A glance at post-translational modifications of human thyroglobulin: potential impact on function and pathogenesis

por Tosatto, Laura, Coscia, Francesca
Publicado 2022

Single-molecule FRET studies on alpha-synuclein oligomerization of Parkinson’s disease genetically related mutants

por Tosatto, Laura, Horrocks, Mathew H., Dear, Alexander J., Knowles, Tuomas P. J., Dalla Serra, Mauro, Cremades, Nunilo, Dobson, Christopher M., Klenerman, David
Publicado 2015

Arachidonic acid mediates the formation of abundant alpha-helical multimers of alpha-synuclein

por Iljina, Marija, Tosatto, Laura, Choi, Minee L., Sang, Jason C., Ye, Yu, Hughes, Craig D., Bryant, Clare E., Gandhi, Sonia, Klenerman, David
Publicado 2016

Increased mitophagy in the skeletal muscle of spinal and bulbar muscular atrophy patients

por Borgia, Doriana, Malena, Adriana, Spinazzi, Marco, Desbats, Maria Andrea, Salviati, Leonardo, Russell, Aaron P., Miotto, Giovanni, Tosatto, Laura, Pegoraro, Elena, Sorarù, Gianni, Pennuto, Maria, Vergani, Lodovica
Publicado 2017

Covalent α-Synuclein Dimers: Chemico-Physical and Aggregation Properties

por Pivato, Micaela, De Franceschi, Giorgia, Tosatto, Laura, Frare, Erica, Kumar, Dhruv, Aioanei, Daniel, Brucale, Marco, Tessari, Isabella, Bisaglia, Marco, Samori, Bruno, de Laureto, Patrizia Polverino, Bubacco, Luigi
Publicado 2012

Single-Molecule Characterization of the Interactions between Extracellular Chaperones and Toxic α-Synuclein Oligomers

por Whiten, Daniel R., Cox, Dezerae, Horrocks, Mathew H., Taylor, Christopher G., De, Suman, Flagmeier, Patrick, Tosatto, Laura, Kumita, Janet R., Ecroyd, Heath, Dobson, Christopher M., Klenerman, David, Wilson, Mark R.
Publicado 2018

Quantifying Co-Oligomer Formation by α-Synuclein

por Iljina, Marija, Dear, Alexander J., Garcia, Gonzalo A., De, Suman, Tosatto, Laura, Flagmeier, Patrick, Whiten, Daniel R., Michaels, Thomas C. T., Frenkel, Daan, Dobson, Christopher M., Knowles, Tuomas P. J., Klenerman, David
Publicado 2018

Multi-dimensional super-resolution imaging enables surface hydrophobicity mapping

por Bongiovanni, Marie N., Godet, Julien, Horrocks, Mathew H., Tosatto, Laura, Carr, Alexander R., Wirthensohn, David C., Ranasinghe, Rohan T., Lee, Ji-Eun, Ponjavic, Aleks, Fritz, Joelle V., Dobson, Christopher M., Klenerman, David, Lee, Steven F.
Publicado 2016

Single-Molecule Imaging of Individual Amyloid Protein Aggregates in Human Biofluids

por Horrocks, Mathew H., Lee, Steven F., Gandhi, Sonia, Magdalinou, Nadia K., Chen, Serene W., Devine, Michael J., Tosatto, Laura, Kjaergaard, Magnus, Beckwith, Joseph S., Zetterberg, Henrik, Iljina, Marija, Cremades, Nunilo, Dobson, Christopher M., Wood, Nicholas W., Klenerman, David
Publicado 2016

Huntingtin-mediated axonal transport requires arginine methylation by PRMT6

por Migazzi, Alice, Scaramuzzino, Chiara, Anderson, Eric N., Tripathy, Debasmita, Hernández, Ivó H., Grant, Rogan A., Roccuzzo, Michela, Tosatto, Laura, Virlogeux, Amandine, Zuccato, Chiara, Caricasole, Andrea, Ratovitski, Tamara, Ross, Christopher A., Pandey, Udai B., Lucas, José J., Saudou, Frédéric, Pennuto, Maria, Basso, Manuela
Publicado 2021

