The Metabolic Features of Osteoblasts: Implications for Multiple Myeloma (MM) Bone Disease

por Lungu, Oxana, Toscani, Denise, Burroughs-Garcia, Jessica, Giuliani, Nicola
Publicado 2023

Role of Osteocytes in Myeloma Bone Disease: Anti-sclerostin Antibody as New Therapeutic Strategy

por Toscani, Denise, Bolzoni, Marina, Ferretti, Marzia, Palumbo, Carla, Giuliani, Nicola
Publicado 2018

Mechanism of Action of Bortezomib and the New Proteasome Inhibitors on Myeloma Cells and the Bone Microenvironment: Impact on Myeloma-Induced Alterations of Bone Remodeling

por Accardi, Fabrizio, Toscani, Denise, Bolzoni, Marina, Dalla Palma, Benedetta, Aversa, Franco, Giuliani, Nicola
Publicado 2015

Metabolic features of myeloma cells in the context of bone microenvironment: Implication for the pathophysiology and clinic of myeloma bone disease

por Raimondi, Vincenzo, Toscani, Denise, Marchica, Valentina, Burroughs-Garcia, Jessica, Storti, Paola, Giuliani, Nicola
Publicado 2022

A personalized molecular approach in multiple myeloma: the possible use of RAF/RAS/MEK/ERK and BCL-2 inhibitors

por Raimondi, Vincenzo, Iannozzi, Nicolas Thomas, Burroughs-Garcìa, Jessica, Toscani, Denise, Storti, Paola, Giuliani, Nicola
Publicado 2022

Molecular Features of the Mesenchymal and Osteoblastic Cells in Multiple Myeloma

por Iannozzi, Nicolas Thomas, Marchica, Valentina, Toscani, Denise, Burroughs Garcìa, Jessica, Giuliani, Nicola, Storti, Paola
Publicado 2022

Multiple myeloma-derived exosomes are enriched of amphiregulin (AREG) and activate the epidermal growth factor pathway in the bone microenvironment leading to osteoclastogenesis

por Raimondo, Stefania, Saieva, Laura, Vicario, Emanuela, Pucci, Marzia, Toscani, Denise, Manno, Mauro, Raccosta, Samuele, Giuliani, Nicola, Alessandro, Riccardo
Publicado 2019

Novel Approaches to Improve Myeloma Cell Killing by Monoclonal Antibodies

por Storti, Paola, Costa, Federica, Marchica, Valentina, Burroughs-Garcia, Jessica, dalla Palma, Benedetta, Toscani, Denise, Eufemiese, Rosa Alba, Giuliani, Nicola
Publicado 2020

Role of 1q21 in Multiple Myeloma: From Pathogenesis to Possible Therapeutic Targets

por Burroughs Garcìa, Jessica, Eufemiese, Rosa Alba, Storti, Paola, Sammarelli, Gabriella, Craviotto, Luisa, Todaro, Giannalisa, Toscani, Denise, Marchica, Valentina, Giuliani, Nicola
Publicado 2021

New Insights into Osteogenic and Chondrogenic Differentiation of Human Bone Marrow Mesenchymal Stem Cells and Their Potential Clinical Applications for Bone Regeneration in Pediatr...

por Giuliani, Nicola, Lisignoli, Gina, Magnani, Marina, Racano, Costantina, Bolzoni, Marina, Dalla Palma, Benedetta, Spolzino, Angelica, Manferdini, Cristina, Abati, Caterina, Toscani, Denise, Facchini, Andrea, Aversa, Franco
Publicado 2013

PD-L1/PD-1 Pattern of Expression Within the Bone Marrow Immune Microenvironment in Smoldering Myeloma and Active Multiple Myeloma Patients

por Costa, Federica, Vescovini, Rosanna, Marchica, Valentina, Storti, Paola, Notarfranchi, Laura, Dalla Palma, Benedetta, Toscani, Denise, Burroughs-Garcia, Jessica, Catarozzo, Maria Teresa, Sammarelli, Gabriella, Giuliani, Nicola
Publicado 2021

Bovine pestivirus is a new alternative virus for multiple myeloma oncolytic virotherapy

por Marchica, Valentina, Franceschi, Valentina, Vescovini, Rosanna, Storti, Paola, Vicario, Emanuela, Toscani, Denise, Zorzoli, Alessia, Airoldi, Irma, Dalla Palma, Benedetta, Campanini, Nicoletta, Martella, Eugenia, Mancini, Cristina, Costa, Federica, Donofrio, Gaetano, Giuliani, Nicola
Publicado 2020

