Structure of human apurinic/apyrimidinic endonuclease 1 with the essential Mg(2+) cofactor

por Manvilla, Brittney A., Pozharski, Edwin, Toth, Eric A., Drohat, Alexander C.
Publicado 2013

Structural and Biophysical Characterization of the HCV E1E2 Heterodimer for Vaccine Development

por Toth, Eric A., Chagas, Andrezza, Pierce, Brian G., Fuerst, Thomas R.
Publicado 2021

A direct interaction between NQO1 and a chemotherapeutic dimeric naphthoquinone

por Pidugu, Lakshmi Swarna Mukhi, Mbimba, J.C. Emmanuel, Ahmad, Muqeet, Pozharski, Edwin, Sausville, Edward A., Emadi, Ashkan, Toth, Eric A.
Publicado 2016

Structure of engineered hepatitis C virus E1E2 ectodomain in complex with neutralizing antibodies

por Metcalf, Matthew C., Janus, Benjamin M., Yin, Rui, Wang, Ruixue, Guest, Johnathan D., Pozharski, Edwin, Law, Mansun, Mariuzza, Roy A., Toth, Eric A., Pierce, Brian G., Fuerst, Thomas R., Ofek, Gilad
Publicado 2023

Transamidase site-targeted agents alter the conformation of the transglutaminase cancer stem cell survival protein to reduce GTP binding activity and cancer stem cell survival

por Kerr, Candace, Szmacinski, Henryk, Fisher, Matthew L., Nance, Bailey, Lakowicz, Joseph R., Akbar, Abdullah, Keillor, Jeffrey W., Wong, Tin Lok, Godoy-Ruiz, Raquel, Toth, Eric A., Weber, David J., Eckert, Richard L.
Publicado 2016

Covalent Small Molecule Inhibitors of Ca(2+)-Bound S100B

por Cavalier, Michael C., Pierce, Adam D., Wilder, Paul T., Alasady, Milad J., Hartman, Kira G., Neau, David B., Foley, Timothy L., Jadhav, Ajit, Maloney, David J., Simeonov, Anton, Toth, Eric A., Weber, David J.
Publicado 2014

Hydroxylated Dimeric Naphthoquinones Increase the Generation of Reactive Oxygen Species, Induce Apoptosis of Acute Myeloid Leukemia Cells and Are Not Substrates of the Multidrug Re...

por Lapidus, Rena G., Carter-Cooper, Brandon A., Sadowska, Mariola, Choi, Eun Yong, Wonodi, Omasiri, Muvarak, Nidal, Natarajan, Karthika, Pidugu, Lakshmi S., Jaiswal, Anil, Toth, Eric A., Rassool, Feyruz V., Etemadi, Arash, Sausville, Edward A., Baer, Maria R., Emadi, Ashkan
Publicado 2016

Skin Vaccination with Ebola Virus Glycoprotein Using a Polyphosphazene-Based Microneedle Patch Protects Mice against Lethal Challenge

por Romanyuk, Andrey, Wang, Ruixue, Marin, Alexander, Janus, Benjamin M., Felner, Eric I., Xia, Dengning, Goez-Gazi, Yenny, Alfson, Kendra J., Yunus, Abdul S., Toth, Eric A., Ofek, Gilad, Carrion, Ricardo, Prausnitz, Mark R., Fuerst, Thomas R., Andrianov, Alexander K.
Publicado 2022

Induction of broadly neutralizing antibodies using a secreted form of the hepatitis C virus E1E2 heterodimer as a vaccine candidate

por Wang, Ruixue, Suzuki, Saori, Guest, Johnathan D., Heller, Brigitte, Almeda, Maricar, Andrianov, Alexander K., Marin, Alexander, Mariuzza, Roy A., Keck, Zhen-Yong, Foung, Steven K. H., Yunus, Abdul S., Pierce, Brian G., Toth, Eric A., Ploss, Alexander, Fuerst, Thomas R.
Publicado 2022

Engineering subtilisin proteases that specifically degrade active RAS

por Chen, Yingwei, Toth, Eric A., Ruan, Biao, Choi, Eun Jung, Simmerman, Richard, Chen, Yihong, He, Yanan, Wang, Ruixue, Godoy-Ruiz, Raquel, King, Harlan, Custer, Gregory, Travis Gallagher, D., Rozak, David A., Solomon, Melani, Muro, Silvia, Weber, David J., Orban, John, Fuerst, Thomas R., Bryan, Philip N.
Publicado 2021