Low level DUX4 expression disrupts myogenesis through deregulation of myogenic gene expression

por Bosnakovski, Darko, Gearhart, Micah D., Toso, Erik A., Ener, Elizabeth T., Choi, Si Ho, Kyba, Michael
Publicado 2018

Antiapoptotic Protein FAIM2 is targeted by miR-3202, and DUX4 via TRIM21, leading to cell death and defective myogenesis

por Soliman, Hossam A. N., Toso, Erik A., Darwish, Inas E., Ali, Samia M., Kyba, Michael
Publicado 2022

High-throughput screening identifies inhibitors of DUX4-induced myoblast toxicity

por Bosnakovski, Darko, Choi, Si Ho, Strasser, Jessica M, Toso, Erik A, Walters, Michael A, Kyba, Michael
Publicado 2014

DNA-binding sequence specificity of DUX4

por Zhang, Yu, Lee, John K., Toso, Erik A., Lee, Joslynn S., Choi, Si Ho, Slattery, Matthew, Aihara, Hideki, Kyba, Michael
Publicado 2016

p53-independent DUX4 pathology in cell and animal models of facioscapulohumeral muscular dystrophy

por Bosnakovski, Darko, Gearhart, Micah D., Toso, Erik A., Recht, Olivia O., Cucak, Anja, Jain, Abhinav K., Barton, Michelle C., Kyba, Michael
Publicado 2017

A novel P300 inhibitor reverses DUX4-mediated global histone H3 hyperacetylation, target gene expression, and cell death

por Bosnakovski, Darko, da Silva, Meiricris T., Sunny, Sithara T., Ener, Elizabeth T., Toso, Erik A., Yuan, Ce, Cui, Ziyou, Walters, Michael A., Jadhav, Ajit, Kyba, Michael
Publicado 2019

Antagonism among DUX family members evolved from an ancestral toxic single homeodomain protein

por Bosnakovski, Darko, Toso, Erik A., Ener, Elizabeth T., Gearhart, Micah D., Yin, Lulu, Lüttmann, Felipe F., Magli, Alessandro, Shi, Ke, Kim, Johnny, Aihara, Hideki, Kyba, Michael
Publicado 2023

Enhanced differentiation of human induced pluripotent stem cells toward the midbrain dopaminergic neuron lineage through GLYPICAN‐4 downregulation

por Corti, Serena, Bonjean, Remi, Legier, Thomas, Rattier, Diane, Melon, Christophe, Salin, Pascal, Toso, Erik A., Kyba, Michael, Kerkerian‐Le Goff, Lydia, Maina, Flavio, Dono, Rosanna
Publicado 2021

Antagonism among DUX family members evolved from an ancestral toxic single homeodomain protein

por Bosnakovski, Darko, Toso, Erik A., Ener, Elizabeth T., Gearhart, Micah D., Yin, Lulu, Lüttmann, Felipe F., Magli, Alessandro, Shi, Ke, Kim, Johnny, Aihara, Hideki, Kyba, Michael
Publicado 2023

Inactivation of the CIC-DUX4 oncogene through P300/CBP inhibition, a therapeutic approach for CIC-DUX4 sarcoma

por Bosnakovski, Darko, Ener, Elizabeth T., Cooper, Mark S., Gearhart, Micah D., Knights, Kevin A., Xu, Natalie C., Palumbo, Christian A., Toso, Erik A., Marsh, Graham P., Maple, Hannah J., Kyba, Michael
Publicado 2021

Pax3-induced expansion enables the genetic correction of dystrophic satellite cells

por Filareto, Antonio, Rinaldi, Fabrizio, Arpke, Robert W., Darabi, Radbod, Belanto, Joseph J., Toso, Erik A., Miller, Auston Z., Ervasti, James M., McIvor, R. Scott, Kyba, Michael, Perlingeiro, Rita CR
Publicado 2015