Congenital neutropenia: disease models guiding new treatment strategies

por Touw, Ivo P.
Publicado 2022

RUNX1 Mutations in the Leukemic Progression of Severe Congenital Neutropenia

por Olofsen, Patricia A., Touw, Ivo P.
Publicado 2020

Mutant allelic burden in acute myeloid leukaemia: Why bother?

por Touw, Ivo P., Sanders, Mathijs A.
Publicado 2019

Analysis of Jak2 Catalytic Function by Peptide Microarrays: The Role of the JH2 Domain and V617F Mutation

por Sanz, Arturo, Ungureanu, Daniela, Pekkala, Tuija, Ruijtenbeek, Rob, Touw, Ivo P., Hilhorst, Riet, Silvennoinen, Olli
Publicado 2011

Transcriptional Reprogramming of CD11b(+)Esam(hi) Dendritic Cell Identity and Function by Loss of Runx3

por Dicken, Joseph, Mildner, Alexander, Leshkowitz, Dena, Touw, Ivo P., Hantisteanu, Shay, Jung, Steffen, Groner, Yoram
Publicado 2013

Sustained Receptor Activation and Hyperproliferation in Response to Granulocyte Colony-stimulating Factor (G-CSF) in Mice with a Severe Congenital Neutropenia/Acute Myeloid Leukemi...

por Hermans, Mirjam H.A., Antonissen, Claudia, Ward, Alister C., Mayen, Angelique E.M., Ploemacher, Rob E., Touw, Ivo P.
Publicado 1999

The Antioxidant Protein Peroxiredoxin 4 Is Epigenetically Down Regulated in Acute Promyelocytic Leukemia

por Palande, Karishma K., Beekman, Renee, van der Meeren, Lotte E., Beverloo, H. Berna, Valk, Peter J. M., Touw, Ivo P.
Publicado 2011

HAT: Hypergeometric Analysis of Tiling-arrays with application to promoter-GeneChip data

por Taskesen, Erdogan, Beekman, Renee, de Ridder, Jeroen, Wouters, Bas J, Peeters, Justine K, Touw, Ivo P, Reinders, Marcel JT, Delwel, Ruud
Publicado 2010

Loss of Ercc1 Results in a Time- and Dose-Dependent Reduction of Proliferating Early Hematopoietic Progenitors

por Verhagen-Oldenampsen, Judith H. E., Haanstra, Jurgen R., van Strien, Paulina M. H., Valkhof, Marijke, Touw, Ivo P., von Lindern, Marieke
Publicado 2012

Retroviral Integration Mutagenesis in Mice and Comparative Analysis in Human AML Identify Reduced PTP4A3 Expression as a Prognostic Indicator

por Beekman, Renée, Valkhof, Marijke, Erkeland, Stefan J., Taskesen, Erdogan, Rockova, Veronika, Peeters, Justine K., Valk, Peter J. M., Löwenberg, Bob, Touw, Ivo P.
Publicado 2011

Novel Point Mutation in the Extracellular Domain of the Granulocyte Colony-Stimulating Factor (G-Csf) Receptor in a Case of Severe Congenital Neutropenia Hyporesponsive to G-Csf Tr...

por Ward, Alister C., van Aesch, Yvette M., Gits, Judith, Schelen, Anita M., de Koning, John P., van Leeuwen, Daphne, Freedman, Melvin H., Touw, Ivo P.
Publicado 1999

S160: GATA2B HAPLOINSUFFICIENCY CAUSES ABERRANT TRANSCRIPTIONAL REGULATORY SIGNATURES IN HSPCS RESULTING IN MYELOID AND ERYTHROID DYSPLASIA IN ZEBRAFISH

por Zhang, Wei, Gioacchino, Emanuele, Koyunlar, Cansu, Zink, Joke, de Looper, Hans, Gussinklo, Kirsten J., Hoogenboezem, Remco, Bosch, Dennis, Bindels, Eric, Touw, Ivo P., de Pater, Emma
Publicado 2023

Gata2-regulated Gfi1b expression controls endothelial programming during endothelial-to-hematopoietic transition

por Koyunlar, Cansu, Gioacchino, Emanuele, Vadgama, Disha, de Looper, Hans, Zink, Joke, ter Borg, Mariette N. D., Hoogenboezem, Remco, Havermans, Marije, Sanders, Mathijs A., Bindels, Eric, Dzierzak, Elaine, Touw, Ivo P., de Pater, Emma
Publicado 2023

Myeloid cells promote interferon signaling-associated deterioration of the hematopoietic system

por Feyen, Jacqueline, Ping, Zhen, Chen, Lanpeng, van Dijk, Claire, van Tienhoven, Tim V. D., van Strien, Paulina M. H., Hoogenboezem, Remco M., Wevers, Michiel J. W., Sanders, Mathijs A., Touw, Ivo P., Raaijmakers, Marc H. G. P.
Publicado 2022

Truncated CSF3 receptors induce pro‐inflammatory responses in severe congenital neutropenia

por Olofsen, Patricia A., Bosch, Dennis A., de Looper, Hans W. J., van Strien, Paulina M. H., Hoogenboezem, Remco M., Roovers, Onno, van der Velden, Vincent H. J., Bindels, Eric M. J., De Pater, Emma M., Touw, Ivo P.
Publicado 2022

The European Guidelines on Diagnosis and Management of Neutropenia in Adults and Children: A Consensus Between the European Hematology Association and the EuNet-INNOCHRON COST Acti...

por Fioredda, Francesca, Skokowa, Julia, Tamary, Hannah, Spanoudakis, Michail, Farruggia, Piero, Almeida, Antonio, Guardo, Daniela, Höglund, Petter, Newburger, Peter E., Palmblad, Jan, Touw, Ivo P., Zeidler, Cornelia, Warren, Alan J., Dale, David C., Welte, Karl, Dufour, Carlo, Papadaki, Helen A.
Publicado 2023

Malignant Transformation Involving CXXC4 Mutations Identified in a Leukemic Progression Model of Severe Congenital Neutropenia

por Olofsen, Patricia A., Fatrai, Szabolcs, van Strien, Paulina M.H., Obenauer, Julia C., de Looper, Hans W.J., Hoogenboezem, Remco M., Erpelinck-Verschueren, Claudia A.J., Vermeulen, Michael P.W.M., Roovers, Onno, Haferlach, Torsten, Jansen, Joop H., Ghazvini, Mehrnaz, Bindels, Eric M.J., Schneider, Rebekka K., de Pater, Emma M., Touw, Ivo P.
Publicado 2020