Therapeutic Inhibition of the Complement System in Diseases of the Central Nervous System

por Carpanini, Sarah M., Torvell, Megan, Morgan, Bryan Paul
Publicado 2019

A single systemic inflammatory insult causes acute motor deficits and accelerates disease progression in a mouse model of human tauopathy

por Torvell, Megan, Hampton, David W., Connick, Peter, MacLullich, Alasdair M.J., Cunningham, Colm, Chandran, Siddharthan
Publicado 2019

Genetic Insights into the Impact of Complement in Alzheimer’s Disease

por Torvell, Megan, Carpanini, Sarah M., Daskoulidou, Nikoleta, Byrne, Robert A. J., Sims, Rebecca, Morgan, B. Paul
Publicado 2021

Complement factor I deficiency: A potentially treatable cause of fulminant cerebral inflammation

por Altmann, Tom, Torvell, Megan, Owens, Stephen, Mitra, Dipayan, Sheerin, Neil S., Morgan, B. Paul, Kavanagh, David, Forsyth, Rob
Publicado 2020

HspB5 Activates a Neuroprotective Glial Cell Response in Experimental Tauopathy

por Hampton, David W., Amor, Sandra, Story, David, Torvell, Megan, Bsibsi, Malika, van Noort, Johannes M., Chandran, Siddarthan
Publicado 2020

The Impact of Complement Genes on the Risk of Late-Onset Alzheimer’s Disease

por Carpanini, Sarah M., Harwood, Janet C., Baker, Emily, Torvell, Megan, Sims, Rebecca, Williams, Julie, Morgan, B. Paul
Publicado 2021

Novel Monoclonal Antibodies Against Mouse C1q: Characterisation and Development of a Quantitative ELISA for Mouse C1q

por Byrne, Robert A. J., Torvell, Megan, Daskoulidou, Nikoleta, Fathalla, Dina, Kokkali, Eirini, Carpanini, Sarah M., Morgan, B. Paul
Publicado 2021

Dendritic spine loss in epileptogenic Type II focal cortical dysplasia: Role of enhanced classical complement pathway activation

por Rossini, Laura, De Santis, Dalia, Cecchini, Erica, Cagnoli, Cinzia, Maderna, Emanuela, Cartelli, Daniele, Morgan, Bryan Paul, Torvell, Megan, Spreafico, Roberto, di Giacomo, Roberta, Tassi, Laura, de Curtis, Marco, Garbelli, Rita
Publicado 2022

Terminal complement pathway activation drives synaptic loss in Alzheimer’s disease models

por Carpanini, Sarah M., Torvell, Megan, Bevan, Ryan J., Byrne, Robert A. J., Daskoulidou, Nikoleta, Saito, Takashi, Saido, Takaomi C., Taylor, Philip R., Hughes, Timothy R., Zelek, Wioleta M., Morgan, B. Paul
Publicado 2022

Neurons and neuronal activity control gene expression in astrocytes to regulate their development and metabolism

por Hasel, Philip, Dando, Owen, Jiwaji, Zoeb, Baxter, Paul, Todd, Alison C., Heron, Samuel, Márkus, Nóra M., McQueen, Jamie, Hampton, David W., Torvell, Megan, Tiwari, Sachin S., McKay, Sean, Eraso-Pichot, Abel, Zorzano, Antonio, Masgrau, Roser, Galea, Elena, Chandran, Siddharthan, Wyllie, David J. A., Simpson, T. Ian, Hardingham, Giles E.
Publicado 2017

Author Correction: Neurons and neuronal activity control gene expression in astrocytes to regulate their development and metabolism

por Hasel, Philip, Dando, Owen, Jiwaji, Zoeb, Baxter, Paul, Todd, Alison C., Heron, Samuel, Márkus, Nóra M., McQueen, Jamie, Hampton, David W., Torvell, Megan, Tiwari, Sachin S., McKay, Sean, Eraso-Pichot, Abel, Zorzano, Antonio, Masgrau, Roser, Galea, Elena, Chandran, Siddharthan, Wyllie, David J. A., Simpson, T. Ian, Hardingham, Giles E.
Publicado 2018

Reactive astrocytes acquire neuroprotective as well as deleterious signatures in response to Tau and Aß pathology

por Jiwaji, Zoeb, Tiwari, Sachin S., Avilés-Reyes, Rolando X., Hooley, Monique, Hampton, David, Torvell, Megan, Johnson, Delinda A., McQueen, Jamie, Baxter, Paul, Sabari-Sankar, Kayalvizhi, Qiu, Jing, He, Xin, Fowler, Jill, Febery, James, Gregory, Jenna, Rose, Jamie, Tulloch, Jane, Loan, Jamie, Story, David, McDade, Karina, Smith, Amy M., Greer, Peta, Ball, Matthew, Kind, Peter C., Matthews, Paul M., Smith, Colin, Dando, Owen, Spires-Jones, Tara L., Johnson, Jeffrey A., Chandran, Siddharthan, Hardingham, Giles E.
Publicado 2022