[(18)F](2S,4R)-4-Fluoroglutamine as a New Positron Emission Tomography Tracer in Myeloma

por Valtorta, Silvia, Toscani, Denise, Chiu, Martina, Sartori, Andrea, Coliva, Angela, Brevi, Arianna, Taurino, Giuseppe, Grioni, Matteo, Ruffini, Livia, Vacondio, Federica, Zanardi, Franca, Bellone, Matteo, Moresco, Rosa Maria, Bussolati, Ovidio, Giuliani, Nicola
Publicado 2021

P830: IDENTIFICATION OF NOVEL TARGET GENES CORRELATED WITH 1Q21 AMPLIFICATION IN PATIENTS WITH SMOLDERING MYELOMA AND MULTIPLE MYELOMA

por Thomas Iannozzi, Nicolas, Burroughs Garcia, Jessica, Storti, Paola, Toscani, Denise, Marchica, Valentina, Franceschi, Valentina, Agnelli, Luca, Raimondi, Vincenzo, Todaro, Giannalisa, Lungu, Oxana, Bernardi, Matia, Sammarelli, Gabriella, Donofrio, Gaetano, Dalla Palma, Benedetta, Giuliani, Nicola
Publicado 2023

NAD(+)-Metabolizing Ectoenzymes in Remodeling Tumor–Host Interactions: The Human Myeloma Model

por Horenstein, Alberto L., Chillemi, Antonella, Quarona, Valeria, Zito, Andrea, Roato, Ilaria, Morandi, Fabio, Marimpietri, Danilo, Bolzoni, Marina, Toscani, Denise, Oldham, Robert J., Cuccioloni, Massimiliano, Sasser, A. Kate, Pistoia, Vito, Giuliani, Nicola, Malavasi, Fabio
Publicado 2015

Lenalidomide increases human dendritic cell maturation in multiple myeloma patients targeting monocyte differentiation and modulating mesenchymal stromal cell inhibitory properties

por Costa, Federica, Vescovini, Rosanna, Bolzoni, Marina, Marchica, Valentina, Storti, Paola, Toscani, Denise, Accardi, Fabrizio, Notarfranchi, Laura, Dalla Palma, Benedetta, Manferdini, Cristina, Manni, Sabrina, Todaro, Giannalisa, Lisignoli, Gina, Piazza, Francesco, Aversa, Franco, Giuliani, Nicola
Publicado 2017

Bone Marrow CX3CL1/Fractalkine is a New Player of the Pro-Angiogenic Microenvironment in Multiple Myeloma Patients

por Marchica, Valentina, Toscani, Denise, Corcione, Anna, Bolzoni, Marina, Storti, Paola, Vescovini, Rosanna, Ferretti, Elisa, Dalla Palma, Benedetta, Vicario, Emanuela, Accardi, Fabrizio, Mancini, Cristina, Martella, Eugenia, Ribatti, Domenico, Vacca, Angelo, Pistoia, Vito, Giuliani, Nicola
Publicado 2019

Immune response to SARS-CoV-2 mRNA vaccination and booster dose in patients with multiple myeloma and monoclonal gammopathies: impact of Omicron variant on the humoral response

por Storti, Paola, Marchica, Valentina, Vescovini, Rosanna, Franceschi, Valentina, Russo, Luca, Notarfranchi, Laura, Raimondi, Vincenzo, Toscani, Denise, Burroughs Garcia, Jessica, Costa, Federica, Dalla Palma, Benedetta, Iannozzi, Nicolas Thomas, Sammarelli, Gabriella, Donofrio, Gaetano, Giuliani, Nicola
Publicado 2022

Expression of CD38 in myeloma bone niche: A rational basis for the use of anti-CD38 immunotherapy to inhibit osteoclast formation

por Costa, Federica, Toscani, Denise, Chillemi, Antonella, Quarona, Valeria, Bolzoni, Marina, Marchica, Valentina, Vescovini, Rosanna, Mancini, Cristina, Martella, Eugenia, Campanini, Nicoletta, Schifano, Chiara, Bonomini, Sabrina, Accardi, Fabrizio, Horenstein, Alberto L., Aversa, Franco, Malavasi, Fabio, Giuliani, Nicola
Publicado 2017

Growth factor independence 1 expression in myeloma cells enhances their growth, survival, and osteoclastogenesis

por Petrusca, Daniela N, Toscani, Denise, Wang, Feng-Ming, Park, Cheolkyu, Crean, Colin D, Anderson, Judith L, Marino, Silvia, Mohammad, Khalid S, Zhou, Dan, Silbermann, Rebecca, Sun, Quanhong, Kurihara, Noriyoshi, Galson, Deborah L, Giuliani, Nicola, Roodman, G David
Publicado 2018