Blockade of IL-36 Receptor Signaling Does Not Prevent from TNF-Induced Arthritis

por Derer, Anja, Groetsch, Bettina, Harre, Ulrike, Böhm, Christina, Towne, Jennifer, Schett, Georg, Frey, Silke, Hueber, Axel J.
Publicado 2014

The severity of experimental arthritis is independent of IL-36 receptor signaling

por Lamacchia, Céline, Palmer, Gaby, Rodriguez, Emiliana, Martin, Praxedis, Vigne, Solenne, Seemayer, Christian A, Talabot-Ayer, Dominique, Towne, Jennifer E, Gabay, Cem
Publicado 2013

The PAR2 signal peptide prevents premature receptor cleavage and activation

por Liu, Belinda, Lee, Grace, Wu, Jiejun, Deming, Janise, Kuei, Chester, Harrington, Anthony, Wang, Lien, Towne, Jennifer, Lovenberg, Timothy, Liu, Changlu, Sun, Siquan
Publicado 2020

Opposing activities of two novel members of the IL-1 ligand family regulate skin inflammation

por Blumberg, Hal, Dinh, Huyen, Trueblood, Esther S., Pretorius, James, Kugler, David, Weng, Ning, Kanaly, Suzanne T., Towne, Jennifer E., Willis, Cynthia R., Kuechle, Melanie K., Sims, John E., Peschon, Jacques J.
Publicado 2007

The CSF-1-receptor inhibitor, JNJ-40346527 (PRV-6527), reduced inflammatory macrophage recruitment to the intestinal mucosa and suppressed murine T cell mediated colitis

por Manthey, Carl L., Moore, Beverley A., Chen, Yanqing, Loza, Matthew J., Yao, Xiang, Liu, Hao, Belkowski, Stanley M., Raymond-Parks, Holly, Dunford, Paul J., Leon, Francisco, Towne, Jennifer E., Plevy, Scott E.
Publicado 2019

Differing roles for short chain fatty acids and GPR43 agonism in the regulation of intestinal barrier function and immune responses

por D’Souza, Warren N., Douangpanya, Jason, Mu, Sharon, Jaeckel, Peter, Zhang, Ming, Maxwell, Joseph R., Rottman, James B., Labitzke, Katja, Willee, Angela, Beckmann, Holger, Wang, Yingcai, Li, Yang, Schwandner, Ralf, Johnston, James A., Towne, Jennifer E., Hsu, Hailing
Publicado 2017

Low-Dose Interleukin-2 Ameliorates Colitis in a Preclinical Humanized Mouse Model

por Goettel, Jeremy A., Kotlarz, Daniel, Emani, Rohini, Canavan, James B., Konnikova, Liza, Illig, David, Frei, Sandra M., Field, Michael, Kowalik, Matthew, Peng, Kaiyue, Gringauz, Jordan, Mitsialis, Vanessa, Wall, Sarah M., Tsou, Amy, Griffith, Alexandra E., Huang, Ying, Friedman, Joshua R., Towne, Jennifer E., Plevy, Scott E., O’Hara Hall, Aisling, Snapper, Scott B.
Publicado 2019

Identification of small-molecule protein–protein interaction inhibitors for NKG2D

por Thompson, Aaron A., Harbut, Michael B., Kung, Pei-Pei, Karpowich, Nathan K., Branson, Jeffrey D., Grant, Joanna C., Hagan, Deborah, Pascual, Heather A., Bai, Guoyun, Zavareh, Reza Beheshti, Coate, Heather R., Collins, Bernard C., Côte, Marjorie, Gelin, Christine F., Damm-Ganamet, Kelly L., Gholami, Hadi, Huff, Adam R., Limon, Luis, Lumb, Kevin J., Mak, Puiying A., Nakafuku, Kohki M., Price, Edmund V., Shih, Amy Y., Tootoonchi, Mandana, Vellore, Nadeem A., Wang, Jocelyn, Wei, Na, Ziff, Jeannie, Berger, Scott B., Edwards, James P., Gardet, Agnès, Sun, Siquan, Towne, Jennifer E., Venable, Jennifer D., Shi, Zhicai, Venkatesan, Hariharan, Rives, Marie-Laure, Sharma, Sujata, Shireman, Brock T., Allen, Samantha J.
Publicado 2023