jenny, Atabey, Nese, Erkizan, Hayriye Verda, Toretsky, Jeffrey A., Üren, Aykut
Publicado 2016

Beta-Catenin Accelerates Human Papilloma Virus Type-16 Mediated Cervical Carcinogenesis in Transgenic Mice

por Bulut, Gülay, Fallen, Shannon, Beauchamp, Elspeth M., Drebing, Lauren E., Sun, Junfeng, Berry, Deborah L., Kallakury, Bhaskar, Crum, Christopher P., Toretsky, Jeffrey A., Schlegel, Richard, Üren, Aykut
Publicado 2011

Small molecule selected to disrupt oncogenic protein EWS-FLI1 interaction with RNA Helicase A inhibits Ewing's Sarcoma

por Erkizan, Hayriye V., Kong, Yali, Merchant, Melinda, Schlottmann, Silke, Barber-Rotenberg, Julie S., Abaan, Ogan D., Chou, Tsu-hang, Dakshanamurthy, Sivanesan, Brown, Milton L., Üren, Aykut, Toretsky, Jeffrey A.
Publicado 2009

RNA helicase A activity is inhibited by oncogenic transcription factor EWS-FLI1

por Erkizan, Hayriye Verda, Schneider, Jeffrey A., Sajwan, Kamal, Graham, Garrett T., Griffin, Brittany, Chasovskikh, Sergey, Youbi, Sarah E., Kallarakal, Abraham, Chruszcz, Maksymilian, Padmanabhan, Radhakrishnan, Casey, John L., Üren, Aykut, Toretsky, Jeffrey A.
Publicado 2015

EWS–FLI1 modulated alternative splicing of ARID1A reveals novel oncogenic function through the BAF complex

por Selvanathan, Saravana P, Graham, Garrett T, Grego, Alexander R, Baker, Tabari M, Hogg, J Robert, Simpson, Mark, Batish, Mona, Crompton, Brian, Stegmaier, Kimberly, Tomazou, Eleni M, Kovar, Heinrich, Üren, Aykut, Toretsky, Jeffrey A
Publicado 2019

A Small Molecule Inhibitor of ETV1, YK-4-279, Prevents Prostate Cancer Growth and Metastasis in a Mouse Xenograft Model

por Rahim, Said, Minas, Tsion, Hong, Sung-Hyeok, Justvig, Sarah, Çelik, Haydar, Kont, Yasemin Saygideger, Han, Jenny, Kallarakal, Abraham T., Kong, Yali, Rudek, Michelle A., Brown, Milton L., Kallakury, Bhaskar, Toretsky, Jeffrey A., Üren, Aykut
Publicado 2014

Osteosarcoma enters a post genomic era with in silico opportunities: Generation of the High Dimensional Database for facilitating sarcoma biology research: A report from the Childr...

por Glover, Jason, Man, Tsz-Kwong, Barkauskas, Donald A., Hall, David, Tello, Tanya, Sullivan, Mary Beth, Gorlick, Richard, Janeway, Katherine, Grier, Holcombe, Lau, Ching, Toretsky, Jeffrey A., Borinstein, Scott C., Khanna, Chand, Fan, Timothy M.
Publicado 2017

Neuropeptide Y and its Y2 Receptor – Potential Targets in Neuroblastoma Therapy

por Lu, Congyi, Everhart, Lindsay, Tilan, Jason, Kuo, Lydia, Sun, Chen-Chih J., Munivenkatappa, Raghava B, Jönsson-Rylander, Ann-Cathrine, Sun, Junfeng, Kuan-Celarier, Anna, Li, Lijun, Abe, Ken, Zukowska, Zofia, Toretsky, Jeffrey A., Kitlinska, Joanna
Publicado 2010

Piperacetazine Directly Binds to the PAX3::FOXO1 Fusion Protein and Inhibits Its Transcriptional Activity

por Nakazawa, Kay, Shaw, Taryn, Song, Young K., Kouassi-Brou, Marilyn, Molotkova, Anna, Tiwari, Purushottam B., Chou, Hsien-Chao, Wen, Xinyu, Wei, Jun S., Deniz, Emre, Toretsky, Jeffrey A., Keller, Charles, Barr, Frederic G., Khan, Javed, Üren, Aykut
Publicado 2023

Widespread hypertranscription in aggressive human cancers

por Zatzman, Matthew, Fuligni, Fabio, Ripsman, Ryan, Suwal, Tannu, Comitani, Federico, Edward, Lisa-Monique, Denroche, Rob, Jang, Gun Ho, Notta, Faiyaz, Gallinger, Steven, Selvanathan, Saravana P., Toretsky, Jeffrey A., Hellmann, Matthew D., Tabori, Uri, Huang, Annie, Shlien, Adam
Publicado 2022

High neuropeptide Y release associates with Ewing sarcoma bone dissemination - in vivo model of site-specific metastases

por Hong, Sung-Hyeok, Tilan, Jason U., Galli, Susana, Izycka-Swieszewska, Ewa, Polk, Taylor, Horton, Meredith, Mahajan, Akanksha, Christian, David, Jenkins, Shari, Acree, Rachel, Connors, Katherine, Ledo, Phuong, Lu, Congyi, Lee, Yi-Chien, Rodriguez, Olga, Toretsky, Jeffrey A., Albanese, Chris, Kitlinska, Joanna
Publicado 2015