The Landscape of Non-Viral Gene Augmentation Strategies for Inherited Retinal Diseases

por Toualbi, Lyes, Toms, Maria, Moosajee, Mariya
Publicado 2021

USH2A-retinopathy: From genetics to therapeutics

por Toualbi, Lyes, Toms, Maria, Moosajee, Mariya
Publicado 2020

Gene Augmentation of CHM Using Non-Viral Episomal Vectors in Models of Choroideremia

por Toualbi, Lyes, Toms, Maria, Almeida, Patrick Vingadas, Harbottle, Richard, Moosajee, Mariya
Publicado 2023

Generation of two human control iPS cell lines (UCLi016-A and UCLi017-A) from healthy donors with no known ocular conditions

por Méjécase, Cécile, Harding, Philippa, Sarkar, Hajrah, Eintracht, Jonathan, Lima Cunha, Dulce, Toualbi, Lyes, Moosajee, Mariya
Publicado 2020

Generation of human iPSC line (UCLi013-A) from a patient with microphthalmia and aniridia, carrying a heterozygous missense mutation c.372C>A p.(Asn124Lys) in PAX6

por Harding, Philippa, Lima Cunha, Dulce, Méjécase, Cécile, Eintracht, Jonathan, Toualbi, Lyes, Sarkar, Hajrah, Moosajee, Mariya
Publicado 2021

Generation of two human iPSC lines from patients with autosomal dominant retinitis pigmentosa (UCLi014-A) and autosomal recessive Leber congenital amaurosis (UCLi015-A), associated...

por Sarkar, Hajrah, Méjécase, Cécile, Harding, Philippa, Eintracht, Jonathan, Toualbi, Lyes, Cunha, Dulce Lima, Moosajee, Mariya
Publicado 2021

Loss of the crumbs cell polarity complex disrupts epigenetic transcriptional control and cell cycle progression in the developing retina

por Owen, Nicholas, Toms, Maria, Tian, Yuan, Toualbi, Lyes, Richardson, Rose, Young, Rodrigo, Tracey‐White, Dhani, Dhami, Pawan, Beck, Stephan, Moosajee, Mariya
Publicado 2023

AAV-Mediated Gene Delivery to 3D Retinal Organoids Derived from Human Induced Pluripotent Stem Cells

por Garita-Hernandez, Marcela, Routet, Fiona, Guibbal, Laure, Khabou, Hanen, Toualbi, Lyes, Riancho, Luisa, Reichman, Sacha, Duebel, Jens, Sahel, Jose-Alain, Goureau, Olivier, Dalkara, Deniz
Publicado 2020

Control of Microbial Opsin Expression in Stem Cell Derived Cones for Improved Outcomes in Cell Therapy

por Garita-Hernandez, Marcela, Chaffiol, Antoine, Guibbal, Laure, Routet, Fiona, Khabou, Hanen, Riancho, Luisa, Toualbi, Lyes, Picaud, Serge, Sahel, José-Alain, Goureau, Olivier, Duebel, Jens, Dalkara, Deniz
Publicado 2021

Optogenetic Light Sensors in Human Retinal Organoids

por Garita-Hernandez, Marcela, Guibbal, Laure, Toualbi, Lyes, Routet, Fiona, Chaffiol, Antoine, Winckler, Celine, Harinquet, Marylin, Robert, Camille, Fouquet, Stephane, Bellow, Sebastien, Sahel, José-Alain, Goureau, Olivier, Duebel, Jens, Dalkara, Deniz
Publicado 2018