Antagonistic effect of cyclin-dependent kinases and a calcium-dependent phosphatase on polyglutamine-expanded androgen receptor toxic gain of function

por Piol, Diana, Tosatto, Laura, Zuccaro, Emanuela, Anderson, Eric N., Falconieri, Antonella, Polanco, Maria J., Marchioretti, Caterina, Lia, Federica, White, Joseph, Bregolin, Elisa, Minervini, Giovanni, Parodi, Sara, Salvatella, Xavier, Arrigoni, Giorgio, Ballabio, Andrea, La Spada, Albert R., Tosatto, Silvio C. E., Sambataro, Fabio, Medina, Diego L., Pandey, Udai B., Basso, Manuela, Pennuto, Maria
Publicado 2023

LSD1/PRMT6-targeting gene therapy to attenuate androgen receptor toxic gain-of-function ameliorates spinobulbar muscular atrophy phenotypes in flies and mice

por Prakasam, Ramachandran, Bonadiman, Angela, Andreotti, Roberta, Zuccaro, Emanuela, Dalfovo, Davide, Marchioretti, Caterina, Tripathy, Debasmita, Petris, Gianluca, Anderson, Eric N., Migazzi, Alice, Tosatto, Laura, Cereseto, Anna, Battaglioli, Elena, Sorarù, Gianni, Lim, Wooi Fang, Rinaldi, Carlo, Sambataro, Fabio, Pourshafie, Naemeh, Grunseich, Christopher, Romanel, Alessandro, Pandey, Udai Bhan, Contestabile, Andrea, Ronzitti, Giuseppe, Basso, Manuela, Pennuto, Maria
Publicado 2023

Pharmacological inactivation of the prion protein by targeting a folding intermediate

por Spagnolli, Giovanni, Massignan, Tania, Astolfi, Andrea, Biggi, Silvia, Rigoli, Marta, Brunelli, Paolo, Libergoli, Michela, Ianeselli, Alan, Orioli, Simone, Boldrini, Alberto, Terruzzi, Luca, Bonaldo, Valerio, Maietta, Giulia, Lorenzo, Nuria L., Fernandez, Leticia C., Codeseira, Yaiza B., Tosatto, Laura, Linsenmeier, Luise, Vignoli, Beatrice, Petris, Gianluca, Gasparotto, Dino, Pennuto, Maria, Guella, Graziano, Canossa, Marco, Altmeppen, Hermann C., Lolli, Graziano, Biressi, Stefano, Pastor, Manuel M., Requena, Jesús R., Mancini, Ines, Barreca, Maria L., Faccioli, Pietro, Biasini, Emiliano
Publicado 2021

Pathological structural conversion of α-synuclein at the mitochondria induces neuronal toxicity

por Choi, Minee L., Chappard, Alexandre, Singh, Bhanu P., Maclachlan, Catherine, Rodrigues, Margarida, Fedotova, Evgeniya I., Berezhnov, Alexey V., De, Suman, Peddie, Christopher J., Athauda, Dilan, Virdi, Gurvir S., Zhang, Weijia, Evans, James R., Wernick, Anna I., Zanjani, Zeinab Shadman, Angelova, Plamena R., Esteras, Noemi, Vinokurov, Andrey Y., Morris, Katie, Jeacock, Kiani, Tosatto, Laura, Little, Daniel, Gissen, Paul, Clarke, David J., Kunath, Tilo, Collinson, Lucy, Klenerman, David, Abramov, Andrey Y., Horrocks, Mathew H., Gandhi, Sonia
Publicado 2022

Author Correction: Pathological structural conversion of α-synuclein at the mitochondria induces neuronal toxicity

por Choi, Minee L., Chappard, Alexandre, Singh, Bhanu P., Maclachlan, Catherine, Rodrigues, Margarida, Fedotova, Evgeniya I., Berezhnov, Alexey V., De, Suman, Peddie, Christopher J., Athauda, Dilan, Virdi, Gurvir S., Zhang, Weijia, Evans, James R., Wernick, Anna I., Zanjani, Zeinab Shadman, Angelova, Plamena R., Esteras, Noemi, Vinokurov, Andrey Y., Morris, Katie, Jeacock, Kiani, Tosatto, Laura, Little, Daniel, Gissen, Paul, Clarke, David J., Kunath, Tilo, Collinson, Lucy, Klenerman, David, Abramov, Andrey Y., Horrocks, Mathew H., Gandhi, Sonia
Publicado 2022