Nuclease-dead S. aureus Cas9 downregulates alpha-synuclein and reduces mtDNA damage and oxidative stress levels in patient-derived stem cell model of Parkinson’s disease

por Sastre, Danuta, Zafar, Faria, Torres, C. Alejandra Morato, Piper, Desiree, Kirik, Deniz, Sanders, Laurie H., Qi, Stanley, Schüle, Birgitt
Publicado 2023

Inactive S. aureus Cas9 downregulates alpha-synuclein and reduces mtDNA damage and oxidative stress levels in human stem cell model of Parkinson’s disease

por Sastre, Danuta, Zafar, Faria, Torres, C. Alejandra Morato, Piper, Desiree, Kirik, Deniz, Sanders, Laurie H., Qi, L. Stanley, Schüle, Birgitt
Publicado 2023