Identification of Novel Smoothened Ligands Using Structure-Based Docking

por Lacroix, Celine, Fish, Inbar, Torosyan, Hayarpi, Parathaman, Pranavan, Irwin, John J., Shoichet, Brian K., Angers, Stephane
Publicado 2016

Structural insights into regulation of the PEAK3 pseudokinase scaffold by 14-3-3

por Torosyan, Hayarpi, Paul, Michael D., Forget, Antoine, Lo, Megan, Diwanji, Devan, Pawłowski, Krzysztof, Krogan, Nevan J., Jura, Natalia, Verba, Kliment A.
Publicado 2023

CNPY4 inhibits the Hedgehog pathway by modulating membrane sterol lipids

por Lo, Megan, Sharir, Amnon, Paul, Michael D., Torosyan, Hayarpi, Agnew, Christopher, Li, Amy, Neben, Cynthia, Marangoni, Pauline, Xu, Libin, Raleigh, David R., Jura, Natalia, Klein, Ophir D.
Publicado 2022

Structure-based discovery of selective positive allosteric modulators of antagonists for the M(2) muscarinic acetylcholine receptor

por Korczynska, Magdalena, Clark, Mary J., Valant, Celine, Xu, Jun, Moo, Ee Von, Albold, Sabine, Weiss, Dahlia R., Torosyan, Hayarpi, Huang, Weijiao, Kruse, Andrew C., Lyda, Brent R., May, Lauren T., Baltos, Jo-Anne, Sexton, Patrick M., Kobilka, Brian K., Christopoulos, Arthur, Shoichet, Brian K., Sunahara, Roger K.
Publicado 2018